Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ... Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012 | 459 | 2012 |
Discovering new medicines targeting helicases: challenges and recent progress WR Shadrick, J Ndjomou, R Kolli, S Mukherjee, AM Hanson, DN Frick Journal of biomolecular screening 18 (7), 761-781, 2013 | 116 | 2013 |
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication S Mukherjee, WS Weiner, CE Schroeder, DS Simpson, AM Hanson, ... ACS chemical biology 9 (10), 2393-2403, 2014 | 87 | 2014 |
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ... Journal of Medicinal Chemistry 55 (7), 3319-3330, 2012 | 75 | 2012 |
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ... ACS infectious diseases 1 (3), 140-148, 2015 | 60 | 2015 |
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays S Mukherjee, AM Hanson, WR Shadrick, J Ndjomou, NL Sweeney, ... Nucleic Acids Research 40 (17), 8607-8621, 2012 | 58 | 2012 |
Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP WR Shadrick, S Mukherjee, AM Hanson, NL Sweeney, DN Frick Biochemistry 52 (36), 6151-6159, 2013 | 41 | 2013 |
Identification and analysis of inhibitors targeting the hepatitis C virus NS3 helicase AM Hanson, JJ Hernandez, WR Shadrick, DN Frick Methods in enzymology 511, 463-483, 2012 | 26 | 2012 |
The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities C Aydin, S Mukherjee, AM Hanson, DN Frick, CA Schiffer Protein Science 22 (12), 1786-1798, 2013 | 25 | 2013 |
Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation J Ndjomou, R Kolli, S Mukherjee, WR Shadrick, AM Hanson, NL Sweeney, ... Antiviral research 96 (2), 245-255, 2012 | 24 | 2012 |
A–C Estrogens as potent and selective estrogen receptor-beta agonists (SERBAs) to enhance memory consolidation under low-estrogen conditions AM Hanson, KLIS Perera, J Kim, RK Pandey, N Sweeney, X Lu, A Imhoff, ... Journal of medicinal chemistry 61 (11), 4720-4738, 2018 | 22 | 2018 |
Long-term oral administration of a novel estrogen receptor beta agonist enhances memory and alleviates drug-induced vasodilation in young ovariectomized mice AW Fleischer, JC Schalk, EA Wetzel, AM Hanson, DS Sem, ... Hormones and behavior 130, 104948, 2021 | 17 | 2021 |
Docking into Mycobacterium tuberculosis Thioredoxin Reductase Protein Yields Pyrazolone Lead Molecules for Methicillin-Resistant Staphylococcus aureus NL Sweeney, L Lipker, AM Hanson, CJ Bohl, KE Engel, KS Kalous, ... Antibiotics 6 (1), 4, 2017 | 15 | 2017 |
Virus morphological diversity and relationship to bacteria and chlorophyll across a freshwater trophic gradient in the Lake Michigan watershed AM Hanson, JA Berges, EB Young Hydrobiologia 794, 93-108, 2017 | 14 | 2017 |
Simultaneously targeting the NS3 protease and helicase activities for more effective hepatitis C virus therapy J Ndjomou, MJ Corby, NL Sweeney, AM Hanson, C Aydin, A Ali, ... ACS chemical biology 10 (8), 1887-1896, 2015 | 11 | 2015 |
Hepatitis C virus NS3 helicase inhibitor discovery K Li, KJ Frankowski, AM Hanson, J Ndjomou, MA Shanahan, S Mukherjee, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2013 | 10 | 2013 |
Cultivation of Lemon Basil, Ocimum americanum, in two different hydroponic configurations supplemented with various concentrations of Tilapia aquaculture green water A Hanson, J Yabes, LP Primavera Bios 79 (3), 92-102, 2008 | 8 | 2008 |
Synthesis and evaluation of 17α-triazolyl and 9α-cyano derivatives of estradiol EA Wetzel, AM Hanson, CL Troutfetter, DJ Burkett, DS Sem, ... Bioorganic & medicinal chemistry 28 (19), 115670, 2020 | 4 | 2020 |
Synthesis and evaluation of 4-cycloheptylphenols as selective Estrogen receptor-β agonists (SERBAs) KLIS Perera, AM Hanson, S Lindeman, A Imhoff, X Lu, DS Sem, ... European Journal of Medicinal Chemistry 157, 791-804, 2018 | 4 | 2018 |
Analysis of the enzymatic activity of an NS3 helicase genotype 3a variant sequence obtained from a relapse patient PJS Provazzi, S Mukherjee, AM Hanson, ML Nogueira, BM Carneiro, ... PloS one 10 (12), e0144638, 2015 | 4 | 2015 |