Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds M Vertzoni, J Dressman, J Butler, J Hempenstall, C Reppas European Journal of Pharmaceutics and Biopharmaceutics 60 (3), 413-417, 2005 | 464 | 2005 |
In vitro models for the prediction of in vivo performance of oral dosage forms ES Kostewicz, B Abrahamsson, M Brewster, J Brouwers, J Butler, ... European Journal of Pharmaceutical Sciences 57, 342-366, 2014 | 407 | 2014 |
The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group M Koziolek, S Alcaro, P Augustijns, AW Basit, M Grimm, B Hens, CL Hoad, ... European Journal of Pharmaceutical Sciences 134, 31-59, 2019 | 311 | 2019 |
Estimating drug solubility in the gastrointestinal tract JB Dressman, M Vertzoni, K Goumas, C Reppas Advanced drug delivery reviews 59 (7), 591-602, 2007 | 284 | 2007 |
Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects M Vertzoni, N Fotaki, E Nicolaides, C Reppas, E Kostewicz, E Stippler, ... Journal of pharmacy and pharmacology 56 (4), 453-462, 2004 | 284 | 2004 |
Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults D Psachoulias, M Vertzoni, K Goumas, V Kalioras, S Beato, J Butler, ... Pharmaceutical research 28, 3145-3158, 2011 | 226 | 2011 |
In-vitro simulation of luminal conditions for evaluation of performance of oral drug products: Choosing the appropriate test media C Markopoulos, CJ Andreas, M Vertzoni, J Dressman, C Reppas European Journal of Pharmaceutics and Biopharmaceutics 93, 173-182, 2015 | 204 | 2015 |
Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review M Vertzoni, P Augustijns, M Grimm, M Koziolek, G Lemmens, N Parrott, ... European journal of pharmaceutical sciences 134, 153-175, 2019 | 203 | 2019 |
Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review Z Vinarov, M Abdallah, JAG Agundez, K Allegaert, AW Basit, ... European Journal of Pharmaceutical Sciences 162, 105812, 2021 | 200 | 2021 |
Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling Y Shono, E Jantratid, N Janssen, F Kesisoglou, Y Mao, M Vertzoni, ... European Journal of Pharmaceutics and Biopharmaceutics 73 (1), 107-114, 2009 | 181 | 2009 |
Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form E Jantratid, V De Maio, E Ronda, V Mattavelli, M Vertzoni, JB Dressman European Journal of Pharmaceutical Sciences 37 (3-4), 434-441, 2009 | 181 | 2009 |
Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults A Diakidou, M Vertzoni, K Goumas, E Söderlind, B Abrahamsson, ... Pharmaceutical research 26, 2141-2151, 2009 | 150 | 2009 |
Biorelevant dissolution methods and their applications in in vitro-in vivo correlations for oral formulations N Fotaki, M Vertzoni The Open Drug Delivery Journal 4 (1), 2010 | 142 | 2010 |
Biorelevant media to simulate fluids in the ascending colon of humans and their usefulness in predicting intracolonic drug solubility M Vertzoni, A Diakidou, M Chatzilias, E Söderlind, B Abrahamsson, ... Pharmaceutical research 27, 2187-2196, 2010 | 138 | 2010 |
Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate BT Griffin, M Kuentz, M Vertzoni, ES Kostewicz, Y Fei, W Faisal, C Stillhart, ... European Journal of Pharmaceutics and Biopharmaceutics 86 (3), 427-437, 2014 | 137 | 2014 |
Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles D Juenemann, E Jantratid, C Wagner, C Reppas, M Vertzoni, ... European journal of pharmaceutics and biopharmaceutics 77 (2), 257-264, 2011 | 127 | 2011 |
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration J Butler, B Hens, M Vertzoni, J Brouwers, P Berben, J Dressman, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 70-83, 2019 | 122 | 2019 |
Estimation of intragastric solubility of drugs: in what medium? M Vertzoni, E Pastelli, D Psachoulias, L Kalantzi, C Reppas Pharmaceutical research 24, 909-917, 2007 | 113 | 2007 |
Drug supersaturation in simulated human intestinal fluids representing different nutritional states J Bevernage, J Brouwers, S Clarysse, M Vertzoni, JAN Tack, P Annaert, ... Journal of pharmaceutical sciences 99 (11), 4525-4534, 2010 | 112 | 2010 |
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network Z Vinarov, B Abrahamsson, P Artursson, H Batchelor, P Berben, ... Advanced Drug Delivery Reviews 171, 289-331, 2021 | 102 | 2021 |