Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development H Yu, O Alkhamis, J Canoura, Y Liu, Y Xiao Angewandte Chemie International Edition 60 (31), 16800-16823, 2021 | 263 | 2021 |
Innovative engineering and sensing strategies for aptamer-based small-molecule detection O Alkhamis, J Canoura, H Yu, Y Liu, Y Xiao TrAC Trends in Analytical Chemistry 121, 115699, 2019 | 123 | 2019 |
Immobilization strategies for enhancing sensitivity of electrochemical aptamer-based sensors Y Liu, J Canoura, O Alkhamis, Y Xiao ACS applied materials & interfaces 13 (8), 9491-9499, 2021 | 75 | 2021 |
No structure-switching required: a generalizable exonuclease-mediated aptamer-based assay for small-molecule detection J Canoura, Z Wang, H Yu, O Alkhamis, F Fu, Y Xiao Journal of the American Chemical Society 140 (31), 9961-9971, 2018 | 73 | 2018 |
Accelerating post-SELEX aptamer engineering using exonuclease digestion J Canoura, H Yu, O Alkhamis, D Roncancio, R Farhana, Y Xiao Journal of the American Chemical Society 143 (2), 805-816, 2020 | 64 | 2020 |
Label-free, visual detection of small molecules using highly target-responsive multimodule split aptamer constructs Y Luo, H Yu, O Alkhamis, Y Liu, X Lou, B Yu, Y Xiao Analytical chemistry 91 (11), 7199-7207, 2019 | 64 | 2019 |
Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation Z Wang, H Yu, J Canoura, Y Liu, O Alkhamis, F Fu, Y Xiao Nucleic acids research 46 (13), e81-e81, 2018 | 62 | 2018 |
Fabrication of Aptamer‐modified paper electrochemical devices for on‐site biosensing H Yu, Z Chen, Y Liu, O Alkhamis, Z Song, Y Xiao Angewandte Chemie 133 (6), 3030-3037, 2021 | 55 | 2021 |
In vitro isolation of class-specific oligonucleotide-based small-molecule receptors W Yang, H Yu, O Alkhamis, Y Liu, J Canoura, F Fu, Y Xiao Nucleic acids research 47 (12), e71-e71, 2019 | 54 | 2019 |
In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality H Yu, W Yang, O Alkhamis, J Canoura, KA Yang, Y Xiao Nucleic Acids Research 46 (8), e43-e43, 2018 | 47 | 2018 |
Isolation of natural DNA aptamers for challenging small-molecule targets, cannabinoids H Yu, Y Luo, O Alkhamis, J Canoura, B Yu, Y Xiao Analytical chemistry 93 (6), 3172-3180, 2021 | 46 | 2021 |
Sensitive detection of small-molecule targets using cooperative binding split aptamers and enzyme-assisted target recycling H Yu, J Canoura, B Guntupalli, O Alkhamis, Y Xiao Analytical chemistry 90 (3), 1748-1758, 2018 | 37 | 2018 |
DNA Aptamer–Cyanine Complexes as Generic Colorimetric Small‐Molecule Sensors O Alkhamis, J Canoura, KV Bukhryakov, A Tarifa, AP DeCaprio, Y Xiao Angewandte Chemie 134 (3), e202112305, 2022 | 30 | 2022 |
Tuning biosensor cross-reactivity using aptamer mixtures Y Liu, H Yu, O Alkhamis, J Moliver, Y Xiao Analytical chemistry 92 (7), 5041-5047, 2020 | 30 | 2020 |
Dithiothreitol-regulated coverage of oligonucleotide-modified gold nanoparticles to achieve optimized biosensor performance P Liang, J Canoura, H Yu, O Alkhamis, Y Xiao ACS applied materials & interfaces 10 (4), 4233-4242, 2018 | 27 | 2018 |
Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease O Alkhamis, W Yang, R Farhana, H Yu, Y Xiao Nucleic Acids Research 48 (20), e120-e120, 2020 | 26 | 2020 |
Systematic Study of in Vitro Selection Stringency Reveals How To Enrich High-Affinity Aptamers O Alkhamis, Y Xiao Journal of the American Chemical Society 145 (1), 194-206, 2022 | 21 | 2022 |
Aptamer-integrated multianalyte-detecting paper electrochemical device Y Liu, O Alkhamis, X Liu, H Yu, J Canoura, Y Xiao ACS applied materials & interfaces 13 (15), 17330-17339, 2021 | 19 | 2021 |
Using exonucleases for aptamer characterization, engineering, and sensing O Alkhamis, J Canoura, PT Ly, Y Xiao Accounts of Chemical Research 56 (13), 1731-1743, 2023 | 11 | 2023 |
Comparison of aptamer signaling mechanisms reveals disparities in sensor response and strategies to eliminate false signals O Alkhamis, J Canoura, C Willis, L Wang, J Perry, Y Xiao Journal of the American Chemical Society 145 (22), 12407-12422, 2023 | 11 | 2023 |