A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing WW Zhang, S Karmakar, S Gannavaram, R Dey, P Lypaczewski, N Ismail, ... Nature Communications 11 (1), 3461, 2020 | 100 | 2020 |
Mechanisms of immunopathogenesis in cutaneous leishmaniasis and post kala-azar dermal leishmaniasis (PKDL) G Volpedo, T Pacheco-Fernandez, EA Holcomb, N Cipriano, B Cox, ... Frontiers in cellular and infection microbiology 11, 685296, 2021 | 72 | 2021 |
STAT1 inhibits T‐cell exhaustion and myeloid derived suppressor cell accumulation to promote antitumor immune responses in head and neck squamous cell carcinoma N Ryan, K Anderson, G Volpedo, O Hamza, S Varikuti, AR Satoskar, ... International journal of cancer 146 (6), 1717-1729, 2020 | 66 | 2020 |
Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells S Varikuti, B Singh, G Volpedo, DK Ahirwar, BK Jha, N Saljoughian, ... British Journal of Cancer 122 (7), 1005-1013, 2020 | 65 | 2020 |
Host-directed drug therapies for neglected tropical diseases caused by protozoan parasites S Varikuti, BK Jha, G Volpedo, NM Ryan, G Halsey, OM Hamza, ... Frontiers in microbiology 9, 2655, 2018 | 61 | 2018 |
Cutting edge: CXCR3 escapes X chromosome inactivation in T cells during infection: potential implications for sex differences in immune responses S Oghumu, S Varikuti, JC Stock, G Volpedo, N Saljoughian, CA Terrazas, ... The Journal of Immunology 203 (4), 789-794, 2019 | 53 | 2019 |
Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases G Volpedo, L Costa, N Ryan, G Halsey, A Satoskar, S Oghumu Journal of Venomous Animals and Toxins including Tropical Diseases 25, e144118, 2019 | 46 | 2019 |
From infection to vaccination: reviewing the global burden, history of vaccine development, and recurring challenges in global leishmaniasis protection G Volpedo, RH Huston, EA Holcomb, T Pacheco-Fernandez, ... Expert review of vaccines 20 (11), 1431-1446, 2021 | 45 | 2021 |
Revival of leishmanization and leishmanin T Pacheco-Fernandez, G Volpedo, S Gannavaram, P Bhattacharya, ... Frontiers in Cellular and Infection Microbiology 11, 639801, 2021 | 40 | 2021 |
STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade S Varikuti, S Oghumu, M Elbaz, G Volpedo, DK Ahirwar, PC Alarcon, ... Oncoimmunology 6 (11), e1361088, 2017 | 40 | 2017 |
Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis S Karmakar, N Ismail, F Oliveira, J Oristian, WW Zhang, S Kaviraj, ... Communications biology 4 (1), 929, 2021 | 35 | 2021 |
Determinants of innate immunity in visceral leishmaniasis and their implication in vaccine development G Volpedo, T Pacheco-Fernandez, P Bhattacharya, T Oljuskin, R Dey, ... Frontiers in immunology 12, 748325, 2021 | 34 | 2021 |
Immune suppression mediated by STAT4 deficiency promotes lymphatic metastasis in HNSCC K Anderson, N Ryan, G Volpedo, S Varikuti, AR Satoskar, S Oghumu Frontiers in immunology 10, 3095, 2020 | 25 | 2020 |
The Potent ITK/BTK Inhibitor Ibrutinib Is Effective for the Treatment of Experimental Visceral Leishmaniasis Caused by Leishmania donovani S Varikuti, G Volpedo, N Saljoughian, OM Hamza, G Halsey, NM Ryan, ... The Journal of infectious diseases 219 (4), 599-608, 2019 | 25 | 2019 |
Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis G Volpedo, T Pacheco-Fernandez, EA Holcomb, WW Zhang, ... NPJ vaccines 7 (1), 32, 2022 | 24 | 2022 |
Host-directed therapies for parasitic diseases B Singh, S Varikuti, G Halsey, G Volpedo, OM Hamza, AR Satoskar Future medicinal chemistry 11 (16), 1999-2018, 2019 | 23 | 2019 |
The History of Live Attenuated Centrin Gene-Deleted Leishmania Vaccine Candidates G Volpedo, P Bhattacharya, S Gannavaram, T Pacheco-Fernandez, ... Pathogens 11 (4), 431, 2022 | 22 | 2022 |
MicroRNA-155 deficiency exacerbates Trypanosoma cruzi infection BK Jha, S Varikuti, GR Seidler, G Volpedo, AR Satoskar, BS McGwire Infection and immunity 88 (7), 10.1128/iai. 00948-19, 2020 | 22 | 2020 |
The IL-33/ST2 axis in immune responses against parasitic disease: potential therapeutic applications N Ryan, K Anderson, G Volpedo, S Varikuti, M Satoskar, S Satoskar, ... Frontiers in cellular and infection microbiology 10, 153, 2020 | 21 | 2020 |
MicroRNA 155 contributes to host immunity against Leishmania donovani but is not essential for resolution of infection S Varikuti, G Natarajan, G Volpedo, B Singh, O Hamza, GV Messick, ... Infection and Immunity 87 (8), 10.1128/iai. 00307-19, 2019 | 18 | 2019 |