The increased trafficking of the calcium channel subunit α2δ-1 to presynaptic terminals in neuropathic pain is inhibited by the α2δ ligand pregabalin CS Bauer, M Nieto-Rostro, W Rahman, A Tran-Van-Minh, L Ferron, ... Journal of Neuroscience 29 (13), 4076-4088, 2009 | 510 | 2009 |
The α2δ subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function A Davies, I Kadurin, A Alvarez-Laviada, L Douglas, M Nieto-Rostro, ... Proceedings of the National Academy of Sciences 107 (4), 1654-1659, 2010 | 305 | 2010 |
Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses Z Huang, R Lujan, I Kadurin, VN Uebele, JJ Renger, AC Dolphin, ... Nature neuroscience 14 (4), 478-486, 2011 | 206 | 2011 |
Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits JS Cassidy, L Ferron, I Kadurin, WS Pratt, AC Dolphin Proceedings of the National Academy of Sciences 111 (24), 8979-8984, 2014 | 153 | 2014 |
A new look at calcium channel α2δ subunits CS Bauer, A Tran-Van-Minh, I Kadurin, AC Dolphin Current opinion in neurobiology 20 (5), 563-571, 2010 | 122 | 2010 |
Strong modulation by RFamide neuropeptides of the ASIC1b/3 heteromer in competition with extracellular calcium X Chen, M Paukert, I Kadurin, M Pusch, S Gründer Neuropharmacology 50 (8), 964-974, 2006 | 62 | 2006 |
Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels I Kadurin, L Ferron, SW Rothwell, JO Meyer, LR Douglas, CS Bauer, ... Elife 5, e21143, 2016 | 59 | 2016 |
Calcium currents are enhanced by α2δ-1 lacking its membrane anchor I Kadurin, A Alvarez-Laviada, SFJ Ng, R Walker-Gray, M D'Arco, ... Journal of Biological Chemistry 287 (40), 33554-33566, 2012 | 52 | 2012 |
LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit I Kadurin, SW Rothwell, B Lana, M Nieto-Rostro, AC Dolphin Scientific reports 7 (1), 43802, 2017 | 48 | 2017 |
Zebrafish acid-sensing ion channel (ASIC) 4, characterization of homo-and heteromeric channels, and identification of regions important for activation by H+ X Chen, G Polleichtner, I Kadurin, S Grunder Journal of Biological Chemistry 282 (42), 30406-30413, 2007 | 47 | 2007 |
The α2δ-like protein Cachd1 increases N-type calcium currents and cell surface expression and competes with α2δ-1 S Dahimene, KM Page, I Kadurin, L Ferron, DY Ho, GT Powell, WS Pratt, ... Cell reports 25 (6), 1610-1621. e5, 2018 | 46 | 2018 |
Thrombospondin-4 reduces binding affinity of [3H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co … B Lana, KM Page, I Kadurin, S Ho, M Nieto-Rostro, AC Dolphin Scientific reports 6 (1), 24531, 2016 | 45 | 2016 |
Proteolytic maturation of α2δ controls the probability of synaptic vesicular release L Ferron, I Kadurin, AC Dolphin Elife 7, e37507, 2018 | 37 | 2018 |
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b I Kadurin, A Golubovic, L Leisle, H Schindelin, S Gründer Biochemical Journal 412 (3), 469-475, 2008 | 36 | 2008 |
A single conserved proline residue determines the membrane topology of stomatin I Kadurin, S Huber, S Gründer Biochemical Journal 418 (3), 587-594, 2009 | 34 | 2009 |
Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy S Dahimene, L von Elsner, T Holling, LS Mattas, J Pickard, D Lessel, ... Brain 145 (8), 2721-2729, 2022 | 25 | 2022 |
Disruption of the key Ca2+ binding site in the selectivity filter of neuronal voltage-gated calcium channels inhibits channel trafficking JO Meyer, S Dahimene, KM Page, L Ferron, I Kadurin, JIJ Ellaway, ... Cell reports 29 (1), 22-33. e5, 2019 | 22 | 2019 |
The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways A Alvarez-Laviada, I Kadurin, A Senatore, R Chiesa, AC Dolphin Biochemical Journal 458 (2), 365-374, 2014 | 17 | 2014 |
ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α2δ Subunits, and Enables Calcium Current Enhancement I Kadurin, S Dahimene, KM Page, JIJ Ellaway, K Chaggar, L Troeberg, ... Function 3 (3), zqac013, 2022 | 6 | 2022 |
Fight or flight: The culprit is lurking in the neighbourhood AC Dolphin, I Kadurin Cell Calcium 87, 102180, 2020 | 4 | 2020 |