Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus F Di Nicolantonio, S Arena, J Tabernero, S Grosso, F Molinari, ... The Journal of clinical investigation 120 (8), 2858-2866, 2010 | 403 | 2010 |
Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model S Ricciardi, EM Boggio, S Grosso, G Lonetti, G Forlani, G Stefanelli, ... Human molecular genetics 20 (6), 1182-1196, 2011 | 252 | 2011 |
Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf) T Chernova, FA Murphy, S Galavotti, XM Sun, IR Powley, S Grosso, ... Current Biology 27 (21), 3302-3314. e6, 2017 | 122 | 2017 |
Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth A Miluzio, A Beugnet, S Grosso, D Brina, M Mancino, S Campaner, ... Cancer Cell 19 (6), 765-775, 2011 | 103 | 2011 |
Control of translation elongation in health and disease JRP Knight, G Garland, T Pöyry, E Mead, N Vlahov, A Sfakianos, ... Disease models & mechanisms 13 (3), dmm043208, 2020 | 81 | 2020 |
RTN3 is a novel cold-induced protein and mediates neuroprotective effects of RBM3 A Bastide, D Peretti, JRP Knight, S Grosso, RV Spriggs, X Pichon, ... Current Biology 27 (5), 638-650, 2017 | 73 | 2017 |
PKCβII modulates translation independently from mTOR and through RACK1 S Grosso, V Volta, LA Sala, M Vietri, PC Marchisio, D Ron, S Biffo Biochemical Journal 415 (1), 77-85, 2008 | 71 | 2008 |
Translational control by 80S formation and 60S availability: The central role of eIF6, a rate limiting factor in cell cycle progression and tumorigenesis D Brina, S Grosso, A Miluzio, S Biffo Cell Cycle 10 (20), 3441-3446, 2011 | 58 | 2011 |
Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease T Chernova, XM Sun, IR Powley, S Galavotti, S Grosso, FA Murphy, ... Cell Death & Differentiation 23 (7), 1152-1164, 2016 | 52 | 2016 |
Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo A Miluzio, S Oliveto, E Pesce, L Mutti, B Murer, S Grosso, S Ricciardi, ... Oncotarget 6 (35), 37471, 2015 | 44 | 2015 |
A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma S Oliveto, R Alfieri, A Miluzio, A Scagliola, RS Secli, P Gasparini, ... Cancer research 78 (20), 5741-5753, 2018 | 31 | 2018 |
The pathogenesis of mesothelioma is driven by a dysregulated translatome S Grosso, A Marini, K Gyuraszova, JV Voorde, A Sfakianos, GD Garland, ... Nature Communications 12 (1), 4920, 2021 | 30 | 2021 |
Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1 S Grosso, E Pesce, D Brina, A Beugnet, F Loreni, S Biffo PLoS One 6 (12), e29136, 2011 | 23 | 2011 |
Eukaryotic ribosomes host PKC activity S Grosso, V Volta, M Vietri, C Gorrini, PC Marchisio, S Biffo Biochemical and biophysical research communications 376 (1), 65-69, 2008 | 22 | 2008 |
Spreading of mesothelioma cells is rapamycin‐sensitive and requires continuing translation E Ranzato, S Grosso, M Patrone, PG Betta, A Viarengo, S Biffo Journal of cellular biochemistry 108 (4), 867-876, 2009 | 11 | 2009 |
Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells T Chernova, S Grosso, XM Sun, AR Tenor, JZ Cabeza, A Craxton, EL Self, ... International Journal of Molecular Sciences 23 (20), 12469, 2022 | 5 | 2022 |
Cap dependent translation contributes to resistance of myeloma cells to bortezomib M Mancino, S Grosso, C Terragna, E Borsi, M Cavo, S Biffo Translation 1 (2), e27245, 2013 | 4 | 2013 |
Targeting the rate limiting step of protein synthesis may provide an alternative approach to overcome the chemoresistance of malignant mesothelioma S Grosso, GM George, T Chernova, XM Sun, FA Murphy, T Sbarrato, ... Toxicology Letters, S226, 2014 | | 2014 |
Mesothelioma cell spreading is rapamycin-sensitive and requires mTOR-independent ongoing translation E Ranzato, S Grosso, M Patrone, PG BETTA, AG Viarengo, S Biffo JOURNAL OF CELLULAR BIOCHEMISTRY 108, 867-876, 2009 | | 2009 |
PKC β 2. Docks on Rack1 in ribosomes and modulates initiation of translation (Potential role in evironmental stress). S Grosso Università degli Studi del Piemonte orientale" Amedeo Avogadro", 2007 | | 2007 |