Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease SB Petkova, S Akilesh, TJ Sproule, GJ Christianson, H Al Khabbaz, ... International immunology 18 (12), 1759-1769, 2006 | 656 | 2006 |
The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs DC Roopenian, GJ Christianson, TJ Sproule, AC Brown, S Akilesh, ... The Journal of Immunology 170 (7), 3528-3533, 2003 | 515 | 2003 |
Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress X Wang, SA Phelan, K Forsman-Semb, EF Taylor, C Petros, A Brown, ... Journal of Biological Chemistry 278 (27), 25179-25190, 2003 | 367 | 2003 |
Blocking FSH induces thermogenic adipose tissue and reduces body fat P Liu, Y Ji, T Yuen, E Rendina-Ruedy, VE DeMambro, S Dhawan, ... Nature 546 (7656), 107-112, 2017 | 303 | 2017 |
A synthetic niche for nephron progenitor cells AC Brown, SD Muthukrishnan, L Oxburgh Developmental cell 34 (2), 229-241, 2015 | 193 | 2015 |
The immunogenomics of minor histocompatibility antigens D Roopenian, EY Choi, A Brown Immunological reviews 190 (1), 86-94, 2002 | 189 | 2002 |
Role for compartmentalization in nephron progenitor differentiation AC Brown, SD Muthukrishnan, JA Guay, DC Adams, DA Schafer, ... Proceedings of the National Academy of Sciences 110 (12), 4640-4645, 2013 | 168 | 2013 |
FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney JL Fetting, JA Guay, MJ Karolak, RV Iozzo, DC Adams, DE Maridas, ... Development 141 (1), 17-27, 2014 | 160 | 2014 |
BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism U Blank, A Brown, DC Adams, MJ Karolak, L Oxburgh Development 136 (21), 3557-3566, 2009 | 142 | 2009 |
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development AC Brown, D Adams, M de Caestecker, X Yang, R Friesel, L Oxburgh Development 138 (23), 5099-5112, 2011 | 109 | 2011 |
A renewable source of human beige adipocytes for development of therapies to treat metabolic syndrome S Su, AR Guntur, DC Nguyen, SS Fakory, CC Doucette, C Leech, ... Cell reports 25 (11), 3215-3228. e9, 2018 | 58 | 2018 |
Searching QTL by gene expression: analysis of diabesity AC Brown, WI Olver, CJ Donnelly, ME May, JK Naggert, DJ Shaffer, ... BMC genetics 6, 1-9, 2005 | 52 | 2005 |
Quantitative gene expression profiling implicates genes for susceptibility and resistance to alveolar bone loss GT Hart, DJ Shaffer, S Akilesh, AC Brown, L Moran, DC Roopenian, ... Infection and immunity 72 (8), 4471-4479, 2004 | 51 | 2004 |
Disparate levels of beta-catenin activity determine nephron progenitor cell fate H Ramalingam, AR Fessler, A Das, MT Valerius, J Basta, L Robbins, ... Developmental biology 440 (1), 13-21, 2018 | 42 | 2018 |
A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells Q Guo, A Kim, B Li, A Ransick, H Bugacov, X Chen, N Lindström, A Brown, ... Elife 10, e64444, 2021 | 37 | 2021 |
BMP signaling in the nephron progenitor niche L Oxburgh, AC Brown, J Fetting, B Hill Pediatric Nephrology 26, 1491-1497, 2011 | 35 | 2011 |
p53 Enables metabolic fitness and self-renewal of nephron progenitor cells Y Li, J Liu, W Li, A Brown, M Baddoo, M Li, T Carroll, L Oxburgh, Y Feng, ... Development 142 (7), 1228-1241, 2015 | 33 | 2015 |
Through regulation of TCR expression levels, an Idd7 region gene (s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in … DV Serreze, CM Choisy-Rossi, AE Grier, TM Holl, HD Chapman, ... The Journal of Immunology 180 (5), 3250-3259, 2008 | 30 | 2008 |
ExQuest, a novel method for displaying quantitative gene expression from ESTs AC Brown, K Kai, ME May, DC Brown, DC Roopenian Genomics 83 (3), 528-539, 2004 | 24 | 2004 |
Bone morphogenetic protein signaling in nephron progenitor cells L Oxburgh, AC Brown, SD Muthukrishnan, JL Fetting Pediatric Nephrology 29, 531-536, 2014 | 23 | 2014 |