关注
Ugo Pradere
Ugo Pradere
Senior Scientist in Pharmaceutical Chemistry, ETH Zurich
在 pharma.ethz.ch 的电子邮件经过验证
标题
引用次数
引用次数
年份
Synthesis of nucleoside phosphate and phosphonate prodrugs
U Pradere, EC Garnier-Amblard, SJ Coats, F Amblard, RF Schinazi
Chemical reviews 114 (18), 9154-9218, 2014
6242014
A small-molecule inhibitor of Lin28
M Roos, U Pradère, RP Ngondo, A Behera, S Allegrini, G Civenni, ...
ACS chemical biology 11 (10), 2773-2781, 2016
1552016
Preparation of ribavirin analogues by copper-and ruthenium-catalyzed azide-alkyne 1, 3-dipolar cycloaddition
U Pradere, V Roy, TR McBrayer, RF Schinazi, LA Agrofoglio
Tetrahedron 64 (38), 9044-9051, 2008
1012008
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates
D Topalis, U Pradere, V Roy, C Caillat, A Azzouzi, J Broggi, R Snoeck, ...
Journal of medicinal chemistry 54 (1), 222-232, 2011
662011
β-d-2′-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted …
L Zhou, H Zhang, S Tao, L Bassit, T Whitaker, TR McBrayer, M Ehteshami, ...
Journal of medicinal chemistry 58 (8), 3445-3458, 2015
542015
Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis
H Kumamoto, D Topalis, J Broggi, U Pradere, V Roy, S Berteina-Raboin, ...
Tetrahedron 64 (16), 3517-3526, 2008
512008
Purine monophosphate prodrugs for treatment of viral infections
RF Schinazi, JH Cho, L Zhou, H Zhang, U Pradere, SJ Coats
US Patent App. 14/117,815, 2014
492014
Expeditious convergent procedure for the preparation of bis (POC) prodrugs of new (E)-4-phosphono-but-2-en-1-yl nucleosides
A Montagu, U Pradére, V Roy, SP Nolan, LA Agrofoglio
Tetrahedron 67 (29), 5319-5328, 2011
472011
Synthesis of 5′-Methylene-Phosphonate Furanonucleoside Prodrugs: Application to D-2′-Deoxy-2′-α-fluoro-2′-β-C-methyl Nucleosides
U Pradere, F Amblard, SJ Coats, RF Schinazi
Organic Letters 14 (17), 4426-4429, 2012
422012
Chemical Synthesis of Mono‐and Bis‐Labeled Pre‐MicroRNAs
U Pradère, A Brunschweiger, LFR Gebert, M Lucic, M Roos, J Hall
Angewandte Chemie International Edition, 12028-12032, 2013
402013
Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain
M Koch, J Willi, U Pradere, J Hall, N Polacek
Nucleic acids research 45 (11), 6717-6728, 2017
342017
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells
M Roos, MAE Rebhan, M Lucic, D Pavlicek, U Pradere, H Towbin, ...
Nucleic acids research 43 (2), e9-e9, 2015
332015
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors
L Bondada, R Rondla, U Pradere, P Liu, C Li, D Bobeck, T McBrayer, ...
Bioorganic & medicinal chemistry letters 23 (23), 6325-6330, 2013
232013
Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3′-azido-2′, 3′-dideoxyguanosine-5′-triphosphates as adenosine analogs
BD Herman, RF Schinazi, H Zhang, JH Nettles, R Stanton, M Detorio, ...
Nucleic acids research 40 (1), 381-390, 2012
222012
The shortest strategy for generating phosphonate prodrugs by olefin cross‐metathesis–Application to acyclonucleoside phosphonates
U Pradère, H Clavier, V Roy, SP Nolan, LA Agrofoglio
European Journal of Organic Chemistry 2011 (36), 7324-7330, 2011
222011
Site-specific difunctionalization of structured RNAs yields probes for microRNA maturation
U Pradère, J Hall
Bioconjugate chemistry 27 (3), 681-687, 2016
212016
One-and two-dimensional high-resolution NMR from flat surfaces
BJ Walder, C Berk, WC Liao, AJ Rossini, M Schwarzwälder, U Pradere, ...
ACS central science 5 (3), 515-523, 2019
192019
Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC
A Brunschweiger, LFR Gebert, M Lucic, U Pradère, H Jahns, C Berk, ...
Chemical Communications 52 (1), 156-159, 2016
192016
Synthesis and antiviral evaluation of bis (POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl] purine nucleosides
U Pradère, V Roy, A Montagu, O Sari, M Hamada, J Balzarini, R Snoeck, ...
European journal of medicinal chemistry 57, 126-133, 2012
182012
Chemical synthesis of long RNAs with terminal 5′‐phosphate groups
U Pradère, F Halloy, J Hall
Chemistry–A European Journal 23 (22), 5210-5213, 2017
172017
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