SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth SH Park, O Ozden, G Liu, HY Song, Y Zhu, Y Yan, X Zou, HJ Kang, ... Cancer research 76 (13), 3802-3812, 2016 | 114 | 2016 |
Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model TZ Minas, D Surdez, T Javaheri, M Tanaka, M Howarth, HJ Kang, J Han, ... Oncotarget 8 (21), 34141, 2017 | 92 | 2017 |
A multifunctional protein, EWS, is essential for early brown fat lineage determination JH Park, HJ Kang, S Im Kang, JE Lee, J Hur, K Ge, E Mueller, H Li, ... Developmental cell 26 (4), 393-404, 2013 | 88 | 2013 |
SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a MJ Kim, K Ahn, SH Park, HJ Kang, BG Jang, SJ Oh, SM Oh, YJ Jeong, ... FEBS letters 583 (7), 1183-1188, 2009 | 69 | 2009 |
EWS–WT1 oncoprotein activates neuronal reprogramming factor ASCL1 and promotes neural differentiation HJ Kang, JH Park, WP Chen, SI Kang, K Moroz, M Ladanyi, SB Lee Cancer research 74 (16), 4526-4535, 2014 | 42 | 2014 |
Neuronal loss in primary long-term cortical culture involves neurodegeneration-like cell death via calpain and p35 processing, but not developmental apoptosis or aging MJ Kim, SJ Oh, SH Park, HJ Kang, MH Won, TC Kang, JB Park, JI Kim, ... Experimental & molecular medicine 39 (1), 14-26, 2007 | 40 | 2007 |
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status HY Song, M Biancucci, HJ Kang, C O'Callaghan, SH Park, DR Principe, ... Oncotarget 7 (49), 80336, 2016 | 37 | 2016 |
Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis JH Park, HJ Kang, YK Lee, H Kang, J Kim, JH Chung, JS Chang, ... Proceedings of the National Academy of Sciences 112 (19), 6074-6079, 2015 | 34 | 2015 |
Effect of combined treatment with progesterone and tamoxifen on the growth and apoptosis of human ovarian cancer cells JY Lee, JY Shin, HS Kim, JI Heo, YJ Kho, HJ Kang, SH Park, JY Lee Oncology reports 27 (1), 87-93, 2012 | 33 | 2012 |
Calorie restriction (CR) reduces age-dependent decline of non-homologous end joining (NHEJ) activity in rat tissues JE Lee, JI Heo, SH Park, JH Kim, YJ Kho, HJ Kang, HY Chung, JL Yoon, ... Experimental gerontology 46 (11), 891-896, 2011 | 30 | 2011 |
ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage JI Heo, SJ Oh, YJ Kho, JH Kim, HJ Kang, SH Park, HS Kim, JY Shin, ... Molecular biology reports 39, 8007-8014, 2012 | 27 | 2012 |
ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21Waf1/Cip1/Sdi in response to DNA damage in normal human … JI Heo, SJ Oh, YJ Kho, JH Kim, HJ Kang, SH Park, HS Kim, JY Shin, ... Molecular biology reports 38, 2785-2791, 2011 | 24 | 2011 |
Nicotinamide reduces dopamine in postnatal hypothalamus and causes dopamine-deficient phenotype JY Lee, K Ahn, BG Jang, SH Park, HJ Kang, JI Heo, YJ Ko, MH Won, ... Neuroscience letters 461 (2), 163-166, 2009 | 24 | 2009 |
Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages WS Hwang, SH Park, HS Kim, HJ Kang, MJ Kim, SJ Oh, JB Park, J Kim, ... Nutrition Research and Practice 1 (2), 105-112, 2007 | 23 | 2007 |
Nitric oxide is an essential mediator for neuronal differentiation of rat primary cortical neuron cells SJ Oh, JI Heo, YJ Kho, JH Kim, HJ Kang, SH Park, HS Kim, JY Shin, ... Experimental Neurobiology 19 (2), 83, 2010 | 20 | 2010 |
Hypoxia-induced cell death of HepG2 cells involves a necrotic cell death mediated by calpain MJ Kim, SJ Oh, SH Park, HJ Kang, MH Won, TC Kang, IK Hwang, JB Park, ... Apoptosis 12, 707-718, 2007 | 20 | 2007 |
Transcriptional activation of p21WAF1/CIP1 is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation … HS Kim, JI Heo, SH Park, JY Shin, HJ Kang, MJ Kim, SC Kim, J Kim, ... Molecular biology reports 41, 2397-2408, 2014 | 18 | 2014 |
Salt-inducible kinase 1 is a potential therapeutic target in desmoplastic small round cell tumor AB Hartono, HJ Kang, L Shi, W Phipps, N Ungerleider, A Giardina, ... Oncogenesis 11 (1), 18, 2022 | 12 | 2022 |
NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity HJ Kang, HY Song, MA Ahmed, Y Guo, M Zhang, C Chen, M Cristofanilli, ... Free Radical Biology and Medicine 126, 358-371, 2018 | 12 | 2018 |
Higher DNA repair activity is related with longer replicative life span in mammalian embryonic fibroblast cells SH Park, HJ Kang, HS Kim, MJ Kim, JI Heo, JH Kim, YJ Kho, SC Kim, ... Biogerontology 12, 565-579, 2011 | 11 | 2011 |