Distributing a metabolic pathway among a microbial consortium enhances production of natural products K Zhou, K Qiao, S Edgar, G Stephanopoulos Nature biotechnology 33 (4), 377-383, 2015 | 689 | 2015 |
Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism K Qiao, TM Wasylenko, K Zhou, P Xu, G Stephanopoulos Nature biotechnology 35 (2), 173-177, 2017 | 433 | 2017 |
Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals P Xu, K Qiao, WS Ahn, G Stephanopoulos Proceedings of the National Academy of Sciences 113 (39), 10848-10853, 2016 | 426 | 2016 |
Engineering lipid overproduction in the oleaginous yeast Yarrowia lipolytica K Qiao, SHI Abidi, H Liu, H Zhang, S Chakraborty, N Watson, PK Ajikumar, ... Metabolic engineering 29, 56-65, 2015 | 359 | 2015 |
Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica P Xu, K Qiao, G Stephanopoulos Biotechnology and Bioengineering 114 (7), 1521-1530, 2017 | 173 | 2017 |
Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1 K Qiao, YH Chooi, Y Tang Metabolic engineering 13 (6), 723-732, 2011 | 149 | 2011 |
Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogs H Zhou*, K Qiao*, Z Gao, JC Vederas, Y Tang Journal of Biological Chemistry 285 (53), 41412-41421, 2010 | 112 | 2010 |
Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis H Zhou, K Qiao, Z Gao, MJ Meehan, JWH Li, X Zhao, PC Dorrestein, ... Journal of the American Chemical Society 132 (13), 4530-4531, 2010 | 112 | 2010 |
Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica Y Ma, N Liu, P Greisen, J Li, K Qiao, S Huang, G Stephanopoulos Nature Communications 13 (1), 572, 2022 | 101 | 2022 |
Application of metabolic controls for the maximization of lipid production in semicontinuous fermentation J Xu, N Liu, K Qiao, S Vogg, G Stephanopoulos Proceedings of the National Academy of Sciences 114 (27), E5308-E5316, 2017 | 99 | 2017 |
Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica AM Silverman*, K Qiao*, P Xu, G Stephanopoulos Applied Microbiology and Biotechnology, 1-18, 2016 | 97 | 2016 |
A carbonate-forming Baeyer-Villiger monooxygenase Y Hu, D Dietrich, W Xu, A Patel, JAJ Thuss, J Wang, WB Yin, K Qiao, ... Nature chemical biology 10 (7), 552-554, 2014 | 93 | 2014 |
A fungal ketoreductase domain that displays substrate-dependent stereospecificity H Zhou, Z Gao, K Qiao, J Wang, JC Vederas, Y Tang Nature chemical biology 8 (4), 331-333, 2012 | 88 | 2012 |
Synergistic substrate cofeeding stimulates reductive metabolism JO Park, N Liu, KM Holinski, DF Emerson, K Qiao, BM Woolston, J Xu, ... Nature Metabolism 1 (6), 643-651, 2019 | 82 | 2019 |
13C Metabolic Flux Analysis of acetate conversion to lipids by Yarrowia lipolytica N Liu, K Qiao, G Stephanopoulos Metabolic engineering 38, 86-97, 2016 | 79 | 2016 |
Engineering of taxadiene synthase for improved selectivity and yield of a key taxol biosynthetic intermediate S Edgar, FS Li, K Qiao, JK Weng, G Stephanopoulos ACS Synthetic Biology 6 (2), 201-205, 2017 | 71 | 2017 |
Structural analysis of protein–protein interactions in type I polyketide synthases W Xu*, K Qiao*, Y Tang Critical reviews in biochemistry and molecular biology 48 (2), 98-122, 2013 | 60 | 2013 |
Mechanistic insights into taxadiene epoxidation by taxadiene-5α-hydroxylase S Edgar, K Zhou, K Qiao, JR King, JH Simpson, G Stephanopoulos ACS chemical biology 11 (2), 460-469, 2016 | 59 | 2016 |
Accessing Nature’s diversity through metabolic engineering and synthetic biology JR King, S Edgar, K Qiao, G Stephanopoulos F1000Research 5, 2016 | 58 | 2016 |
Biosynthesis of poly (glycolate-co-lactate-co-3-hydroxybutyrate) from glucose by metabolically engineered Escherichia coli ZJ Li, K Qiao, W Shi, B Pereira, H Zhang, BD Olsen, G Stephanopoulos Metabolic engineering 35, 1-8, 2016 | 49 | 2016 |