Synthesis of nucleoside phosphate and phosphonate prodrugs U Pradere, EC Garnier-Amblard, SJ Coats, F Amblard, RF Schinazi Chemical reviews 114 (18), 9154-9218, 2014 | 624 | 2014 |
A small-molecule inhibitor of Lin28 M Roos, U Pradère, RP Ngondo, A Behera, S Allegrini, G Civenni, ... ACS chemical biology 11 (10), 2773-2781, 2016 | 155 | 2016 |
Preparation of ribavirin analogues by copper-and ruthenium-catalyzed azide-alkyne 1, 3-dipolar cycloaddition U Pradere, V Roy, TR McBrayer, RF Schinazi, LA Agrofoglio Tetrahedron 64 (38), 9044-9051, 2008 | 101 | 2008 |
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates D Topalis, U Pradere, V Roy, C Caillat, A Azzouzi, J Broggi, R Snoeck, ... Journal of medicinal chemistry 54 (1), 222-232, 2011 | 66 | 2011 |
β-d-2′-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted … L Zhou, H Zhang, S Tao, L Bassit, T Whitaker, TR McBrayer, M Ehteshami, ... Journal of medicinal chemistry 58 (8), 3445-3458, 2015 | 54 | 2015 |
Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis H Kumamoto, D Topalis, J Broggi, U Pradere, V Roy, S Berteina-Raboin, ... Tetrahedron 64 (16), 3517-3526, 2008 | 51 | 2008 |
Purine monophosphate prodrugs for treatment of viral infections RF Schinazi, JH Cho, L Zhou, H Zhang, U Pradere, SJ Coats US Patent App. 14/117,815, 2014 | 49 | 2014 |
Expeditious convergent procedure for the preparation of bis (POC) prodrugs of new (E)-4-phosphono-but-2-en-1-yl nucleosides A Montagu, U Pradére, V Roy, SP Nolan, LA Agrofoglio Tetrahedron 67 (29), 5319-5328, 2011 | 47 | 2011 |
Synthesis of 5′-Methylene-Phosphonate Furanonucleoside Prodrugs: Application to D-2′-Deoxy-2′-α-fluoro-2′-β-C-methyl Nucleosides U Pradere, F Amblard, SJ Coats, RF Schinazi Organic Letters 14 (17), 4426-4429, 2012 | 42 | 2012 |
Chemical Synthesis of Mono‐and Bis‐Labeled Pre‐MicroRNAs U Pradère, A Brunschweiger, LFR Gebert, M Lucic, M Roos, J Hall Angewandte Chemie International Edition, 12028-12032, 2013 | 40 | 2013 |
Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain M Koch, J Willi, U Pradere, J Hall, N Polacek Nucleic acids research 45 (11), 6717-6728, 2017 | 34 | 2017 |
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells M Roos, MAE Rebhan, M Lucic, D Pavlicek, U Pradere, H Towbin, ... Nucleic acids research 43 (2), e9-e9, 2015 | 33 | 2015 |
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors L Bondada, R Rondla, U Pradere, P Liu, C Li, D Bobeck, T McBrayer, ... Bioorganic & medicinal chemistry letters 23 (23), 6325-6330, 2013 | 23 | 2013 |
Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3′-azido-2′, 3′-dideoxyguanosine-5′-triphosphates as adenosine analogs BD Herman, RF Schinazi, H Zhang, JH Nettles, R Stanton, M Detorio, ... Nucleic acids research 40 (1), 381-390, 2012 | 22 | 2012 |
The shortest strategy for generating phosphonate prodrugs by olefin cross‐metathesis–Application to acyclonucleoside phosphonates U Pradère, H Clavier, V Roy, SP Nolan, LA Agrofoglio European Journal of Organic Chemistry 2011 (36), 7324-7330, 2011 | 22 | 2011 |
Site-specific difunctionalization of structured RNAs yields probes for microRNA maturation U Pradère, J Hall Bioconjugate chemistry 27 (3), 681-687, 2016 | 21 | 2016 |
One-and two-dimensional high-resolution NMR from flat surfaces BJ Walder, C Berk, WC Liao, AJ Rossini, M Schwarzwälder, U Pradere, ... ACS central science 5 (3), 515-523, 2019 | 19 | 2019 |
Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC A Brunschweiger, LFR Gebert, M Lucic, U Pradère, H Jahns, C Berk, ... Chemical Communications 52 (1), 156-159, 2016 | 19 | 2016 |
Synthesis and antiviral evaluation of bis (POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl] purine nucleosides U Pradère, V Roy, A Montagu, O Sari, M Hamada, J Balzarini, R Snoeck, ... European journal of medicinal chemistry 57, 126-133, 2012 | 18 | 2012 |
Chemical synthesis of long RNAs with terminal 5′‐phosphate groups U Pradère, F Halloy, J Hall Chemistry–A European Journal 23 (22), 5210-5213, 2017 | 17 | 2017 |