Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors JL Shepherdson, RZ Friedman, Y Zheng, C Sun, IY Oh, DM Granas, ... Genome Research 34 (2), 243-255, 2024 | 10 | 2024 |
Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation J Wang, X Cheng, Q Liang, LA Owen, J Lu, Y Zheng, M Wang, S Chen, ... Genome biology 24 (1), 269, 2023 | 9 | 2023 |
Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms Y Zheng, C Sun, X Zhang, PA Ruzycki, S Chen Elife 12, RP87147, 2023 | 9 | 2023 |
Integrated multi-omics single cell atlas of the human retina J Li, J Wang, IL Ibarra, X Cheng, MD Luecken, J Lu, A Monavarfeshani, ... Research Square, 2023 | 9 | 2023 |
Transcriptional precision in photoreceptor development and diseases–Lessons from 25 years of CRX research Y Zheng, S Chen Frontiers in cellular neuroscience 18, 1347436, 2024 | 3 | 2024 |
Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models Y Zheng, GD Stormo, S Chen bioRxiv, 2024 | | 2024 |
Deciphering how missense mutations in CRX homeodomain produce distinct dominant retinopathies Y Zheng, C Sun, X Zhang, PA Ruzycki, S Chen Investigative Ophthalmology & Visual Science 63 (7), 3817-3817, 2022 | | 2022 |