Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy X Li, Y Song Journal of Hematology & Oncology 13, 1-14, 2020 | 270 | 2020 |
Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine JJ Qin, X Li, C Hunt, W Wang, H Wang, R Zhang Genes & diseases 5 (3), 204-219, 2018 | 91 | 2018 |
Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ X Li, J Sheng, G Huang, R Ma, F Yin, D Song, C Zhao, S Ma European journal of medicinal chemistry 97, 32-41, 2015 | 71 | 2015 |
Targeting MDM2 for novel molecular therapy: Beyond oncology W Wang, JJ Qin, M Rajaei, X Li, X Yu, C Hunt, R Zhang Medicinal Research Reviews 40 (3), 856-880, 2020 | 67 | 2020 |
Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ X Li, S Ma European journal of medicinal chemistry 95, 1-15, 2015 | 61 | 2015 |
Structure, function and inhibition of critical protein–protein interactions involving mixed lineage leukemia 1 and its fusion oncoproteins X Li, Y Song Journal of Hematology & Oncology 14 (1), 1-33, 2021 | 44 | 2021 |
MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53 W Wang, JW Cheng, JJ Qin, B Hu, X Li, B Nijampatnam, SE Velu, J Fan, ... Cancer letters 459, 156-167, 2019 | 40 | 2019 |
A Novel Inhibitor of MDM2 Oncogene Blocks Metastasis of Hepatocellular Carcinoma and Overcomes Chemoresistance RZ Wei Wang, Bo Hu, Jiang-Jiang Qin, Jianwen Cheng, Xin Li, Mehrdad Rajaeia ... Genes & Diseases, 2019 | 37 | 2019 |
Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives C Cong, H Wang, Y Hu, C Liu, S Ma, X Li, J Cao, S Ma European journal of medicinal chemistry 46 (7), 3105-3111, 2011 | 34 | 2011 |
Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review X Li, Y Song European Journal of Medicinal Chemistry, 115772, 2023 | 32 | 2023 |
Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen JJ Qin, X Li, W Wang, X Zi, R Zhang Frontiers in Pharmacology 8, 917, 2017 | 28 | 2017 |
Inhibiting β-catenin by β-carboline-type MDM2 inhibitor for pancreatic cancer therapy JJ Qin, W Wang, X Li, R Zhang Frontiers in pharmacology 9, 320167, 2018 | 25 | 2018 |
Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease S Nie, J Zhao, X Wu, Y Yao, F Wu, YL Lin, X Li, AR Kneubehl, MB Vogt, ... European journal of medicinal chemistry 225, 113767, 2021 | 24 | 2021 |
Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms W Wang, JJ Qin, X Li, G Tao, Q Wang, X Wu, J Zhou, X Zi, R Zhang Carcinogenesis 39 (8), 1026-1036, 2018 | 24 | 2018 |
Synthesis and antibacterial evaluation of novel 11, 4 ″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria X Li, S Ma, M Yan, Y Wang, S Ma European journal of medicinal chemistry 59, 209-217, 2013 | 22 | 2013 |
Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth F Wu, S Nie, Y Yao, T Huo, X Li, X Wu, J Zhao, YL Lin, Y Zhang, Q Mo, ... Theranostics 11 (17), 8172, 2021 | 18 | 2021 |
A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth X Li, Y Yao, F Wu, Y Song Journal of Hematology & Oncology 15 (1), 41, 2022 | 15 | 2022 |
Synthesis and Biological Evaluation of Novel FtsZ‐targeted 3‐arylalkoxy‐2, 6‐difluorobenzamides as Potential Antimicrobial Agents S Qiang, C Wang, H Venter, X Li, Y Wang, L Guo, R Ma, S Ma Chemical biology & drug design 87 (2), 257-264, 2016 | 13 | 2016 |
Synthesis and antibacterial activity of 4″-O-(trans-β-arylacrylamido)carbamoyl azithromycin analogs M Yan, X Ma, R Dong, X Li, C Zhao, Z Guo, Y Shen, F Liu, R Ma, S Ma European Journal of Medicinal Chemistry 103, 506-515, 2015 | 13 | 2015 |
Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division WC Chai, JJ Whittall, SW Polyak, K Foo, X Li, CJ Dutschke, AD Ogunniyi, ... Frontiers in Microbiology, 3266, 2022 | 11 | 2022 |