Bile acid signaling in neurodegenerative and neurological disorders SM Grant, S DeMorrow International Journal of Molecular Sciences 21 (17), 5982, 2020 | 130 | 2020 |
Bile acid signaling is involved in the neurological decline in a murine model of acute liver failure M McMillin, G Frampton, M Quinn, S Ashfaq, S Grant, S DeMorrow The American Journal of Pathology 186 (2), 312-323, 2016 | 117 | 2016 |
TGR 5 signaling reduces neuroinflammation during hepatic encephalopathy M McMillin, G Frampton, R Tobin, G Dusio, J Smith, H Shin, ... Journal of neurochemistry 135 (3), 565-576, 2015 | 116 | 2015 |
Bile acid-mediated sphingosine-1-phosphate receptor 2 signaling promotes neuroinflammation during hepatic encephalopathy in mice M McMillin, G Frampton, S Grant, S Khan, J Diocares, A Petrescu, A Wyatt, ... Frontiers in Cellular Neuroscience 11, 191, 2017 | 90 | 2017 |
Suppression of the HPA axis during cholestasis can be attributed to hypothalamic bile acid signaling M McMillin, G Frampton, M Quinn, A Divan, S Grant, N Patel, ... Molecular Endocrinology 29 (12), 1720-1730, 2015 | 86 | 2015 |
FXR-mediated cortical cholesterol accumulation contributes to the pathogenesis of type A hepatic encephalopathy M McMillin, S Grant, G Frampton, AD Petrescu, J Kain, E Williams, ... Cellular and Molecular Gastroenterology and Hepatology 6 (1), 47-63, 2018 | 41 | 2018 |
Direct comparison of the thioacetamide and azoxymethane models of type a hepatic encephalopathy in mice S Grant, M McMillin, G Frampton, AD Petrescu, E Williams, V Jaeger, ... Gene Expression 18 (3), 171, 2018 | 41 | 2018 |
Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice M McMillin, S Grant, G Frampton, S Andry, A Brown, S DeMorrow Journal of Neuroinflammation 13 (1), 1-12, 2016 | 32 | 2016 |
Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, ... Journal of neuroinflammation 16 (1), 1-15, 2019 | 27 | 2019 |
Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats M McMillin, S DeMorrow, S Glaser, J Venter, K Kyritsi, T Zhou, S Grant, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (5 …, 2017 | 27 | 2017 |
Thrombospondin-1 exacerbates acute liver failure and hepatic encephalopathy pathology in mice by activating transforming growth factor β1 B Jefferson, M Ali, S Grant, G Frampton, M Ploof, S Andry, S DeMorrow, ... The American Journal of Pathology 190 (2), 347-357, 2020 | 19 | 2020 |
Glucocorticoids cause gender-dependent reversal of hepatic fibrosis in the MDR2-knockout mouse model AD Petrescu, S Grant, G Frampton, J Kain, K Hadidi, E Williams, ... International journal of molecular sciences 18 (11), 2389, 2017 | 18 | 2017 |
The neuropeptide galanin is up-regulated during cholestasis and contributes to cholangiocyte proliferation M McMillin, G Frampton, S Grant, S DeMorrow The American journal of pathology 187 (4), 819-830, 2017 | 17 | 2017 |
The TGFβ1 receptor antagonist GW788388 reduces JNK activation and protects against acetaminophen hepatotoxicity in mice M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, ... Toxicological Sciences 170 (2), 549-561, 2019 | 16 | 2019 |
Gulf war illness-related chemicals increase CD11b/c+ monocyte infiltration into the liver and aggravate hepatic cholestasis in a rodent model AD Petrescu, S Grant, G Frampton, M McMillin, J Kain, M Kodali, ... Scientific reports 8 (1), 1-13, 2018 | 14 | 2018 |
Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis AD Petrescu, S Grant, E Williams, G Frampton, EH Reinhart, A Nguyen, ... Scientific reports 10 (1), 1-19, 2020 | 12 | 2020 |
Coordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in multidrug resistance protein 2 knockout mice AD Petrescu, S Grant, E Williams, G Frampton, N Parks, H Blaney, ... The American journal of pathology 190 (3), 586-601, 2020 | 10 | 2020 |
Bile Acid‐Mediated Accumulation of Brain Cholesterol Contributes to Hepatic Encephalopathy Due to Acute Liver Failure S DeMorrow, S Grant, G Frampton, M McMillin The FASEB Journal 31, 803.3-803.3, 2017 | 2 | 2017 |
Liver and Biliary Tract Physiology/Pathophysiology: Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in … M McMillin, S DeMorrow, S Glaser, J Venter, K Kyritsi, T Zhou, S Grant, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (5 …, 2017 | 1 | 2017 |
The specific serotonin reuptake inhibitors sertraline and fluoxetine promote tumor growth in a mouse xenograft model of cholangiocarcinoma M McMillin, J Smith, H Shin, G Frampton, A Petrescu, J Kain, A Wyatt, ... Matters 3 (9), e201706000003, 2017 | 1 | 2017 |