Cancer stem cells: an evolving concept LV Nguyen, R Vanner, P Dirks, CJ Eaves Nature Reviews Cancer 12 (2), 133-143, 2012 | 1371 | 2012 |
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015 | 659 | 2015 |
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ... Nature 549 (7671), 227-232, 2017 | 433 | 2017 |
Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells LV Nguyen, D Pellacani, S Lefort, N Kannan, T Osako, M Makarem, ... Nature 528 (7581), 267-271, 2015 | 125 | 2015 |
Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice AMS Cheung, LV Nguyen, A Carles, P Beer, PH Miller, DJHF Knapp, ... Blood, The Journal of the American Society of Hematology 122 (18), 3129-3137, 2013 | 124 | 2013 |
DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts LV Nguyen, CL Cox, P Eirew, DJHF Knapp, D Pellacani, N Kannan, ... Nature communications 5 (1), 1-9, 2014 | 113 | 2014 |
Glutathione-dependent and-independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets N Kannan, LV Nguyen, M Makarem, Y Dong, K Shih, P Eirew, A Raouf, ... Proceedings of the National Academy of Sciences 111 (21), 7789-7794, 2014 | 93 | 2014 |
Molecular determinants of PAM2 recognition by the MLLE domain of poly (A)-binding protein G Kozlov, M Ménade, A Rosenauer, L Nguyen, K Gehring Journal of molecular biology 397 (2), 397-407, 2010 | 91 | 2010 |
Modeling the process of human tumorigenesis S Balani, LV Nguyen, CJ Eaves Nature communications 8 (1), 1-10, 2017 | 84 | 2017 |
Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD G Kozlov, L Nguyen, T Lin, G De Crescenzo, M Park, K Gehring Journal of Biological Chemistry 282 (49), 35787-35795, 2007 | 83 | 2007 |
Clonal analysis via barcoding reveals diverse growth and differentiation of transplanted mouse and human mammary stem cells LV Nguyen, M Makarem, A Carles, M Moksa, N Kannan, P Pandoh, ... Cell Stem Cell 14 (2), 253-263, 2014 | 80 | 2014 |
Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells M Makarem, N Kannan, LV Nguyen, DJHF Knapp, S Balani, MD Prater, ... PLoS biology 11 (8), e1001630, 2013 | 75 | 2013 |
Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases N Wang, L Fallavollita, L Nguyen, J Burnier, M Rafei, J Galipeau, S Yakar, ... Molecular Therapy 17 (7), 1241-1249, 2009 | 36 | 2009 |
Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer LV Nguyen, K Searle, KJ Jerzak Oncotarget 10 (59), 6317, 2019 | 32 | 2019 |
Integrin β3 links therapy resistance and cancer stem cell properties N Kannan, LV Nguyen, CJ Eaves Nature cell biology 16 (5), 397-399, 2014 | 29 | 2014 |
Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding L Nguyen, G Kozlov, K Gehring FEBS letters 582 (5), 623-626, 2008 | 13 | 2008 |
The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid G Kozlov, L Nguyen, J Pearsall, K Gehring Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 10 | 2009 |
Functional genomics approaches to improve pre‐clinical drug screening and biomarker discovery LV Nguyen, C Caldas EMBO Molecular Medicine 13 (9), e13189, 2021 | 7 | 2021 |
Scientific overview: CSCI-CITAC annual general meeting and young investigator’s forum 2010 M Berger, D Bosse, MS Kuruvilla, P Lang, JC Murray, LV Nguyen Clinical and Investigative Medicine, E105-E110, 2011 | 2 | 2011 |
Abstract A63: Clonal analysis of normal and malignant human mammary epithelial cell responsiveness to radiation S Balani, N Kannan, LV Nguyen, S Lefort, D Pellacani, CJ Eaves Molecular Cancer Research 14 (2 Supplement), A63-A63, 2016 | 1 | 2016 |