Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity S Navina, C Acharya, JP DeLany, LS Orlichenko, CJ Baty, SS Shiva, ... Science translational medicine 3 (107), 107ra110-107ra110, 2011 | 481 | 2011 |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... Nature genetics 44 (12), 1349-1354, 2012 | 417 | 2012 |
Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development LS Orlichenko, DC Radisky Clinical & experimental metastasis 25, 593-600, 2008 | 324 | 2008 |
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer BA Boone, L Orlichenko, NE Schapiro, P Loughran, GC Gianfrate, JT Ellis, ... Cancer gene therapy 22 (6), 326-334, 2015 | 174 | 2015 |
Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells L Orlichenko, B Huang, E Krueger, MA McNiven Journal of Biological Chemistry 281 (8), 4570-4579, 2006 | 137 | 2006 |
Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation L Orlichenko, SG Weller, H Cao, EW Krueger, M Awoniyi, ... Molecular biology of the cell 20 (19), 4140-4152, 2009 | 71 | 2009 |
Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini LS Orlichenko, J Behari, TH Yeh, S Liu, DB Stolz, AK Saluja, VP Singh American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010 | 56 | 2010 |
The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin L Orlichenko, R Geyer, M Yanagisawa, D Khauv, ES Radisky, ... Journal of Biological Chemistry 285 (25), 19153-19161, 2010 | 51 | 2010 |
An extensive targeted proteomic analysis of disease-related protein biomarkers in urine from healthy donors BM Nolen, LS Orlichenko, A Marrangoni, L Velikokhatnaya, D Prosser, ... PloS one 8 (5), e63368, 2013 | 30 | 2013 |
Alzheimer’s Disease Genetics Consortium DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... LaRusch, J, 1349-1354, 2012 | 21 | 2012 |
ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis L Orlichenko, DB Stolz, P Noel, J Behari, S Liu, VP Singh Journal of Biological Chemistry 287 (29), 24284-24293, 2012 | 18 | 2012 |
Src dependent pancreatic acinar injury can be initiated independent of an increase in cytosolic calcium V Mishra, R Cline, P Noel, J Karlsson, CJ Baty, L Orlichenko, K Patel, ... PloS one 8 (6), e66471, 2013 | 9 | 2013 |
The caveolae internalization machinery LS Orlichenko, MA McNiven Advances in Molecular and Cell Biology 36, 57-77, 2005 | 3 | 2005 |
The second most common PRSS1 haplotype lowers trypsin expression and reduces pancreatitis risk J LaRusch, L Orlichenko, V Singh, DC Whitcomb Pancreas 40 (8), 1333-1334, 2011 | 1 | 2011 |
Trafficking of Cathepsin B Containing Organelles to the Autophagosome in an ARF-1 Dependent Manner is Required for Caerulein Induced Trypsinogen Activation L Orlichenko, V Singh Gastroenterology 5 (140), S-53, 2011 | 1 | 2011 |
High-Throughput Next Generation RNA Sequencing of Pancreatic Cancer Transcriptome Identifies Novel NcRNA Biomarkers That Uniquely Associates With the Disease L Orlichenko, R Brand, AE Lokshin PANCREAS 42 (8), 1374-1374, 2013 | | 2013 |
WS8. 9 Identification of high frequency non-CFTR genetic risk factors J LaRusch, L Orlichenko, V Singh, DC Whitcomb Journal of Cystic Fibrosis 11, S18, 2012 | | 2012 |
82 Lipotoxicity Results in Lethality From Caerulein Induced Acute Pancreatitis in Obese Mice C Durgampudi, C Acharya, R Cline, L Orlichenko, S Navina, V Singh Gastroenterology 5 (142), S-20, 2012 | | 2012 |
Vincristine Reduces L-Asparaginase Induced Acute Pancreatitis (AP) By Preventing Procathepsin B Trafficking and Trypsinogen Activation D Yadav, H Kim, LS Orlichenko, VP Singh PANCREAS 40 (8), 1363-1364, 2011 | | 2011 |
ARF-1 Regulates Trypsinogen Activation via Procathepsin B Trafficking and Autophagic Maturation During Caerulein Pancreatitis L Orlichenko, D Stolz, J Behari, S Liu, V Singh PANCREAS 40 (8), 1345-1346, 2011 | | 2011 |