| Distinct routes of lineage development reshape the human blood hierarchy across ontogeny F Notta, S Zandi, N Takayama, S Dobson, OI Gan, G Wilson, ... Science 351 (6269), aab2116, 2016 | 854 | 2016 |
| Gene therapy on the move KB Kaufmann, H Büning, A Galy, A Schambach, M Grez EMBO molecular medicine 5 (11), 1642-1661, 2013 | 362 | 2013 |
| Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment A Ludin, S Gur-Cohen, K Golan, KB Kaufmann, T Itkin, C Medaglia, XJ Lu, ... Antioxidants & redox signaling 21 (11), 1605-1619, 2014 | 308 | 2014 |
| Deregulation of DUX4 and ERG in acute lymphoblastic leukemia J Zhang, K McCastlain, H Yoshihara, B Xu, Y Chang, ML Churchman, ... Nature genetics 48 (12), 1481-1489, 2016 | 292 | 2016 |
| miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ... Cancer cell 29 (2), 214-228, 2016 | 289 | 2016 |
| Sphingolipid modulation activates proteostasis programs to govern human hematopoietic stem cell self-renewal SZ Xie, L Garcia-Prat, V Voisin, R Ferrari, OI Gan, E Wagenblast, ... Cell stem cell 25 (5), 639-653. e7, 2019 | 89 | 2019 |
| TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate L García-Prat, KB Kaufmann, F Schneiter, V Voisin, A Murison, J Chen, ... Cell stem cell 28 (10), 1838-1850. e10, 2021 | 86 | 2021 |
| Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity JD Suerth, T Maetzig, MH Brugman, N Heinz, JU Appelt, KB Kaufmann, ... Molecular therapy 20 (5), 1022-1032, 2012 | 81 | 2012 |
| The transition from quiescent to activated states in human hematopoietic stem cells is governed by dynamic 3D genome reorganization N Takayama, A Murison, S Takayanagi, C Arlidge, S Zhou, L Garcia-Prat, ... Cell stem cell 28 (3), 488-501. e10, 2021 | 58 | 2021 |
| T cells engineered with a cytomegalovirus-specific chimeric immunoreceptor F Full, M Lehner, V Thonn, G Goetz, B Scholz, KB Kaufmann, M Mach, ... Journal of virology 84 (8), 4083-4088, 2010 | 55 | 2010 |
| Surface functionalization of orthopedic titanium implants with bone sialoprotein A Baranowski, A Klein, U Ritz, A Ackermann, J Anthonissen, ... PLoS One 11 (4), e0153978, 2016 | 49 | 2016 |
| Fibroblast growth factor signaling promotes physiological bone remodeling and stem cell self-renewal T Itkin, KB Kaufmann, S Gur-Cohen, A Ludin, T Lapidot Current opinion in hematology 20 (3), 237-244, 2013 | 41 | 2013 |
| Adenovirus L4-22K stimulates major late transcription by a mechanism requiring the intragenic late-specific transcription factor-binding site E Backström, KB Kaufmann, X Lan, G Akusjärvi Virus research 151 (2), 220-228, 2010 | 39 | 2010 |
| A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness KB Kaufmann, AGX Zeng, E Coyaud, L Garcia-Prat, E Papalexi, ... Nature immunology 22 (6), 723-734, 2021 | 38 | 2021 |
| The effect of different collagen modifications for titanium and titanium nitrite surfaces on functions of gingival fibroblasts U Ritz, T Nusselt, A Sewing, T Ziebart, K Kaufmann, A Baranowski, ... Clinical oral investigations 21, 255-265, 2017 | 38 | 2017 |
| Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing KB Kaufmann, C Brendel, JD Suerth, U Mueller-Kuller, L Chen-Wichmann, ... Molecular Therapy 21 (3), 648-661, 2013 | 38 | 2013 |
| Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation SZ Xie, KB Kaufmann, W Wang, M Chan-Seng-Yue, OI Gan, E Laurenti, ... Blood Cancer Discovery, 2020 | 37 | 2020 |
| CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells C Brendel, B Goebel, A Daniela, M Brugman, S Kneissl, J Schwäble, ... Molecular Therapy 23 (1), 63-70, 2015 | 36 | 2015 |
| The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness GE Thomas, G Egan, L García-Prat, A Botham, V Voisin, PS Patel, ... Nature cell biology 24 (6), 872-884, 2022 | 35 | 2022 |
| From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease S Stein, S Scholz, J Schwäble, MA Sadat, U Modlich, S Schultze-Strasser, ... Human Gene Therapy Clinical Development 24 (2), 86-98, 2013 | 34 | 2013 |
