Selumetinib in children with inoperable plexiform neurofibromas AM Gross, PL Wolters, E Dombi, A Baldwin, P Whitcomb, MJ Fisher, ... New England Journal of Medicine 382 (15), 1430-1442, 2020 | 526 | 2020 |
Pediatric low-grade gliomas: implications of the biologic era RJ Packer, S Pfister, E Bouffet, R Avery, P Bandopadhayay, M Bornhorst, ... Neuro-oncology 19 (6), 750-761, 2017 | 172 | 2017 |
Pediatric low-grade gliomas: next biologically driven steps DTW Jones, MW Kieran, E Bouffet, S Alexandrescu, P Bandopadhayay, ... Neuro-oncology 20 (2), 160-173, 2018 | 161 | 2018 |
Outcomes of BRAF V600E pediatric gliomas treated with targeted BRAF inhibition L Nobre, M Zapotocky, V Ramaswamy, S Ryall, J Bennett, D Alderete, ... JCO precision oncology 4, 561-571, 2020 | 115 | 2020 |
Pilocytic astrocytomas M Bornhorst, D Frappaz, RJ Packer Handbook of clinical neurology 134, 329-344, 2016 | 83 | 2016 |
Survival benefit for individuals with constitutional mismatch repair deficiency undergoing surveillance C Durno, AB Ercan, V Bianchi, M Edwards, M Aronson, M Galati, ... Journal of Clinical Oncology 39 (25), 2779-2790, 2021 | 69 | 2021 |
Management of neurofibromatosis type 1-associated plexiform neurofibromas MJ Fisher, JO Blakeley, BD Weiss, E Dombi, S Ahlawat, S Akshintala, ... Neuro-oncology 24 (11), 1827-1844, 2022 | 66 | 2022 |
A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation CY Ho, BC Mobley, H Gordish-Dressman, CJ VandenBussche, GE Mason, ... Acta neuropathologica 130, 575-585, 2015 | 62 | 2015 |
Beyond the exome: what’s next in diagnostic testing for Mendelian conditions MH Wojcik, CM Reuter, S Marwaha, M Mahmoud, MH Duyzend, ... The American Journal of Human Genetics 110 (8), 1229-1248, 2023 | 42 | 2023 |
Liquid biopsy for pediatric central nervous system tumors ER Bonner, M Bornhorst, RJ Packer, J Nazarian NPJ precision oncology 2 (1), 29, 2018 | 42 | 2018 |
The brain tumor segmentation (BRATS) challenge 2023: Focus on pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs) AF Kazerooni, N Khalili, X Liu, D Haldar, Z Jiang, SM Anwar, J Albrecht, ... arXiv preprint arXiv:2305.17033, 2023 | 38 | 2023 |
Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1 E Kim, Y Wang, SJ Kim, M Bornhorst, ES Jecrois, TE Anthony, C Wang, ... Elife 3, e05151, 2014 | 33 | 2014 |
Long-term safety and efficacy of selumetinib in children with neurofibromatosis type 1 on a phase 1/2 trial for inoperable plexiform neurofibromas AM Gross, E Dombi, PL Wolters, A Baldwin, A Dufek, K Herrera, S Martin, ... Neuro-oncology 25 (10), 1883-1894, 2023 | 30 | 2023 |
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ... Science translational medicine 13 (614), eabc0497, 2021 | 30 | 2021 |
Selumetinib in children with neurofibromatosis type 1 and asymptomatic inoperable plexiform neurofibroma at risk for developing tumor-related morbidity AM Gross, B Glassberg, PL Wolters, E Dombi, A Baldwin, MJ Fisher, ... Neuro-oncology 24 (11), 1978-1988, 2022 | 26 | 2022 |
Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors ES Jecrois, W Zheng, M Bornhorst, Y Li, DM Treisman, D Muguyo, ... Developmental Cell 56 (20), 2871-2885. e6, 2021 | 22 | 2021 |
LGG-44. A phase I dose escalation trial of the MEK1/2 inhibitor MEK162 (binimetinib) in children with low-grade gliomas and other Ras/Raf pathway-activated tumors N Robison, J Pauly, J Malvar, M Gruber-Filbin, RL de Mola, K Dorris, ... Neuro-oncology 20 (suppl_2), i114-i114, 2018 | 19 | 2018 |
Risk factors for treatment-refractory and relapsed optic pathway glioma in children with neurofibromatosis type 1 C Kotch, R Avery, KD Getz, E Bouffet, P De Blank, R Listernick, ... Neuro-oncology 24 (8), 1377-1386, 2022 | 18 | 2022 |
Blood-brain barrier–adapted precision medicine therapy for pediatric brain tumors BL Marini, LL Benitez, AH Zureick, R Salloum, AC Gauthier, J Brown, ... Translational Research 188, 27. e1-27. e14, 2017 | 16 | 2017 |
Alexander disease: a leukodystrophy that may mimic brain tumor A Tavasoli, T Armangue, CY Ho, M Whitehead, M Bornhorst, J Rhee, ... Journal of child neurology 32 (2), 184-187, 2017 | 14 | 2017 |