Amino acid transporters in cancer and their relevance to “glutamine addiction”: novel targets for the design of a new class of anticancer drugs YD Bhutia, E Babu, S Ramachandran, V Ganapathy Cancer research 75 (9), 1782-1788, 2015 | 477 | 2015 |
DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis R Pathania, S Ramachandran, S Elangovan, R Padia, P Yang, S Cinghu, ... Nature communications 6 (1), 6910, 2015 | 256 | 2015 |
SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive … S Karunakaran, S Ramachandran, V Coothankandaswamy, S Elangovan, ... Journal of Biological Chemistry 286 (36), 31830-31838, 2011 | 219 | 2011 |
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer S Elangovan, S Ramachandran, N Venkatesan, S Ananth, ... Cancer research 71 (21), 6654-6664, 2011 | 180 | 2011 |
The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment TP Brown, P Bhattacharjee, S Ramachandran, S Sivaprakasam, B Ristic, ... Oncogene 39 (16), 3292-3304, 2020 | 173 | 2020 |
Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth R Pathania, S Ramachandran, G Mariappan, P Thakur, H Shi, JH Choi, ... Cancer research 76 (11), 3224-3235, 2016 | 158 | 2016 |
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival S Elangovan, R Pathania, S Ramachandran, S Ananth, RN Padia, L Lan, ... Cancer research 74 (4), 1166-1178, 2014 | 123 | 2014 |
SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms YD Bhutia, E Babu, S Ramachandran, S Yang, M Thangaraju, ... Biochemical Journal 473 (9), 1113-1124, 2016 | 113 | 2016 |
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate E Babu, S Ramachandran, V CoothanKandaswamy, S Elangovan, ... Oncogene 30 (38), 4026-4037, 2011 | 101 | 2011 |
Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer E Babu, YD Bhutia, S Ramachandran, JP Gnanaprakasam, PD Prasad, ... Biochemical Journal 469 (1), 17-23, 2015 | 85 | 2015 |
Cell-surface and nuclear receptors in the colon as targets for bacterial metabolites and its relevance to colon health S Sivaprakasam, YD Bhutia, S Ramachandran, V Ganapathy Nutrients 9 (8), 856, 2017 | 72 | 2017 |
Induction of growth inhibition and apoptosis in human uterine leiomyoma cells by isoliquiritigenin D Kim, S Ramachandran, S Baek, SH Kwon, KY Kwon, SD Cha, I Bae, ... Reproductive sciences 15, 552-558, 2008 | 54 | 2008 |
Growth inhibition and apoptosis induced in human leiomyoma cells by treatment with the PPAR gamma ligand ciglitizone DH Nam, S Ramachandran, DK Song, KY Kwon, DS Jeon, SJ Shin, ... Molecular Human Reproduction 13 (11), 829-836, 2007 | 41 | 2007 |
Upregulation of ATP-sensitive potassium channels for estrogen-mediated cell proliferation in human uterine leiomyoma cells SH Park, S Ramachandran, SH Kwon, SD Cha, EW Seo, I Bae, C Cho, ... Gynecological Endocrinology 24 (5), 250-256, 2008 | 36 | 2008 |
Molecular mechanism of SLC5A8 inactivation in breast cancer S Elangovan, R Pathania, S Ramachandran, S Ananth, RN Padia, ... Molecular and cellular biology 33 (19), 3920-3935, 2013 | 35 | 2013 |
Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer YD Bhutia, J Ogura, PJ Grippo, C Torres, T Sato, M Wachtel, ... Asian journal of pharmaceutical sciences 15 (2), 237-251, 2020 | 32 | 2020 |
Species-specific influence of lithium on the activity of SLC13A5 (NaCT): lithium-induced activation is specific for the transporter in primates E Gopal, E Babu, S Ramachandran, YD Bhutia, PD Prasad, V Ganapathy Journal of Pharmacology and Experimental Therapeutics 353 (1), 17-26, 2015 | 30 | 2015 |
Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3-kinase inhibition in the human cervical cancer cell-line JK Park, CH Cho, S Ramachandran, SJ Shin, SH Kwon, SY Kwon, ... Cancer research and treatment: official journal of Korean Cancer Association …, 2006 | 30 | 2006 |
RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal AE Bridges, S Ramachandran, R Pathania, U Parwal, A Lester, ... Cancer research 80 (18), 3855-3866, 2020 | 25 | 2020 |
Cyclin-dependent kinase inhibitor p27Kip1 controls growth and cell cycle progression in human uterine leiomyoma S Ramachandran, KY Kwon, SJ Shin, SH Kwon, SD Cha, I Bae, CH Cho Journal of Korean medical science 23 (4), 667, 2008 | 24 | 2008 |