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Dr. Umed Singh
Dr. Umed Singh
Department of Chemistry, University of Iowa
在 uiowa.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cross-Dehydrogenative Coupling of Azoles with α-C(sp3)–H of Ethers and Thioethers under Metal-Free Conditions: Functionalization of H–N Azoles via C–H …
H Aruri, U Singh, S Sharma, S Gudup, M Bhogal, S Kumar, D Singh, ...
The Journal of Organic Chemistry 80 (3), 1929-1936, 2015
882015
Design of novel 3-pyrimidinylazaindole CDK2/9 inhibitors with potent in vitro and in vivo antitumor efficacy in a triple-negative breast cancer model
U Singh, G Chashoo, SU Khan, P Mahajan, A Nargotra, G Mahajan, ...
Journal of Medicinal Chemistry 60 (23), 9470-9489, 2017
632017
Iron oxide mediated direct C–H arylation/alkylation at α-position of cyclic aliphatic ethers
P PaláSingh
Chemical Communications 47 (20), 5852-5854, 2011
552011
I2/Aqueous TBHP-Catalyzed Coupling of Amides with Methylarenes/Aldehydes/Alcohols: Metal-Free Synthesis of Imides
H Aruri, U Singh, S Kumar, M Kushwaha, AP Gupta, RA Vishwakarma, ...
Organic letters 18 (15), 3638-3641, 2016
512016
Metal-free Cross-Dehydrogenative Coupling of HN-azoles with α-C(sp3)-H Amides via C–H Activation and Its Mechanistic and Application Studies
H Aruri, U Singh, M Kumar, S Sharma, SK Aithagani, VK Gupta, S Mignani, ...
The Journal of Organic Chemistry 82 (2), 1000-1012, 2017
452017
New method for C–H arylation/alkylation at α-position of cyclic aliphatic ethers by iron-oxide mediated reaction
PP Singh, S Gudup, H Aruri, U Singh, S Ambala, M Yadav, SD Sawant, ...
Organic & Biomolecular Chemistry 10 (8), 1587-1597, 2012
432012
Metal free C–H functionalization of diazines and related heteroarenes with organoboron species and its application in the synthesis of a CDK inhibitor, meriolin 1
T Thatikonda, U Singh, S Ambala, RA Vishwakarma, PP Singh
Organic & Biomolecular Chemistry 14 (18), 4312-4320, 2016
242016
Small molecule ‘4ab’induced autophagy and endoplasmic reticulum stress-mediated death of aggressive cancer cells grown under adherent and floating conditions
SU Khan, K Fatima, U Singh, PP Singh, F Malik
Medical Oncology 40 (4), 121, 2023
162023
A marine-based meriolin (3-pyrimidinylazaindole) derivative (4ab) targets PI3K/AKT/mTOR pathway inducing cell cycle arrest and apoptosis in Molt-4 cells
G Chashoo, U Singh, PP Singh, DM Mondhe, RA Vishwakarma
Clinical Cancer Drugs 6 (1), 33-40, 2019
72019
Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter
MM Hossain, A Khalid, Z Akhter, S Parveen, MO Ayaz, AQ Bhat, ...
Journal of Translational Medicine 22 (1), 370, 2024
12024
Inflated endoplasmic reticulum and autophagy induction promoted death in aggressive cancer cells grown in adherent and in-vitro CTC conditions.
SU Khan, K Fatima, U Singh, PP Singh, F Malik
12022
Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner
MO Ayaz, AQ Bhat, Z Akhter, N Badsera, MM Hossain, F Showket, ...
Life Sciences 351, 122840, 2024
2024
Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization
U Singh, G Pawge, S Rani, CHC Hsiao, AJ Wiemer, DF Wiemer
Journal of medicinal chemistry 66 (22), 15309-15325, 2023
2023
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