Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery K Stock, MF Estrada, S Vidic, K Gjerde, A Rudisch, VE Santo, M Barbier, ... Scientific reports 6 (1), 28951, 2016 | 243 | 2016 |
3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment SP Rebelo, C Pinto, TR Martins, N Harrer, MF Estrada, P Loza-Alvarez, ... Biomaterials 163, 185-197, 2018 | 202 | 2018 |
Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression MF Estrada, SP Rebelo, EJ Davies, MT Pinto, H Pereira, VE Santo, ... Biomaterials 78, 50-61, 2016 | 133 | 2016 |
Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models VE Santo, MF Estrada, SP Rebelo, S Abreu, I Silva, C Pinto, SC Veloso, ... Journal of biotechnology 221, 118-129, 2016 | 107 | 2016 |
Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read‐outs VE Santo, SP Rebelo, MF Estrada, PM Alves, E Boghaert, C Brito Biotechnology journal 12 (1), 1600505, 2017 | 104 | 2017 |
SPIM-fluid: open source light-sheet based platform for high-throughput imaging EJ Gualda, H Pereira, T Vale, MF Estrada, C Brito, N Moreno Biomedical optics express 6 (11), 4447-4456, 2015 | 79 | 2015 |
HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism SP Rebelo, R Costa, M Estrada, V Shevchenko, C Brito, PM Alves Archives of toxicology 89, 1347-1358, 2015 | 75 | 2015 |
Zebrafish avatars towards personalized medicine—a comparative review between avatar models B Costa, MF Estrada, RV Mendes, R Fior Cells 9 (2), 293, 2020 | 70 | 2020 |
Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression J Rosmaninho-Salgado, AP Marques, M Estrada, M Santana, V Cortez, ... Peptides 37 (1), 49-54, 2012 | 49 | 2012 |
Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project R De Hoogt, MF Estrada, S Vidic, EJ Davies, A Osswald, M Barbier, ... Scientific data 4 (1), 1-23, 2017 | 47 | 2017 |
Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes J Rosmaninho-Salgado, V Cortez, M Estrada, MM Santana, A Gonçalves, ... Neuropeptides 46 (6), 359-366, 2012 | 43 | 2012 |
Polymethoxylated flavones from orange peels inhibit cell proliferation in a 3D cell model of human colorectal cancer I Silva, MF Estrada, C V. Pereira, AB da Silva, MR Bronze, PM Alves, ... Nutrition and cancer 70 (2), 257-266, 2018 | 31 | 2018 |
Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line AP Marques, J Rosmaninho-Salgado, M Estrada, V Cortez, RJ Nobre, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (3), 673-682, 2017 | 24 | 2017 |
A novel culture method that sustains ERα signaling in human breast cancer tissue microstructures AL Cartaxo, MF Estrada, G Domenici, R Roque, F Silva, EJ Gualda, ... Journal of Experimental & Clinical Cancer Research 39, 1-14, 2020 | 22 | 2020 |
In vitro and ex vivo models–the tumor microenvironment in a flask C Pinto, MF Estrada, C Brito Tumor Microenvironment: The Main Driver of Metabolic Adaptation, 431-443, 2020 | 17 | 2020 |
Capturing tumor complexity in vitro: comparative analysis of 2D and 3D tumor models for drug discovery. Sci Rep 6: 28951 K Stock, MF Estrada, S Vidic, K Gjerde, A Rudisch, VE Santo, M Barbier, ... | 11 | 2016 |
Zebrafish Patient‐Derived Avatars from Digestive Cancers for Anti‐cancer Therapy Screening B Costa, MF Estrada, MT Barroso, R Fior Current Protocols 2 (4), e415, 2022 | 7 | 2022 |
PREDECT protocols for complex 2D/3D cultures S Vidic, MF Estrada, K Gjerde, VE Santo, A Osswald, M Barbier, ... Systems Chemical Biology: Methods and Protocols, 1-20, 2019 | 4 | 2019 |
Patient-Derived Breast Cancer Tissue Cultures for Anti-Endocrine Drug Assays G Domenici, G Trindade, MF Estrada, AL Cartaxo, PM Alves, S André, ... Cancer Drug Resistance: Methods and Protocols, 11-31, 2022 | 2 | 2022 |
The impact of co-culture of NSCLC tumor cells and fibroblasts on drug response S Abreu, VE Santo, A Oleksijew, E Oswald, MF Estrada, SP Rebelo, ... Annals of Oncology 28, v21, 2017 | 1 | 2017 |