Obesity-induced CerS6-dependent C16: 0 ceramide production promotes weight gain and glucose intolerance SM Turpin, HT Nicholls, DM Willmes, A Mourier, S Brodesser, ... Cell metabolism 20 (4), 678-686, 2014 | 630 | 2014 |
Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding MC Vogt, L Paeger, S Hess, SM Steculorum, M Awazawa, B Hampel, ... Cell 156 (3), 495-509, 2014 | 372 | 2014 |
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b JW Kornfeld, C Baitzel, AC Könner, HT Nicholls, MC Vogt, K Herrmanns, ... Nature 494 (7435), 111-115, 2013 | 354 | 2013 |
CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity P Hammerschmidt, D Ostkotte, H Nolte, MJ Gerl, A Jais, HL Brunner, ... Cell 177 (6), 1536-1552. e23, 2019 | 214 | 2019 |
Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss J Schmitz, N Evers, M Awazawa, HT Nicholls, HS Brönneke, A Dietrich, ... Molecular metabolism 5 (5), 328-339, 2016 | 129 | 2016 |
Hematopoietic cell–restricted deletion of CD36 reduces high-fat diet–induced macrophage infiltration and improves insulin signaling in adipose tissue HT Nicholls, G Kowalski, DJ Kennedy, S Risis, LA Zaffino, N Watson, ... Diabetes 60 (4), 1100-1110, 2011 | 82 | 2011 |
Dissociation of adaptive thermogenesis from glucose homeostasis in microbiome-deficient mice TI Krisko, HT Nicholls, CJ Bare, CD Holman, GG Putzel, RS Jansen, ... Cell Metabolism 31 (3), 592-604. e9, 2020 | 67 | 2020 |
Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice GM Kowalski, HT Nicholls, S Risis, NK Watson, P Kanellakis, CR Bruce, ... Diabetologia 54, 888-899, 2011 | 65 | 2011 |
Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis HT Nicholls, JL Hornick, DE Cohen American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (1 …, 2017 | 12 | 2017 |
IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade GI Lancaster, B Skiba, C Yang, HT Nicholls, KG Langley, MHS Chan, ... Biochemical Journal 442 (3), 723-732, 2012 | 7 | 2012 |
Up‐regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice N Imai, HT Nicholls, M Alves‐Bezerra, Y Li, AA Ivanova, EA Ortlund, ... Hepatology 75 (1), 154-169, 2022 | 6 | 2022 |
Regulation of adaptive thermogenesis by the gut microbiome HT Nicholls, TI Krisko, KB LeClair, AS Banks, DE Cohen The FASEB Journal 30, 854.2-854.2, 2016 | 6 | 2016 |
Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy S Tholen, R Patel, A Agas, KM Kovary, A Rabiee, HT Nicholls, ... Cell reports 39 (13), 2022 | 5 | 2022 |
Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice Y Li, N Imai, HT Nicholls, BR Roberts, S Goyal, TI Krisko, LH Ang, ... Nature Communications 12 (1), 3493, 2021 | 1 | 2021 |
Thioesterase superfamily member 1 undergoes stimulus-coupled reorganization to regulate metabolism Y Li, N Imai, S Goyal, HT Nicholls, TI Krisko, M Baqai, LH Ang, MC Tillman, ... bioRxiv, 2020.02. 18.954818, 2020 | 1 | 2020 |
Hepatology Highlights N Imai, TI Krisko, ZH Tafesh, C Lucero, M Alves‐Bezerra, HT Nicholls, ... Hepatology 68 (5), 1665-1667, 2018 | 1 | 2018 |
Phosphatidylcholine Transfer Protein (PC‐TP) Regulates Lipid Droplet Morphology in Experimental Non‐Alcoholic Steatohepatitis (NASH) HT Nicholls, J Song, J Wu, JL Hornick, DE Cohen The FASEB Journal 30, 1128.1-1128.1, 2016 | 1 | 2016 |
Regulation of Adaptive Thermogenesis by the Gut Microbiome: Implications for Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis TI Krisko, HT Nicholls, KB Leclair, AS Banks, DE Cohen Hepatology 62, 645A-645A, 2015 | 1 | 2015 |
Suppression of Fatty Acid Oxidation by Thioesterase Superfamily Member 2 in Skeletal Muscle Promotes Hepatic Steatosis and Insulin Resistance N Imai, HT Nicholls, M Alves-Bezerra, Y Li, AA Ivanova, EA Ortlund, ... bioRxiv, 2021.04. 21.440732, 2021 | | 2021 |
Su1597 PORTAL VEIN METABOLITE PROFILING REVEALS MICROBIOME-DEPENDENT METABOLIC CONTROL OF HEPATIC GLUCONEOGENESIS: IMPLICATIONS FOR OBESITY-RELATED METABOLIC DISORDERS T Krisko, HT Nicholls, AS Banks, D Cohen Gastroenterology 158 (6), S-1352, 2020 | | 2020 |