HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia HK Eltzschig, P Abdulla, E Hoffman, KE Hamilton, D Daniels, ... The Journal of experimental medicine 202 (11), 1493-1505, 2005 | 381 | 2005 |
β-Hydroxybutyrate suppresses colorectal cancer O Dmitrieva-Posocco, AC Wong, P Lundgren, AM Golos, HC Descamps, ... Nature 605 (7908), 160-165, 2022 | 176 | 2022 |
Selective induction of mucin‐3 by hypoxia in intestinal epithelia NA Louis, KE Hamilton, G Canny, LL Shekels, SB Ho, SP Colgan Journal of cellular biochemistry 99 (6), 1616-1627, 2006 | 170 | 2006 |
Inflammation and colorectal cancer AG Long, ET Lundsmith, KE Hamilton Current colorectal cancer reports 13, 341-351, 2017 | 167 | 2017 |
Loss of stromal IMP1 promotes a tumorigenic microenvironment in the colon KE Hamilton, P Chatterji, ET Lundsmith, SF Andres, V Giroux, PD Hicks, ... Molecular cancer research 13 (11), 1478-1486, 2015 | 142 | 2015 |
The esophageal organoid system reveals functional interplay between notch and cytokines in reactive epithelial changes Y Kasagi, PM Chandramouleeswaran, KA Whelan, K Tanaka, V Giroux, ... Cellular and molecular gastroenterology and hepatology 5 (3), 333-352, 2018 | 108 | 2018 |
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. RAK Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE ... J Cin Invest, 2017 | 106* | 2017 |
HIF‐dependent induction of apical CD55 coordinates epithelial clearance of neutrophils NA Louis, KE Hamilton, T Kong, SP Colgan The FASEB journal 19 (8), 950-959, 2005 | 93 | 2005 |
Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells KE Hamilton, JG Simmons, S Ding, L Van Landeghem, PK Lund Molecular Cancer Research 9 (12), 1718-1731, 2011 | 90 | 2011 |
IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts KE Hamilton, FK Noubissi, PS Katti, CM Hahn, SR Davey, ET Lundsmith, ... Carcinogenesis 34 (11), 2647-2654, 2013 | 85 | 2013 |
WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma A Long, V Giroux, KA Whelan, KE Hamilton, MP Tétreault, K Tanaka, ... Carcinogenesis 36 (5), 598-606, 2015 | 75 | 2015 |
The pediatric cell atlas: defining the growth phase of human development at single-cell resolution DM Taylor, BJ Aronow, K Tan, K Bernt, N Salomonis, CS Greene, ... Developmental cell 49 (1), 10-29, 2019 | 63 | 2019 |
Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines SA Smith, SA Ogawa, L Chau, KA Whelan, KE Hamilton, J Chen, L Tan, ... The Journal of clinical investigation 131 (1), 2021 | 62 | 2021 |
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis KA Whelan, JF Merves, V Giroux, K Tanaka, A Guo, ... Gut 66 (7), 1197-1207, 2017 | 55 | 2017 |
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1. FMR Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB ... Cell Death Differ., 2017 | 38 | 2017 |
Mouse intestinal Krt15+ crypt cells are radio-resistant and tumor initiating V Giroux, J Stephan, P Chatterji, B Rhoades, EP Wileyto, AJ Klein-Szanto, ... Stem cell reports 10 (6), 1947-1958, 2018 | 37 | 2018 |
Geometric engineering of organoid culture for enhanced organogenesis in a dish SE Park, S Kang, J Paek, A Georgescu, J Chang, AY Yi, BJ Wilkins, ... Nature methods 19 (11), 1449-1460, 2022 | 34 | 2022 |
Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer TA Karakasheva, JT Gabre, UM Sachdeva, R Cruz-Acuña, EW Lin, ... Scientific reports 11 (1), 21304, 2021 | 34 | 2021 |
Autophagy as a cytoprotective mechanism in esophageal squamous cell carcinoma TM Hall, MP Tétreault, KE Hamilton, KA Whelan Current opinion in pharmacology 41, 12-19, 2018 | 30 | 2018 |
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP 1/IGF 2 BP 1 P Chatterji, PA Williams, KA Whelan, FC Samper, SF Andres, LA Simon, ... EMBO reports 20 (6), e47074, 2019 | 28 | 2019 |