| Ceramide-orchestrated signalling in cancer cells SAF Morad, MC Cabot Nature Reviews Cancer 13 (1), 51-65, 2013 | 697 | 2013 |
| Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells AC Estrada, T Syrovets, K Pitterle, O Lunov, B Büchele, ... Molecular Pharmacology 77 (3), 378-387, 2010 | 108 | 2010 |
| Acid ceramidase is upregulated in AML and represents a novel therapeutic target SF Tan, X Liu, TE Fox, BM Barth, A Sharma, SD Turner, A Awwad, ... Oncotarget 7 (50), 83208, 2016 | 82 | 2016 |
| Tamoxifen regulation of sphingolipid metabolism—therapeutic implications SAF Morad, MC Cabot Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 75 | 2015 |
| Novel off-target effect of tamoxifen—inhibition of acid ceramidase activity in cancer cells SAF Morad, JC Levin, SF Tan, TE Fox, DJ Feith, MC Cabot Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 74 | 2013 |
| Ceramide–antiestrogen nanoliposomal combinations—novel impact of hormonal therapy in hormone-insensitive breast cancer SAF Morad, JC Levin, SS Shanmugavelandy, M Kester, G Fabrias, ... Molecular cancer therapeutics 11 (11), 2352-2361, 2012 | 54 | 2012 |
| Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53 SAF Morad, JP Madigan, JC Levin, N Abdelmageed, R Karimi, ... Biochemical pharmacology 85 (8), 1057-1065, 2013 | 49 | 2013 |
| A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells SAF Morad, M Schmid, B Büchele, HU Siehl, M El Gaafary, O Lunov, ... Molecular pharmacology 83 (2), 531-541, 2013 | 46 | 2013 |
| Gaucher's disease and cancer: a sphingolipid perspective BM Barth, SS Shanmugavelandy, DM Tacelosky, M Kester, SAF Morad, ... Critical Reviews™ in Oncogenesis 18 (3), 2013 | 39 | 2013 |
| Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation SF Tan, W Dunton, X Liu, TE Fox, SAF Morad, D Desai, K Doi, ... Journal of lipid research 60 (6), 1078-1086, 2019 | 35 | 2019 |
| Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia1 SAF Morad, TE Ryan, PD Neufer, TN Zeczycki, TS Davis, MR MacDougall, ... Journal of lipid research 57 (7), 1231-1242, 2016 | 31 | 2016 |
| Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells SAF Morad, MC Messner, JC Levin, N Abdelmageed, H Park, AH Merrill, ... Cancer chemotherapy and pharmacology 71, 635-645, 2013 | 31 | 2013 |
| Bioactive sphingolipids in cancer biology and therapy YA Hannun, C Luberto, C Mao, LM Obeid Springer International Publishing, 2015 | 30 | 2015 |
| Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia—impact on enzyme activity and response to cytotoxics SAF Morad, SF Tan, DJ Feith, M Kester, DF Claxton, TP Loughran Jr, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 30 | 2015 |
| (8 R)-3β, 8-Dihydroxypolypoda-13 E, 17 E, 21-triene Induces Cell Cycle Arrest and Apoptosis in Treatment-Resistant Prostate Cancer Cells SAF Morad, C Schmidt, B Büchele, B Schneider, M Wenzler, T Syrovets, ... Journal of natural products 74 (8), 1731-1736, 2011 | 30 | 2011 |
| Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells LP Kao, SAF Morad, TS Davis, MR MacDougall, M Kassai, ... Journal of lipid research 60 (9), 1590-1602, 2019 | 25 | 2019 |
| Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer SAF Morad, TS Davis, MR MacDougall, SF Tan, DJ Feith, DH Desai, ... Biochemical pharmacology 130, 21-33, 2017 | 25 | 2017 |
| Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells N Abdelmageed, SAF Morad, AA Elghoneimy, T Syrovets, T Simmet, ... Biomedicine & Pharmacotherapy 96, 417-425, 2017 | 23 | 2017 |
| The onus of sphingolipid enzymes in cancer drug resistance SAF Morad, MC Cabot Advances in Cancer Research 140, 235-263, 2018 | 20 | 2018 |
| Short-chain ceramides depress integrin cell surface expression and function in colorectal cancer cells SAF Morad, LC Bridges, ADA Larrea, AL Mayen, MR MacDougall, ... Cancer letters 376 (2), 199-204, 2016 | 20 | 2016 |
