| Development of a new benzophenone–diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure Y Hayashi, H Takeno, T Chinen, K Muguruma, K Okuyama, A Taguchi, ... ACS Medicinal Chemistry Letters 5 (10), 1094-1098, 2014 | 46 | 2014 |
| 3‐Nitro‐2‐pyridinesulfenates as efficient solution‐and solid‐phase disulfide bond forming agents A Taguchi, K Kobayashi, A Kotani, K Muguruma, M Kobayashi, ... Chemistry–A European Journal 23 (34), 8262-8267, 2017 | 29 | 2017 |
| Novel Hybrid Compound of a Plinabulin Prodrug with an IgG Binding Peptide for Generating a Tumor Selective Noncovalent-Type Antibody–Drug Conjugate K Muguruma, F Yakushiji, R Kawamata, D Akiyama, R Arima, T Shirasaka, ... Bioconjugate Chemistry 27 (7), 1606-1613, 2016 | 28 | 2016 |
| Development of potent myostatin inhibitory peptides through hydrophobic residue-directed structural modification K Takayama, C Rentier, T Asari, A Nakamura, Y Saga, T Shimada, ... ACS medicinal chemistry letters 8 (7), 751-756, 2017 | 24 | 2017 |
| Targeted 1, 3-dipolar cycloaddition with acrolein for cancer prodrug activation AR Pradipta, P Ahmadi, K Terashima, K Muguruma, M Fujii, T Ichino, ... Chemical Science 12 (15), 5438-5449, 2021 | 23 | 2021 |
| Water‐Soluble Prodrug of Antimicrotubule Agent Plinabulin: Effective Strategy with Click Chemistry F Yakushiji, H Tanaka, K Muguruma, T Iwahashi, Y Yamazaki, Y Hayashi Chemistry–A European Journal 45 (17), 12587-12590, 2011 | 23 | 2011 |
| Disease-associated acrolein: A possible diagnostic and therapeutic substrate for in vivo synthetic chemistry K Muguruma, AR Pradipta, Y Ode, K Terashima, H Michiba, M Fujii, ... Bioorganic & Medicinal Chemistry 28 (24), 115831, 2020 | 21 | 2020 |
| In vivo metal-catalyzed SeCT therapy by a proapoptotic peptide P Ahmadi, K Muguruma, TC Chang, S Tamura, K Tsubokura, Y Egawa, ... Chemical Science 12 (37), 12266-12273, 2021 | 16 | 2021 |
| An Efficient Method for the Conjugation of Hydrophilic and Hydrophobic Components by Solid‐Phase‐Assisted Disulfide Ligation K Muguruma, T Shirasaka, D Akiyama, K Fukumoto, A Taguchi, ... Angewandte Chemie 130 (8), 2192-2195, 2018 | 14 | 2018 |
| “On‐Resin” Disulfide Peptide Synthesis with Methyl 3‐Nitro‐2‐pyridinesulfenate K Kobayashi, A Taguchi, Y Cui, H Shida, K Muguruma, K Takayama, ... European Journal of Organic Chemistry 2021 (6), 956-963, 2021 | 12 | 2021 |
| Prodrug study of plinabulin using a click strategy focused on the effects of a replaceable water-solubilizing moiety F Yakushiji, H Tanaka, K Muguruma, T Iwahashi, Y Yamazaki, Y Hayashi Chemical and Pharmaceutical Bulletin 60 (7), 877-881, 2012 | 11 | 2012 |
| Kinetics-based structural requirements of human immunoglobulin G binding peptides K Muguruma, K Fujita, A Fukuda, S Kishimoto, S Sakamoto, R Arima, M Ito, ... ACS omega 4 (11), 14390-14397, 2019 | 9 | 2019 |
| Therapeutic efficacy of 211 At-radiolabeled 2, 6-diisopropylphenyl azide in mouse models of human lung cancer Y Ode, AR Pradipta, P Ahmadi, A Ishiwata, A Nakamura, Y Egawa, ... Chemical Science 14 (30), 8054-8060, 2023 | 8 | 2023 |
| Structural revision of natural cyclic depsipeptide MA026 established by total synthesis and biosynthetic gene cluster analysis C Uchiyama, A Fukuda, M Mukaiyama, Y Nakazawa, Y Kuramochi, ... Angewandte Chemie International Edition 60 (16), 8792-8797, 2021 | 8 | 2021 |
| Click strategy using disodium salts of amino acids improves the water solubility of plinabulin and KPU-300 F Yakushiji, K Muguruma, Y Hayashi, T Shirasaka, R Kawamata, ... Bioorganic & Medicinal Chemistry 25 (14), 3623-3630, 2017 | 7 | 2017 |
| Development of a High‐Affinity Antibody‐Binding Peptide for Site‐Specific Modification K Muguruma, R Osawa, A Fukuda, N Ishikawa, K Fujita, A Taguchi, ... ChemMedChem 16 (11), 1814-1821, 2021 | 6 | 2021 |
| Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy K Sasaki, K Muguruma, R Osawa, A Fukuda, A Taniguchi, A Kishimura, ... RSC Medicinal Chemistry 12 (3), 406-409, 2021 | 5 | 2021 |
| Evaluation of acute toxicity of cancer-targeting albumin-based artificial metalloenzymes TC Chang, I Nasibullin, K Muguruma, Y Kusakari, T Shimoda, K Tanaka Bioorganic & Medicinal Chemistry 73, 117005, 2022 | 4 | 2022 |
| O-Alkyl S-(Pyridin-2-yl) carbonothiolates: Operationally Simple and Highly Nitrogen-Selective Reagents for Alkoxy Carbonylation of Amino Groups T Suzuki, K Tanaka III, Y Hashimoto, N Morita, O Tamura Synlett 31 (09), 899-902, 2020 | 4 | 2020 |
| Synthesis and structure–activity relationship studies of IgG-binding peptides focused on the C-terminal histidine residue K Muguruma, M Ito, A Fukuda, S Kishimoto, A Taguchi, K Takayama, ... MedChemComm 10 (10), 1789-1795, 2019 | 4 | 2019 |
