| Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies S Mitragotri, PA Burke, R Langer Nature reviews Drug discovery 13 (9), 655-672, 2014 | 1663 | 2014 |
| Improving protein therapeutics with sustained-release formulations SD Putney, PA Burke Nature biotechnology 16 (2), 153-157, 1998 | 656 | 1998 |
| Methods for fabricating polymer-based controlled release devices MA Tracy, JD Herberger, PA Burke, PF Herbert US Patent 5,989,463, 1999 | 400 | 1999 |
| Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment MT Abrams, ML Koser, J Seitzer, SC Williams, MA DiPietro, W Wang, ... Molecular therapy 18 (1), 171-180, 2010 | 212 | 2010 |
| Method for fabricating polymer-based controlled-release devices PA Burke US Patent 5,817,343, 1998 | 192 | 1998 |
| A potential approach for decreasing the burst effect of protein from PLGA microspheres K Fu, R Harrell, K Zinski, C Um, A Jaklenec, J Frazier, N Lotan, P Burke, ... Journal of pharmaceutical sciences 92 (8), 1582-1591, 2003 | 168 | 2003 |
| Composition for sustained release of non-aggregated erythropoietin SE Zale, PA Burke, H Bernstein, A Brickner US Patent 5,716,644, 1998 | 155 | 1998 |
| Composition for sustained release of non-aggregated erythropoietin SE Zale, PA Burke, H Bernstein, A Brickner US Patent 5,674,534, 1997 | 148 | 1997 |
| Microencapsulation and sustained release of oligonucleotides PA Burke US Patent 6,265,389, 2001 | 134 | 2001 |
| Solid-state NMR assessment of enzyme active center structure under nonaqueous conditions. PA Burke, RG Griffin, AM Klibanov Journal of Biological Chemistry 267 (28), 20057-20064, 1992 | 117 | 1992 |
| Quantitative evaluation of siRNA delivery in vivo Y Pei, PJ Hancock, H Zhang, R Bartz, C Cherrin, N Innocent, ... Rna 16 (12), 2553-2563, 2010 | 94 | 2010 |
| Protein powders for encapsulation: a comparison of spray-freeze drying and spray drying of darbepoetin alfa XC Nguyen, JD Herberger, PA Burke Pharmaceutical Research 21, 507-514, 2004 | 92 | 2004 |
| Analysis of lipid nanoparticles by Cryo-EM for characterizing siRNA delivery vehicles R Crawford, B Dogdas, E Keough, RM Haas, W Wepukhulu, S Krotzer, ... International journal of pharmaceutics 403 (1-2), 237-244, 2011 | 87 | 2011 |
| Solid‐state nuclear magnetic resonance investigation of solvent dependence of tyrosyl ring motion in an enzyme PA Burke, RG Griffin, AM Klibanov Biotechnology and bioengineering 42 (1), 87-94, 1993 | 81 | 1993 |
| Method for fabricating polymer-based controlled-release devices PA Burke US Patent 6,183,781, 2001 | 75 | 2001 |
| Demonstration of structural integrity of an enzyme in organic solvents by solid-state NMR PA Burke, SO Smith, WW Bachovchin, AM Klibanov Journal of the American Chemical Society 111 (21), 8290-8291, 1989 | 75 | 1989 |
| Poly (lactide-co-glycolide) microsphere formulations of darbepoetin alfa: spray drying is an alternative to encapsulation by spray-freeze drying PA Burke, LA Klumb, JD Herberger, XC Nguyen, RA Harrell, M Zordich Pharmaceutical research 21, 500-506, 2004 | 73 | 2004 |
| Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses W Tao, X Mao, JP Davide, B Ng, M Cai, PA Burke, AB Sachs, ... Molecular Therapy 19 (3), 567-575, 2011 | 72 | 2011 |
| Determination of internal pH in PLGA microspheres using 31P NMR spectroscopy PA Burke Proc Int Symp Control Release Bioact Mater 23 (133), e134, 1996 | 51 | 1996 |
| Advancing polymeric delivery systems amidst a nucleic acid therapy renaissance PA Burke, SH Pun, TM Reineke ACS macro letters 2 (10), 928-934, 2013 | 41 | 2013 |
