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Christian Beusch
Christian Beusch
Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet
在 ki.se 的电子邮件经过验证
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引用次数
引用次数
年份
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ...
Journal of proteome research 18 (11), 4027-4037, 2019
1772019
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin
AA Saei, H Gullberg, P Sabatier, CM Beusch, K Johansson, B Lundgren, ...
Redox biology 32, 101491, 2020
712020
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ...
Nature communications 10 (1), 5715, 2019
622019
System-wide identification and prioritization of enzyme substrates by thermal analysis
AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ...
Nature communications 12 (1), 1296, 2021
55*2021
Quantitative selection analysis of bacteriophage φCbK susceptibility in Caulobacter crescentus
M Christen, C Beusch, Y Bösch, D Cerletti, CE Flores-Tinoco, ...
Journal of molecular biology 428 (2), 419-430, 2016
462016
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis
Y He, C Ge, À Moreno-Giró, B Xu, CM Beusch, K Sandor, J Su, L Cheng, ...
Nature communications 14 (1), 691, 2023
292023
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin
P Sabatier, CM Beusch, R Gencheva, Q Cheng, R Zubarev, ESJ Arnér
Redox Biology 48, 102184, 2021
252021
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ...
Nature communications 12 (1), 6558, 2021
202021
Ion-based proteome-integrated solubility alteration assays for systemwide profiling of protein–molecule interactions
CM Beusch, P Sabatier, RA Zubarev
Analytical Chemistry 94 (19), 7066-7074, 2022
192022
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
SC Wright, A Motso, S Koutsilieri, CM Beusch, P Sabatier, A Berghella, ...
Nature communications 14 (1), 6243, 2023
122023
System-wide profiling by proteome integral solubility alteration assay of drug residence times for target characterization
P Sabatier, CM Beusch, Z Meng, RA Zubarev
Analytical Chemistry 94 (45), 15772-15780, 2022
72022
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice
M Aoun, A Coelho, A Krämer, A Saxena, P Sabatier, CM Beusch, ...
Journal of Experimental Medicine 220 (11), e20230101, 2023
52023
Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes
N Oliva-Vilarnau, CM Beusch, P Sabatier, E Sakaraki, A Tjaden, L Graetz, ...
Hepatology, 10.1097, 2023
42023
Ultralight ultrafast enzymes
X Zhang, Z Meng, C Beusch, H Gharibi, Q Cheng, L Stefano, J Wang, ...
42021
Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis
V Urbonaviciute, L Romero-Castillo, B Xu, H Luo, N Schneider, S Weisse, ...
Proceedings of the National Academy of Sciences 120 (25), e2218668120, 2023
32023
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates
AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ...
32021
Ultralight Ultrafast Enzymes
X Zhang, Z Meng, CM Beusch, H Gharibi, Q Cheng, H Lyu, L Di Stefano, ...
Angewandte Chemie 136 (3), e202316488, 2024
12024
Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies
CM Beusch, OE Simonson, JO Wedin, P Sabatier, U Felldin, S Kadekar, ...
Cellular and Molecular Life Sciences 80 (9), 268, 2023
12023
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence
Z Strongin, L Raymond Marchand, C Deleage, MB Pampena, ...
Nature Immunology, 1-12, 2024
2024
Copper (I)-nitrene platform for chemoproteomic profiling of methionine
S Sahu, B Emenike, CM Beusch, P Bagchi, DE Gordon, M Raj
Nature Communications 15 (1), 4243, 2024
2024
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