Iron overload inhibits late stage autophagic flux leading to insulin resistance JWS Jahng, RM Alsaadi, R Palanivel, E Song, VEB Hipolito, HK Sung, ... EMBO reports 20 (10), e47911, 2019 | 87 | 2019 |
Lipocalin‐2 (NGAL) attenuates autophagy to exacerbate cardiac apoptosis induced by myocardial ischemia HK Sung, YK Chan, M Han, JWS Jahng, E Song, E Danielson, T Berger, ... Journal of Cellular Physiology 232 (8), 2125-2134, 2017 | 73 | 2017 |
Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress HK Sung, E Song, JWS Jahng, K Pantopoulos, G Sweeney Scientific reports 9 (1), 4668, 2019 | 70 | 2019 |
Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells YK Chan, HK Sung, JWS Jahng, GHE Kim, M Han, G Sweeney Molecular and cellular endocrinology 430, 68-76, 2016 | 60 | 2016 |
Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge E Song, JWS Jahng, LP Chong, HK Sung, M Han, C Luo, D Wu, S Boo, ... American journal of translational research 9 (6), 2723, 2017 | 50 | 2017 |
Holo-lipocalin-2–derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes E Song, SV Ramos, X Huang, Y Liu, A Botta, HK Sung, PC Turnbull, ... Proceedings of the National Academy of Sciences 115 (7), 1576-1581, 2018 | 44 | 2018 |
ALY688 elicits adiponectin-mimetic signaling and improves insulin action in skeletal muscle cells HK Sung, PL Mitchell, S Gross, A Marette, G Sweeney American Journal of Physiology-Cell Physiology 322 (2), C151-C163, 2022 | 26 | 2022 |
Iron metabolism and regulation by neutrophil gelatinase-associated lipocalin in cardiomyopathy YK Chan, HK Sung, G Sweeney Clinical Science 129 (10), 851-862, 2015 | 26 | 2015 |
Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells HK Sung, M Murugathasan, AA Abdul-Sater, G Sweeney Cell Death & Disease 14 (4), 252, 2023 | 20 | 2023 |
Effects of the adiponectin mimetic compound ALY688 on glucose and fat metabolism in visceral and subcutaneous rat adipocytes D Da Eira, S Jani, H Sung, G Sweeney, RB Ceddia Adipocyte 9 (1), 550-562, 2020 | 17 | 2020 |
Role of mitochondrial iron overload in mediating cell death in H9c2 cells E Tam, HK Sung, NH Lam, S You, S Cho, SM Ahmed, AA Abdul-Sater, ... Cells 12 (1), 118, 2022 | 15 | 2022 |
MitoNEET prevents iron overload‐induced insulin resistance in H9c2 cells through regulation of mitochondrial iron E Tam, HK Sung, G Sweeney Journal of Cellular Physiology 238 (8), 1867-1875, 2023 | 10 | 2023 |
Iron overload reduces adiponectin receptor expression via a ROS/FOXO1‐dependent mechanism leading to adiponectin resistance in skeletal muscle cells K Dahyaleh, HK Sung, M Prioriello, P Rengasamy, NH Lam, JB Kim, ... Journal of Cellular Physiology 236 (7), 5339-5351, 2021 | 10 | 2021 |
Inhibitory effects of terrein on lung cancer cell metastasis and angiogenesis P Buachan, M Namsa-Aid, HK Sung, C Peng, G Sweeney, ... Oncology Reports 45 (6), 94, 2021 | 9 | 2021 |
Genotoxic effect of air-borne particulate matter in residential area of Seoul City OS Min, SH Kyoung, KE Sil, RB Taek, CK Hyuck Environmental Analysis Health and Toxicology 20 (4), 365-374, 2005 | 6 | 2005 |
Cardioprotection by the adiponectin receptor agonist ALY688 in a preclinical mouse model of heart failure with reduced ejection fraction (HFrEF) S Cho, K Dadson, HK Sung, O Ayansola, A Mirzaesmaeili, N Noskovicova, ... Biomedicine & Pharmacotherapy 171, 116119, 2024 | 5 | 2024 |
Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress. Sci Rep. 2019; 9: 4668 HK Sung, E Song, JWS Jahng, K Pantopoulos, G Sweeney | 5 | |
Salubrinal promotes phospho-eIF2α-dependent activation of UPR leading to autophagy-mediated attenuation of iron-induced insulin resistance K Nguyen, J Tang, S Cho, F Ying, HK Sung, JW Jahng, K Pantopoulos, ... Molecular Metabolism 83, 101921, 2024 | 4 | 2024 |
Use of 2-dimensional cell monolayers and 3-dimensional microvascular networks on microfluidic devices shows that iron increases transendothelial adiponectin flux via inducing … N Yoon, S Kim, HK Sung, TQ Dang, JS Jeon, G Sweeney Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (2), 129796, 2021 | 3 | 2021 |
Regulation of Iron and Its Significance in Obesity and Complications. YK Chan, HK Sung, G Sweeney Korean Journal of Obesity 23 (4), 2014 | 3 | 2014 |