GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability WL Hu, L Jin, AN Xu, YF Wang, RF Thorne, XD Zhang, M Wu Nature cell biology 20 (4), 492-502, 2018 | 270 | 2018 |
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism H Kim, S Yoo, R Zhou, A Xu, JM Bernitz, Y Yuan, AM Gomes, MG Daniel, ... Proceedings of the National Academy of Sciences 115 (47), E11128-E11137, 2018 | 54 | 2018 |
Li–Fraumeni syndrome disease model: a platform to develop precision cancer therapy targeting oncogenic p53 R Zhou, A Xu, J Gingold, LC Strong, R Zhao, DF Lee Trends in pharmacological sciences 38 (10), 908-927, 2017 | 50 | 2017 |
BECN1s, a short splice variant of BECN1, functions in mitophagy B Cheng, A Xu, M Qiao, Q Wu, W Wang, Y Mei, M Wu Autophagy 11 (11), 2048-2056, 2015 | 30 | 2015 |
Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies J Tu, Z Huo, Y Yu, D Zhu, A Xu, MF Huang, R Hu, R Wang, JA Gingold, ... Proceedings of the National Academy of Sciences 119 (16), e2117857119, 2022 | 20 | 2022 |
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome BE Jewell, A Xu, D Zhu, MF Huang, L Lu, M Liu, EL Underwood, JH Park, ... PLoS Genetics 17 (12), e1009971, 2021 | 14 | 2021 |
Modeling osteosarcoma using Li-fraumeni syndrome patient-derived induced pluripotent stem cells R Zhou, A Xu, J Tu, M Liu, JA Gingold, R Zhao, DF Lee JoVE (Journal of Visualized Experiments), e57664, 2018 | 14 | 2018 |
LncRNA H19 suppresses osteosarcomagenesis by regulating snoRNAs and DNA repair protein complexes DF Lee, A Xu, MF Huang, D Zhu, JA Gingold, B Chang, D Wang, CC Lai, ... Frontiers in Genetics 11, 1773, 2020 | 13 | 2020 |
Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase J Tu, Z Huo, M Liu, D Wang, A Xu, R Zhou, D Zhu, J Gingold, J Shen, ... Stem cell research 28, 29-32, 2018 | 13 | 2018 |
RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III–dependent transcription F Wang, K Zhao, S Yu, A Xu, W Han, Y Mei Journal of Biological Chemistry 294 (1), 130-141, 2019 | 12 | 2019 |
Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing Z Huo, J Tu, A Xu, Y Li, D Wang, M Liu, R Zhou, D Zhu, Y Lin, JA Gingold, ... Stem cell research 34, 101360, 2019 | 12 | 2019 |
Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing A Xu, R Zhou, J Tu, Z Huo, D Zhu, D Wang, JA Gingold, H Mata, PH Rao, ... Stem cell research 29, 215-219, 2018 | 10 | 2018 |
A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing R Zhou, A Xu, D Wang, D Zhu, H Mata, Z Huo, J Tu, M Liu, AMT Mohamed, ... Stem cell research 27, 131-135, 2018 | 10 | 2018 |
Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation A Xu, M Liu, MF Huang, Y Zhang, R Hu, JA Gingold, Y Liu, D Zhu, ... Nature Communications 14 (1), 1694, 2023 | 7 | 2023 |
Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death JH Choe, T Kawase, A Xu, A Guzman, AZ Obradovic, AM Low-Calle, ... Cancer Discovery, OF1-OF24, 2023 | 6 | 2023 |
Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1 PS Huang, MH Wen, X Xie, A Xu, DF Lee, TY Chen Stem cell research 54, 102415, 2021 | 5 | 2021 |
Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation BE Jewell, M Liu, L Lu, R Zhou, J Tu, D Zhu, Z Huo, A Xu, D Wang, H Mata, ... Stem cell research 33, 36-40, 2018 | 3 | 2018 |
Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants D Chachad, LR Patel, CV Recio, R Pourebrahim, EM Whitley, W Wang, ... Cancer Research, CAN-22-3464, 2023 | 2 | 2023 |
Systematic Transcriptome Profiling of hPSC-derived Osteoblasts Unveils CORIN's Mastery in Governing Osteogenesis Through CEBPD Modulation D Zhu, MF Huang, A Xu, X Gao, YW Huang, TTT Phan, L Lu, TY Chi, ... Journal of Biological Chemistry, 107494, 2024 | | 2024 |