Tcf4 regulates synaptic plasticity, DNA methylation, and memory function AJ Kennedy, EJ Rahn, BS Paulukaitis, KE Savell, HB Kordasiewicz, ... Cell reports 16 (10), 2666-2685, 2016 | 128 | 2016 |
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells AJ Kennedy, TP Mathews, Y Kharel, SD Field, ML Moyer, JE East, ... Journal of medicinal chemistry 54 (10), 3524-3548, 2011 | 99 | 2011 |
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder BDN Phan, JF Bohlen, BA Davis, Z Ye, HY Chen, B Mayfield, SR Sripathy, ... Nature neuroscience 23 (3), 375-385, 2020 | 96 | 2020 |
Learning and age-related changes in genome-wide H2A. Z binding in the mouse hippocampus G Stefanelli, AB Azam, BJ Walters, MA Brimble, CP Gettens, ... Cell reports 22 (5), 1124-1131, 2018 | 92 | 2018 |
Cytosine-based TET enzyme inhibitors GNL Chua, KL Wassarman, H Sun, JA Alp, EI Jarczyk, NJ Kuzio, ... ACS medicinal chemistry letters 10 (2), 180-185, 2019 | 83 | 2019 |
DNA methylation and its implications and accessibility for neuropsychiatric therapeutics JJ Day, AJ Kennedy, JD Sweatt Annual review of pharmacology and toxicology 55 (1), 591-611, 2015 | 77 | 2015 |
Discovery, biological evaluation, and structure− activity relationship of amidine based sphingosine kinase inhibitors TP Mathews, AJ Kennedy, Y Kharel, PC Kennedy, O Nicoara, M Sunkara, ... Journal of medicinal chemistry 53 (7), 2766-2778, 2010 | 75 | 2010 |
The use of eye-tracking to explore social difficulties in cognitively able students with autism spectrum disorder: A pilot investigation M Hanley, DM Riby, C Carty, A Melaugh McAteer, A Kennedy, ... Autism 19 (7), 868-873, 2015 | 72 | 2015 |
Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model CA Warren, E van Opstal, TE Ballard, A Kennedy, X Wang, M Riggins, ... Antimicrobial agents and chemotherapy 56 (8), 4103-4111, 2012 | 71 | 2012 |
Experience-dependent epigenomic reorganization in the hippocampus CG Duke, AJ Kennedy, CF Gavin, JJ Day, JD Sweatt Learning & memory 24 (7), 278-288, 2017 | 69 | 2017 |
Tet1 oxidase regulates neuronal gene transcription, active DNA hydroxymethylation, object location memory, and threat recognition memory D Kumar, M Aggarwal, GA Kaas, J Lewis, J Wang, DL Ross, C Zhong, ... Neuroepigenetics 4, 12-27, 2015 | 58 | 2015 |
Hippocampal transcriptomic profiles: subfield vulnerability to age and cognitive impairment L Ianov, M De Both, MK Chawla, A Rani, AJ Kennedy, I Piras, JJ Day, ... Frontiers in aging neuroscience 9, 383, 2017 | 51 | 2017 |
Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells JE East, AJ Kennedy, TJ Webb Medicinal research reviews 34 (1), 45-76, 2014 | 43 | 2014 |
Pitt–Hopkins mouse model has altered particular gastrointestinal transits in vivo V Grubišić, AJ Kennedy, JD Sweatt, V Parpura Autism Research 8 (5), 629-633, 2015 | 38 | 2015 |
Tet1 isoforms differentially regulate gene expression, synaptic transmission, and memory in the mammalian brain CB Greer, J Wright, JD Weiss, RM Lazarenko, SP Moran, J Zhu, ... Journal of Neuroscience 41 (4), 578-593, 2021 | 35 | 2021 |
Synthesis and structure–activity relationships of tyrosine-based inhibitors of autotaxin (ATX) JE East, AJ Kennedy, JL Tomsig, AR De Leon, KR Lynch, TL Macdonald Bioorganic & medicinal chemistry letters 20 (23), 7132-7136, 2010 | 35 | 2010 |
A rapid assay for assessment of sphingosine kinase inhibitors and substrates Y Kharel, TP Mathews, AJ Kennedy, JD Houck, TL Macdonald, KR Lynch Analytical biochemistry 411 (2), 230-235, 2011 | 34 | 2011 |
Generic and customised digital image enhancement filters for the visually impaired SJ Leat, G Omoruyi, A Kennedy, E Jernigan Vision research 45 (15), 1991-2007, 2005 | 34 | 2005 |
Methods and systems for analyzing nucleic acid molecules A Kennedy, SAW Mortimer, H Eltoukhy, AA Talasaz US Patent 11,519,019, 2022 | 23 | 2022 |
Drugging the methylome: DNA methylation and memory AJ Kennedy, JD Sweatt Critical reviews in biochemistry and molecular biology 51 (3), 185-194, 2016 | 23 | 2016 |