Selective vulnerability of cancer cells by inhibition of Ca2+ transfer from endoplasmic reticulum to mitochondria C Cárdenas, M Müller, A McNeal, A Lovy, F Jaňa, G Bustos, F Urra, ... Cell reports 14 (10), 2313-2324, 2016 | 255 | 2016 |
Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway V Parra, HE Verdejo, M Iglewski, A Del Campo, R Troncoso, D Jones, ... Diabetes 63 (1), 75-88, 2014 | 247 | 2014 |
Mitochondrial Ca2+ uniporter is a mitochondrial luminal redox sensor that augments MCU channel activity Z Dong, S Shanmughapriya, D Tomar, N Siddiqui, S Lynch, N Nemani, ... Molecular cell 65 (6), 1014-1028. e7, 2017 | 234 | 2017 |
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ... Cell reports 15 (8), 1673-1685, 2016 | 227 | 2016 |
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics A Carreras-Sureda, F Jana, H Urra, S Durand, DE Mortenson, A Sagredo, ... Nature cell biology 21 (6), 755-767, 2019 | 203 | 2019 |
Antiproliferative and uncoupling effects of delocalized, lipophilic, cationic gallic acid derivatives on cancer cell lines. Validation in vivo in singenic mice JA Jara, V Castro-Castillo, J Saavedra-Olavarría, L Peredo, M Pavanni, ... Journal of medicinal chemistry 57 (6), 2440-2454, 2014 | 110 | 2014 |
MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca2+ stress N Nemani, E Carvalho, D Tomar, Z Dong, A Ketschek, SL Breves, F Jaña, ... Cell reports 23 (4), 1005-1019, 2018 | 95 | 2018 |
Blockade of MCU-mediated Ca2+ uptake perturbs lipid metabolism via PP4-dependent AMPK dephosphorylation D Tomar, F Jaña, Z Dong, WJ Quinn, P Jadiya, SL Breves, CC Daw, ... Cell reports 26 (13), 3709-3725. e7, 2019 | 74 | 2019 |
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ... Science signaling 13 (640), eaay1212, 2020 | 54 | 2020 |
Trypanosoma cruzi induces apoptosis in ex vivo infected human chorionic villi J Duaso, G Rojo, F Jaña, N Galanti, G Cabrera, C Bosco, R López-Muñoz, ... Placenta 32 (5), 356-361, 2011 | 52 | 2011 |
KCTD5, a novel TRPM4‐regulatory protein required for cell migration as a new predictor for breast cancer prognosis J Rivas, N Díaz, I Silva, D Morales, B Lavanderos, A Álvarez, MP Saldías, ... The FASEB Journal 34 (6), 7847-7865, 2020 | 40 | 2020 |
Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson’s disease A Herrera, P Munoz, I Paris, G Díaz-Veliz, S Mora, J Inzunza, K Hultenby, ... Cellular and molecular life sciences 73, 3583-3597, 2016 | 39 | 2016 |
Role of matrix metalloproteinases 2 and 9 in ex vivo Trypanosoma cruzi infection of human placental chorionic villi C Castillo, R Lopez-Munoz, J Duaso, N Galanti, F Jaña, J Ferreira, ... Placenta 33 (12), 991-997, 2012 | 39 | 2012 |
An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G2/M-phase arrest in mammary … FA Urra, M Martínez-Cifuentes, M Pavani, M Lapier, F Jaña-Prado, ... Toxicology and applied pharmacology 267 (3), 218-227, 2013 | 37 | 2013 |
Court FA, Kroemer G, Cardenas JC, Hetz C (2019) Non-canonical function of IRE1alpha determines mitochondria-associated endoplasmic reticulum composition to control calcium … A Carreras-Sureda, F Jaña, H Urra, S Durand, DE Mortenson, A Sagredo, ... Nat Cell Biol 21 (6), 755-767, 0 | 37 | |
Prolonged activation of the Htr2b serotonin receptor impairs glucose stimulated insulin secretion and mitochondrial function in MIN6 cells LR Cataldo, ML Mizgier, R Bravo Sagua, F Jaña, C Cárdenas, P Llanos, ... PloS one 12 (1), e0170213, 2017 | 30 | 2017 |
Aged blood factors decrease cellular responses associated with delayed gingival wound repair MP Saldías, C Fernández, A Morgan, C Díaz, D Morales, F Jaña, ... PloS one 12 (9), e0184189, 2017 | 24 | 2017 |
Complex I and II are required for normal mitochondrial Ca2+ homeostasis F Jaña, G Bustos, J Rivas, P Cruz, F Urra, C Basualto-Alarcón, E Sagredo, ... Mitochondrion 49, 73-82, 2019 | 23 | 2019 |
Tumor cell death induced by the inhibition of mitochondrial electron transport: The effect of 3-hydroxybakuchiol F Jaña, F Faini, M Lapier, M Pavani, U Kemmerling, A Morello, JD Maya, ... Toxicology and applied pharmacology 272 (2), 356-364, 2013 | 19 | 2013 |
Mitochondrial dysfunction in human immunodeficiency virus‐1 transgenic mouse cardiac myocytes JY Cheung, J Gordon, JF Wang, J Song, XQ Zhang, FJ Prado, ... Journal of cellular physiology 234 (4), 4432-4444, 2019 | 16 | 2019 |