Histone deacetylase inhibitors: from bench to clinic M Paris, M Porcelloni, M Binaschi, D Fattori Journal of medicinal chemistry 51 (6), 1505-1529, 2008 | 471 | 2008 |
Anthracyclines: selected new developments M Binaschi, M Bigioni, A Cipollone, C Rossi, C Goso, CA Maggi, ... Current Medicinal Chemistry-Anti-Cancer Agents 1 (2), 113-130, 2001 | 287 | 2001 |
DNA sequence selectivity of topoisomerases and topoisomerase poisons G Capranico, M Binaschi Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1400 (1-3 …, 1998 | 178 | 1998 |
MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer T Colangelo, A Fucci, C Votino, L Sabatino, M Pancione, C Laudanna, ... Neoplasia 15 (9), 1086-1099, 2013 | 165 | 2013 |
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons G Capranico, M Binaschi, ME Borgnetto, F Zunino, M Palumbo Trends in Pharmacological Sciences 18 (9), 323-329, 1997 | 137 | 1997 |
Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity M Binaschi, G Capranico, L Dal Bo, F Zunino Molecular pharmacology 51 (6), 1053-1059, 1997 | 129 | 1997 |
Topoisomerase poisoning activity of novel disaccharide anthracyclines F Guano, P Pourquier, S Tinelli, M Binaschi, M Bigioni, F Animati, ... Molecular Pharmacology 56 (1), 77-84, 1999 | 112 | 1999 |
Mechanism of action of DNA topoisomerase inhibitors M Binaschi, F Zunino, G Capranico Stem Cells 13 (4), 369-379, 1995 | 104 | 1995 |
Antiproliferative and differentiating activities of a novel series of histone deacetylase inhibitors M Binaschi, A Boldetti, M Gianni, CA Maggi, M Gensini, M Bigioni, ... ACS Medicinal Chemistry Letters 1 (8), 411-415, 2010 | 92 | 2010 |
Influence of structural modifications at the 3'and 4'positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance. G Capranico, R Supino, M Binaschi, L Capolongo, M Grandi, A Suarato, ... Molecular pharmacology 45 (5), 908-915, 1994 | 91 | 1994 |
Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer T Colangelo, G Polcaro, P Ziccardi, B Pucci, L Muccillo, M Galgani, ... Cell death & disease 7 (2), e2120-e2120, 2016 | 81 | 2016 |
CD137 and CD137 ligand constitutively coexpressed on human T and B leukemia cells signal proliferation and survival C Palma, M Binaschi, M Bigioni, CA Maggi, C Goso International journal of cancer 108 (3), 390-398, 2004 | 70 | 2004 |
MRP gene overexpression in a human doxorubicin‐resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross‐resistance M Binaschi, R Supino, RA Gambetta, G Giaccone, E Prosperi, ... International journal of cancer 62 (1), 84-89, 1995 | 68 | 1995 |
In vivo site specificity and human isoenzyme selectivity of two topoisomerase II-poisoning anthracyclines M Binaschi, R Farinosi, ME Borgnetto, G Capranico Cancer research 60 (14), 3770-3776, 2000 | 63 | 2000 |
Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small‐cell lung cancer lines with different sensitivities to topoisomerase II inhibitors M Binaschi, G Capranico, P De Isabella, M Mariani, R Supino, S Tinelli, ... International journal of cancer 45 (2), 347-352, 1990 | 63 | 1990 |
Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells. P De Isabella, G Capranico, M Binaschi, S Tinelli, F Zunino Molecular Pharmacology 37 (1), 11-16, 1990 | 62 | 1990 |
Novel anthracycline oligosaccharides: influence of chemical modifications of the carbohydrate moiety on biological activity A Cipollone, M Berettoni, M Bigioni, M Binaschi, C Cermele, ... Bioorganic & medicinal chemistry 10 (5), 1459-1470, 2002 | 51 | 2002 |
NF-κB activation contributes to anthracycline resistance pathway in human ovarian carcinoma cell line A2780 C Salvatore, G Camarda, CA Maggi, C Goso, S Manzini, M Binaschi International journal of oncology 27 (3), 799-806, 2005 | 50 | 2005 |
Irreversible and reversible topoisomerase II DNA cleavage stimulated by clerocidin: sequence specificity and structural drug determinants M Binaschi, G Zagotto, M Palumbo, F Zunino, R Farinosi, G Capranico Cancer research 57 (9), 1710-1716, 1997 | 43 | 1997 |
OC125, M11 and OV197 epitopes are not uniformly distributed in the tandem-repeat region of CA125 and require the entire SEA domain A Bressan, F Bozzo, CA Maggi, M Binaschi Disease markers 34 (4), 257-267, 2013 | 39 | 2013 |