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Pinkal D. Patel
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Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension
RB Kasetti, P Maddineni, PD Patel, C Searby, VC Sheffield, GS Zode
Journal of Biological Chemistry 293 (25), 9854-9868, 2018
792018
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma
P Maddineni, RB Kasetti, PD Patel, JC Millar, C Kiehlbauch, AF Clark, ...
Molecular neurodegeneration 15 (1), 1-20, 2020
572020
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load
RB Kasetti, PD Patel, P Maddineni, S Patil, C Kiehlbauch, JC Millar, ...
Nature communications 11 (1), 1-14, 2020
502020
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
PD Patel, YL Chen, RB Kasetti, P Maddineni, W Mayhew, JC Millar, ...
Proceedings of the National Academy of Sciences 118 (16), e2022461118, 2021
372021
Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa
AA Rowe, PD Patel, R Gordillo, KJ Wert
JCI insight 6 (17), 2021
192021
Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork
RB Kasetti, PD Patel, P Maddineni, GS Zode
PloS one 15 (6), e0232111, 2020
162020
Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments
PD Patel, RB Kasetti, SK Sonkusare, GS Zode
Molecular vision 26, 434, 2020
22020
Inhibition of chronic endoplasmic reticulum stress rescues myocilin-associated glaucoma via stimulation of autophagic flux in the TM
R Kasetti, P Patel, G Zode
Investigative Ophthalmology & Visual Science 59 (9), 6035-6035, 2018
12018
Correction: Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork
RB Kasetti, PD Patel, P Maddineni, GS Zode
Plos one 15 (8), e0238408, 2020
2020
Impaired TRPV4-eNOS signaling in glaucomatous trabecular meshwork contributes to elevation of intraocular pressure
P Patel, R Kasetti, P Maddineni, JC Millar, YL Chen, SK Sonkusare, ...
Investigative Ophthalmology & Visual Science 61 (7), 2784-2784, 2020
2020
Increased expression of the chronic ER stress-induced transcriptional factor, ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load
R Kasetti, P Patel, P Maddineni, S Patil, C Kiehlbauch, JC Millar, ...
Investigative Ophthalmology & Visual Science 61 (7), 1236-1236, 2020
2020
The Role of Mechanosensory TRPV4 Channels and Nitric Oxide Signaling in Intraocular Pressure Homeostasis, and Its Impairment in Glaucoma
P Patel
University of North Texas Health Science Center at Fort Worth, 2020
2020
Glucocorticoid-induced glaucomatous neurodegeneration is associated with demyelination of optic nerve axons and infiltration of immune cells.
R Kasetti, PD Patel, G Zode
Investigative Ophthalmology & Visual Science 60 (9), 683-683, 2019
2019
Ex-vivo cultured human anterior segment model to study the effects of glaucoma factors on trabecular meshwork
R Kasetti, PD Patel, G Zode
Investigative Ophthalmology & Visual Science 60 (9), 5160-5160, 2019
2019
Activation of TRPV4 channels reduces IOP and improves outflow facility by regulating eNOS dependent NO release from the TM
PD Patel, R Kasetti, JC Millar, G Zode
Investigative Ophthalmology & Visual Science 60 (9), 6473-6473, 2019
2019
Increased expression of ATF4 in trabecular meshwork elevates IOP and leads to glaucomatous neurodegeneration by increasing secretory protein load of the endoplasmic reticulum
G Zode, R Kasetti, PD Patel, V Sheffield
Investigative Ophthalmology & Visual Science 60 (9), 5215-5215, 2019
2019
TRPV4-mediated regulation of intraocular pressure and outflow facility in mouse model of glucocorticoid-induced ocular hypertension
P Patel, JC Millar, R Kasetti, G Zode
Investigative Ophthalmology & Visual Science 59 (9), 4728-4728, 2018
2018
Glucocorticoid-induced ocular hypertension leads to progressive retinal ganglion cell loss, impaired axonal transport and optic nerve degeneration in mice
R Kasetti, P Patel, A Sope, G Zode
Investigative Ophthalmology & Visual Science 59 (9), 3704-3704, 2018
2018
Inhibition of chronic endoplasmic reticulum stress rescues myocilin-associated glaucoma via stimulation of autophagic flux in the TM
P Maddineni, P Patel, G Zode
2018
Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma
R Kasetti, P Maddineni, P Patel, JC Millar, T Phan, CC Searby, AF Clark, ...
Investigative Ophthalmology & Visual Science 58 (8), 4603-4603, 2017
2017
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