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Integrated genomic and molecular characterization of cervical cancer TCGAR Network Nature 543, 378-384, 2017 | 1127* | 2017 |
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An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers K Chan, SA Roberts, LJ Klimczak, JF Sterling, N Saini, EP Malc, J Kim, ... Nature genetics 47 (9), 1067, 2015 | 423 | 2015 |
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Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome BJ Trask, H Massa, V Brand-Arpon, K Chan, C Friedman, OT Nguyen, ... Human molecular genetics 7 (13), 2007-2020, 1998 | 136 | 1998 |
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Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent K Chan, JF Sterling, SA Roberts, AS Bhagwat, MA Resnick, DA Gordenin PLoS genetics 8 (12), e1003149, 2012 | 112 | 2012 |
The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts N Saini, SA Roberts, LJ Klimczak, K Chan, SA Grimm, S Dai, DC Fargo, ... PLoS genetics 12 (10), e1006385, 2016 | 103 | 2016 |
The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis K Chan, MA Resnick, DA Gordenin DNA repair 12 (11), 878-889, 2013 | 96 | 2013 |
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Multiple specific binding targets for inhaled anesthetics in the mammalian brain MF Eckenhoff, K Chan, RG Eckenhoff Journal of Pharmacology and Experimental Therapeutics 300 (1), 172-179, 2002 | 46 | 2002 |
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 1-27, 2020 | 41 | 2020 |
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation CJ Sakofsky, N Saini, LJ Klimczak, K Chan, EP Malc, PA Mieczkowski, ... PLoS Biology 17 (9), e3000464, 2019 | 40 | 2019 |
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes SM Waszak, G Tiao, B Zhu, T Rausch, F Muyas, B Rodriguez-Martin, ... bioRxiv, 2017 | 34 | 2017 |
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Suspended animation extends survival limits of Caenorhabditis elegans and Saccharomyces cerevisiae at low temperature K Chan, JP Goldmark, MB Roth Molecular biology of the cell 21 (13), 2161-2171, 2010 | 13 | 2010 |