| Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction J Sohn, J Rudolph Biochemistry 42 (34), 10060-10070, 2003 | 213 | 2003 |
| Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death H Jiang, X Xue, S Panda, A Kawale, RM Hooy, F Liang, J Sohn, P Sung, ... The EMBO journal 38 (21), e102718, 2019 | 209 | 2019 |
| Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy SR Morrone, T Wang, LM Constantoulakis, RM Hooy, MJ Delannoy, ... Proceedings of the National Academy of Sciences 111 (1), E62-E71, 2014 | 198 | 2014 |
| Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC SR Morrone, M Matyszewski, X Yu, M Delannoy, EH Egelman, J Sohn Nature communications 6 (1), 7827, 2015 | 158 | 2015 |
| Allosteric activation of DegS, a stress sensor PDZ protease J Sohn, RA Grant, RT Sauer Cell 131 (3), 572-583, 2007 | 138 | 2007 |
| Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond, G Buhrman, B Parker, J Sohn, J Rudolph, C Mattos Biochemistry 44 (14), 5307-5316, 2005 | 127 | 2005 |
| The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex SA Stratmann, SR Morrone, AM van Oijen, J Sohn Elife 4, e11721, 2015 | 97 | 2015 |
| Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones J Sohn, B Kiburz, Z Li, L Deng, A Safi, MC Pirrung, J Rudolph Journal of medicinal chemistry 46 (13), 2580-2588, 2003 | 93 | 2003 |
| Signal integration by DegS and RseB governs the σE-mediated envelope stress response in Escherichia coli R Chaba, BM Alba, MS Guo, J Sohn, N Ahuja, RT Sauer, CA Gross Proceedings of the National Academy of Sciences 108 (5), 2106-2111, 2011 | 84 | 2011 |
| Digital signaling network drives the assembly of the AIM2-ASC inflammasome M Matyszewski, SR Morrone, J Sohn Proceedings of the National Academy of Sciences 115 (9), E1963-E1972, 2018 | 64 | 2018 |
| Filament assemblies in foreign nucleic acid sensors J Sohn, S Hur Current opinion in structural biology 37, 134-144, 2016 | 64 | 2016 |
| Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS RM Hooy, G Massaccesi, KE Rousseau, MA Chattergoon, J Sohn Nucleic acids research 48 (8), 4435-4447, 2020 | 61 | 2020 |
| The allosteric activation of cGAS underpins its dynamic signaling landscape RM Hooy, J Sohn Elife 7, e39984, 2018 | 61 | 2018 |
| Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2− CycA Protein Substrate J Sohn, JM Parks, G Buhrman, P Brown, K Kristjánsdóttir, A Safi, ... Biochemistry 44 (50), 16563-16573, 2005 | 58 | 2005 |
| Remote hot spots mediate protein substrate recognition for the Cdc25 phosphatase J Sohn, K Kristjánsdóttir, A Safi, B Parker, B Kiburz, J Rudolph Proceedings of the National Academy of Sciences 101 (47), 16437-16441, 2004 | 57 | 2004 |
| OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations J Sohn, RT Sauer Molecular cell 33 (1), 64-74, 2009 | 55 | 2009 |
| Association of antibodies to interferon‐inducible protein‐16 with markers of more severe disease in primary Sjögren's syndrome AN Baer, M Petri, J Sohn, A Rosen, L Casciola‐Rosen Arthritis care & research 68 (2), 254-260, 2016 | 53 | 2016 |
| OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism J Sohn, RA Grant, RT Sauer Structure 17 (10), 1411-1421, 2009 | 53 | 2009 |
| Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution J Sohn, RA Grant, RT Sauer Journal of biological chemistry 285 (44), 34039-34047, 2010 | 37 | 2010 |
| A conserved activation cluster is required for allosteric communication in HtrA-family proteases AK De Regt, S Kim, J Sohn, RA Grant, TA Baker, RT Sauer Structure 23 (3), 517-526, 2015 | 33 | 2015 |
