Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host M Meisel, R Hinterleitner, A Pacis, L Chen, ZM Earley, T Mayassi, ... Nature 557 (7706), 580-584, 2018 | 391 | 2018 |
DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions M Buscarlet, S Provost, YF Zada, A Barhdadi, V Bourgoin, G Lépine, ... Blood, The Journal of the American Society of Hematology 130 (6), 753-762, 2017 | 390 | 2017 |
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy F Binet, G Cagnone, S Crespo-Garcia, M Hata, M Neault, A Dejda, ... Science 369 (6506), eaay5356, 2020 | 204 | 2020 |
The ‘Marx’of Groucho on development and disease M Buscarlet, S Stifani Trends in cell biology 17 (7), 353-361, 2007 | 175 | 2007 |
Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A M Buscarlet, S Provost, YF Zada, V Bourgoin, L Mollica, MP Dubé, ... Blood, The Journal of the American Society of Hematology 132 (3), 277-280, 2018 | 141 | 2018 |
The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function V Krasteva, M Buscarlet, A Diaz-Tellez, MA Bernard, GR Crabtree, ... Blood, The Journal of the American Society of Hematology 120 (24), 4720-4732, 2012 | 133 | 2012 |
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance M Buscarlet, V Krasteva, L Ho, C Simon, J Hébert, B Wilhelm, ... Blood, The Journal of the American Society of Hematology 123 (11), 1720-1728, 2014 | 125 | 2014 |
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition S Crespo-Garcia, PR Tsuruda, A Dejda, RD Ryan, F Fournier, SY Chaney, ... Cell metabolism 33 (4), 818-832. e7, 2021 | 121 | 2021 |
Concise review: age-related clonal hematopoiesis: stem cells tempting the devil L Busque, M Buscarlet, L Mollica, RL Levine Stem Cells 36 (9), 1287-1294, 2018 | 91 | 2018 |
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy K Miloudi, M Oubaha, C Ménard, A Dejda, V Guber, G Cagnone, ... Proceedings of the National Academy of Sciences 116 (10), 4538-4547, 2019 | 88 | 2019 |
High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential L Busque, M Sun, M Buscarlet, S Ayachi, YF Zada, S Provost, V Bourgoin, ... Blood Advances 4 (11), 2430-2438, 2020 | 69 | 2020 |
Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1, repressor peptides M Buscarlet, A Perin, A Laing, JM Brickman, S Stifani Journal of Biological Chemistry 283 (36), 24881-24888, 2008 | 46 | 2008 |
Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2 M Buscarlet, A Tessier, S Provost, L Mollica, L Busque Experimental hematology 44 (11), 1072-1084, 2016 | 41 | 2016 |
60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations S Ayachi, M Buscarlet, L Busque Experimental Hematology 83, 2-11, 2020 | 36 | 2020 |
Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE: Hes1-mediated inhibition of neuronal differentiation R Ciarapica, L Methot, Y Tang, R Lo, R Dali, M Buscarlet, F Locatelli, ... Cell Death & Differentiation 21 (2), 321-332, 2014 | 30 | 2014 |
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions TH Shin, Y Zhou, S Chen, S Cordes, MZ Grice, X Fan, BC Lee, ... Blood, The Journal of the American Society of Hematology 140 (16), 1774-1789, 2022 | 26 | 2022 |
Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1 M Buscarlet, R Hermann, R Lo, Y Tang, K Joachim, S Stifani PloS one 4 (12), e8107, 2009 | 26 | 2009 |
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results S Crespo-Garcia, F Fournier, R Diaz-Marin, S Klier, D Ragusa, L Masaki, ... Nature Medicine 30 (2), 443-454, 2024 | 25 | 2024 |
Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation EMMA Andriessen, F Binet, F Fournier, M Hata, A Dejda, G Mawambo, ... EMBO molecular medicine 13 (5), e11754, 2021 | 15 | 2021 |
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life M Hata, M Hata, EMMA Andriessen, R Juneau, F Pilon, S Crespo-Garcia, ... The Journal of Clinical Investigation 133 (4), 2023 | 13 | 2023 |