Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension RB Kasetti, P Maddineni, PD Patel, C Searby, VC Sheffield, GS Zode Journal of Biological Chemistry 293 (25), 9854-9868, 2018 | 79 | 2018 |
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma P Maddineni, RB Kasetti, PD Patel, JC Millar, C Kiehlbauch, AF Clark, ... Molecular neurodegeneration 15 (1), 1-20, 2020 | 57 | 2020 |
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load RB Kasetti, PD Patel, P Maddineni, S Patil, C Kiehlbauch, JC Millar, ... Nature communications 11 (1), 1-14, 2020 | 50 | 2020 |
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma PD Patel, YL Chen, RB Kasetti, P Maddineni, W Mayhew, JC Millar, ... Proceedings of the National Academy of Sciences 118 (16), e2022461118, 2021 | 37 | 2021 |
Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa AA Rowe, PD Patel, R Gordillo, KJ Wert JCI insight 6 (17), 2021 | 19 | 2021 |
Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork RB Kasetti, PD Patel, P Maddineni, GS Zode PloS one 15 (6), e0232111, 2020 | 16 | 2020 |
Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments PD Patel, RB Kasetti, SK Sonkusare, GS Zode Molecular vision 26, 434, 2020 | 2 | 2020 |
Inhibition of chronic endoplasmic reticulum stress rescues myocilin-associated glaucoma via stimulation of autophagic flux in the TM R Kasetti, P Patel, G Zode Investigative Ophthalmology & Visual Science 59 (9), 6035-6035, 2018 | 1 | 2018 |
Correction: Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork RB Kasetti, PD Patel, P Maddineni, GS Zode Plos one 15 (8), e0238408, 2020 | | 2020 |
Impaired TRPV4-eNOS signaling in glaucomatous trabecular meshwork contributes to elevation of intraocular pressure P Patel, R Kasetti, P Maddineni, JC Millar, YL Chen, SK Sonkusare, ... Investigative Ophthalmology & Visual Science 61 (7), 2784-2784, 2020 | | 2020 |
Increased expression of the chronic ER stress-induced transcriptional factor, ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load R Kasetti, P Patel, P Maddineni, S Patil, C Kiehlbauch, JC Millar, ... Investigative Ophthalmology & Visual Science 61 (7), 1236-1236, 2020 | | 2020 |
The Role of Mechanosensory TRPV4 Channels and Nitric Oxide Signaling in Intraocular Pressure Homeostasis, and Its Impairment in Glaucoma P Patel University of North Texas Health Science Center at Fort Worth, 2020 | | 2020 |
Glucocorticoid-induced glaucomatous neurodegeneration is associated with demyelination of optic nerve axons and infiltration of immune cells. R Kasetti, PD Patel, G Zode Investigative Ophthalmology & Visual Science 60 (9), 683-683, 2019 | | 2019 |
Ex-vivo cultured human anterior segment model to study the effects of glaucoma factors on trabecular meshwork R Kasetti, PD Patel, G Zode Investigative Ophthalmology & Visual Science 60 (9), 5160-5160, 2019 | | 2019 |
Activation of TRPV4 channels reduces IOP and improves outflow facility by regulating eNOS dependent NO release from the TM PD Patel, R Kasetti, JC Millar, G Zode Investigative Ophthalmology & Visual Science 60 (9), 6473-6473, 2019 | | 2019 |
Increased expression of ATF4 in trabecular meshwork elevates IOP and leads to glaucomatous neurodegeneration by increasing secretory protein load of the endoplasmic reticulum G Zode, R Kasetti, PD Patel, V Sheffield Investigative Ophthalmology & Visual Science 60 (9), 5215-5215, 2019 | | 2019 |
TRPV4-mediated regulation of intraocular pressure and outflow facility in mouse model of glucocorticoid-induced ocular hypertension P Patel, JC Millar, R Kasetti, G Zode Investigative Ophthalmology & Visual Science 59 (9), 4728-4728, 2018 | | 2018 |
Glucocorticoid-induced ocular hypertension leads to progressive retinal ganglion cell loss, impaired axonal transport and optic nerve degeneration in mice R Kasetti, P Patel, A Sope, G Zode Investigative Ophthalmology & Visual Science 59 (9), 3704-3704, 2018 | | 2018 |
Inhibition of chronic endoplasmic reticulum stress rescues myocilin-associated glaucoma via stimulation of autophagic flux in the TM P Maddineni, P Patel, G Zode | | 2018 |
Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma R Kasetti, P Maddineni, P Patel, JC Millar, T Phan, CC Searby, AF Clark, ... Investigative Ophthalmology & Visual Science 58 (8), 4603-4603, 2017 | | 2017 |