A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers LC Tan, N Gudgeon, NE Annels, P Hansasuta, CA O’Callaghan, ... The Journal of Immunology 162 (3), 1827-1835, 1999 | 609 | 1999 |
Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection N Khan, A Hislop, N Gudgeon, M Cobbold, R Khanna, L Nayak, ... The Journal of Immunology 173 (12), 7481-7489, 2004 | 439 | 2004 |
Epitope-specific evolution of human CD8+ T cell responses from primary to persistent phases of Epstein-Barr virus infection AD Hislop, NE Annels, NH Gudgeon, AM Leese, AB Rickinson The Journal of experimental medicine 195 (7), 893, 2002 | 390 | 2002 |
Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection E Amyes, C Hatton, D Montamat-Sicotte, N Gudgeon, AB Rickinson, ... The Journal of experimental medicine 198 (6), 903, 2003 | 287 | 2003 |
EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function AD Hislop, NH Gudgeon, MFC Callan, C Fazou, H Hasegawa, M Salmon, ... The Journal of Immunology 167 (4), 2019-2029, 2001 | 271 | 2001 |
Epstein-Barr virus–specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential PJ Dunne, JM Faint, NH Gudgeon, JM Fletcher, FJ Plunkett, MVD Soares, ... Blood, The Journal of the American Society of Hematology 100 (3), 933-940, 2002 | 194 | 2002 |
CD4+ T-Cell Responses to Epstein-Barr Virus (EBV) Latent-Cycle Antigens and the Recognition of EBV-Transformed Lymphoblastoid Cell Lines HM Long, TA Haigh, NH Gudgeon, AM Leen, CW Tsang, J Brooks, ... Journal of virology 79 (8), 4896-4907, 2005 | 181 | 2005 |
Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype MK Maini, N Gudgeon, LR Wedderburn, AB Rickinson, PCL Beverley The Journal of Immunology 165 (10), 5729-5737, 2000 | 167 | 2000 |
Dual Stimulation of Epstein-Barr Virus (EBV)-Specific CD4+- and CD8+-T-Cell Responses by a Chimeric Antigen Construct: Potential Therapeutic Vaccine for EBV … GS Taylor, TA Haigh, NH Gudgeon, RJ Phelps, SP Lee, NM Steven, ... Journal of virology 78 (2), 768-778, 2004 | 162 | 2004 |
CD4 and CD8 T cell responses to tumour-associated Epstein–Barr virus antigens in nasopharyngeal carcinoma patients X Lin, NH Gudgeon, EP Hui, H Jia, X Qun, GS Taylor, MCNM Barnardo, ... Cancer Immunology, Immunotherapy 57, 963-975, 2008 | 63 | 2008 |
Regression of Epstein-Barr Virus-Induced B-Cell Transformation In Vitro Involves Virus-Specific CD8+ T Cells as the Principal Effectors and a Novel CD4+ T-Cell … NH Gudgeon, GS Taylor, HM Long, TA Haigh, AB Rickinson Journal of virology 79 (9), 5477-5488, 2005 | 56 | 2005 |
CD4+ T-cell clones recognizing human lymphoma-associated antigens: generation by in vitro stimulation with autologous Epstein-Barr virus–transformed B cells HM Long, J Zuo, AM Leese, NH Gudgeon, H Jia, GS Taylor, AB Rickinson Blood, The Journal of the American Society of Hematology 114 (4), 807-815, 2009 | 39 | 2009 |
CD4+ T-Cell Responses to Epstein-Barr Virus Nuclear Antigen EBNA1 in Chinese Populations Are Highly Focused on Novel C-Terminal Domain-Derived Epitopes CW Tsang, X Lin, NH Gudgeon, GS Taylor, H Jia, EP Hui, ATC Chan, ... Journal of virology 80 (16), 8263-8266, 2006 | 35 | 2006 |
Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation N Gudgeon, H Munford, EL Bishop, J Hill, T Fulton-Ward, D Bending, ... Cell Reports 40 (7), 2022 | 31 | 2022 |
Control of T cell metabolism by cytokines and hormones EL Bishop, N Gudgeon, S Dimeloe Frontiers in immunology 12, 653605, 2021 | 31 | 2021 |
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity BJ Jenkins, J Blagih, FM Ponce-Garcia, M Canavan, N Gudgeon, ... Cell Metabolism 35 (7), 1132-1146. e9, 2023 | 28 | 2023 |
1,25‐Dihydroxyvitamin D3 suppresses CD4+ T‐cell effector functionality by inhibition of glycolysis EL Bishop, NH Gudgeon, GM Mackie, D Chauss, J Roberts, DA Tennant, ... Immunology 166 (3), 299-309, 2022 | 9 | 2022 |
Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma N Gudgeon, H Giles, EL Bishop, T Fulton-Ward, C Escribano-Gonzalez, ... Blood Advances 7 (20), 6035-6047, 2023 | 2 | 2023 |
TNF-α signals through ITK-Akt-mTOR to drive CD4+ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis EL Bishop, N Gudgeon, T Fulton-Ward, V Stavrou, J Roberts, ... Science signaling 17 (833), eadg5678, 2024 | | 2024 |
Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells MR Teh, N Gudgeon, JN Frost, LV Sinclair, AL Smith, CL Millington, ... bioRxiv, 2024.02. 01.578381, 2024 | | 2024 |