New potential antitumor quinazolinones derived from dynamic 2-undecyl benzoxazinone: synthesis and cytotoxic evaluation MH Hekal, FSM Abu El-Azm Synthetic Communications 48 (18), 2391-2402, 2018 | 31 | 2018 |
Synthesis of new oxadiazol-phthalazinone derivatives with anti-proliferative activity; molecular docking, pro-apoptotic, and enzyme inhibition profile MH Hekal, AM El-Naggar, FSMA El-Azm, WM El-Sayed RSC advances 10 (7), 3675-3688, 2020 | 26 | 2020 |
Synthesis and antitumor evaluation of novel tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrimido[1,2-b]isoquinoline derivatives MR Mahmoud, FSM Abu El-Azm, MF Ismail, MH Hekal, YM Ali Synthetic Communications 48 (4), 428-438, 2018 | 22 | 2018 |
Design, synthesis, and evaluation of some novel heterocycles bearing pyrazole moiety as potential anticancer agents N Abdelgawad, MF Ismail, MH Hekal, MI Marzouk Journal of Heterocyclic Chemistry 56 (6), 1771-1779, 2019 | 21 | 2019 |
Efficient MW‐Assisted Synthesis of Some New Isoquinolinone Derivatives With In Vitro Antitumor Activity MH Hekal, FSM Abu El‐Azm Journal of Heterocyclic Chemistry 54 (6), 3056-3064, 2017 | 20 | 2017 |
Ecofriendly and highly efficient microwave-induced synthesis of novel quinazolinone-undecyl hybrids with in vitro antitumor activity MH Hekal, FSM Abu El-Azm, SR Atta-Allah Synthetic Communications 49 (20), 2630-2641, 2019 | 19 | 2019 |
New N-(1, 3, 4-thiadiazol-2-yl) furan-2-carboxamide derivatives as potential inhibitors of the VEGFR-2 MH Hekal, PS Farag, MM Hemdan, WM El-Sayed Bioorganic Chemistry 115, 105176, 2021 | 18 | 2021 |
N'-(1-([1,1'-biphenyl]-4-yl)ethylidene)-2-cyanoacetohydrazide as scaffold for the synthesis of diverse heterocyclic compounds as prospective antitumor and … NA Hamed, MI Marzouk, MF Ismail, MH Hekal Synthetic Communications 49 (21), 3017-3029, 2019 | 17 | 2019 |
Novel Synthesis of Isoquinoline Derivatives Derived from (Z)-4-(1,3-Diphenylpyrazol-4-yl)isochromene-1,3-dione MR Mahmoud, MM El-Shahawi, WSI Abou-Elmagd, MH Hekal Synthetic Communications 45 (14), 1632-1641, 2015 | 17 | 2015 |
Synthesis and spectral characterisation of some phthalazinone derivatives MR Mahmoud, WSI Abou-Elmagd, HA Derbala, MH Hekal Journal of Chemical Research 36 (2), 75-82, 2012 | 17 | 2012 |
Novel fused and spiro heterocyclic compounds derived from 4-(4-amino-5-mercapto-4h-1, 2, 4-triazol-3-yl) phthalazin-1 (2h)-one MR Mahmoud, WSI Abou-Elmagd, MM El-Shahawi, MH Hekal Eur. Chem. Bull 3 (7), 723-728, 2014 | 16 | 2014 |
Novel synthesis of some phthalazinone derivatives MR Mahmoud, WSI Abou‐Elmagd, HA Derbala, MH Hekal Chinese Journal of Chemistry 29 (7), 1446-1450, 2011 | 16 | 2011 |
Convenient synthesis and anti-proliferative activity of some benzochromenes and chromenotriazolopyrimidines under classical methods and phase transfer catalysis AT Ali, MH Hekal Synthetic Communications 49 (24), 3498-3509, 2019 | 12 | 2019 |
Synthesis, Spectral Characterization, and In Vitro Biological Evaluation of Some Novel Isoquinolinone‐based Heterocycles as Potential Antitumor Agents MH Hekal, FSM Abu El‐Azm, HA Sallam Journal of Heterocyclic Chemistry 56 (3), 795-803, 2019 | 12 | 2019 |
Utilization of cyanoacetohydrazide and 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride in the synthesis of some novel anti-proliferative heterocyclic compounds MH Hekal, YM Ali, FSM Abu El-Azm Synthetic Communications 50 (18), 2839-2852, 2020 | 10 | 2020 |
An efficient approach for the synthesis and antimicrobial evaluation of some new benzocoumarins and related compounds MH Hekal, FSM Abu El-Azm, SS Samir Synthetic Communications 51 (14), 2175-2186, 2021 | 9 | 2021 |
Recent developments in chemistry of phthalazines FSM Abu El‐Azm, MR Mahmoud, MH Hekal ChemInform 46 (43), no-no, 2015 | 9 | 2015 |
New 1, 3, 4-thiadiazoles as potential anticancer agents: pro-apoptotic, cell cycle arrest, molecular modelling, and ADMET profile MH Hekal, PS Farag, MM Hemdan, AA El-Sayed, AI Hassaballah, ... RSC advances 13 (23), 15810-15825, 2023 | 8 | 2023 |
Facile Synthesis and Anticancer Activity of Novel 4-Aminothieno [2, 3-d] pyrimidines and Triazolothienopyrimidines FSM Abu El-Azm, AT Ali, MH Hekal Organic Preparations and Procedures International 51 (6), 507-520, 2019 | 8 | 2019 |
New Benzochromeno[2,3-d]Pyrimidines and Benzochromenotriazolo[1,5-c]Pyrimidines as Potential Inhibitors of Topoisomerase II MH Hekal, SS Samir, YM Ali, WM El-Sayed Polycyclic Aromatic Compounds 42 (10), 7644-7660, 2022 | 6 | 2022 |