A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ... Nature genetics 47 (6), 615-624, 2015 | 258 | 2015 |
MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression S Nam, M Li, K Choi, C Balch, S Kim, KP Nephew Nucleic acids research 37 (suppl_2), W356-W362, 2009 | 200 | 2009 |
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies MA Smith, GS Choudhary, A Pellagatti, K Choi, LC Bolanos, TD Bhagat, ... Nature cell biology 21 (5), 640-650, 2019 | 191 | 2019 |
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis EP Rahrmann, AL Watson, VW Keng, K Choi, BS Moriarity, DA Beckmann, ... Nature genetics 45 (7), 756-766, 2013 | 180 | 2013 |
Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs T Muto, CS Walker, K Choi, K Hueneman, MA Smith, Z Gul, ... Nature immunology 21 (5), 535-545, 2020 | 124 | 2020 |
Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance AL Watson, EP Rahrmann, BS Moriarity, K Choi, CB Conboy, AD Greeley, ... Cancer discovery 3 (6), 674-689, 2013 | 115 | 2013 |
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia J Fang, LC Bolanos, K Choi, X Liu, S Christie, S Akunuru, R Kumar, ... Nature immunology 18 (2), 236-245, 2017 | 109 | 2017 |
Programming of Schwann cells by Lats1/2-TAZ/YAP signaling drives malignant peripheral nerve sheath tumorigenesis LMN Wu, Y Deng, J Wang, C Zhao, J Wang, R Rao, L Xu, W Zhou, K Choi, ... Cancer Cell 33 (2), 292-308. e7, 2018 | 84 | 2018 |
Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK A Ramkissoon, KE Chaney, D Milewski, KB Williams, RL Williams, K Choi, ... Clinical Cancer Research 25 (13), 4117-4127, 2019 | 74 | 2019 |
TRAF6 mediates basal activation of NF-κB necessary for hematopoietic stem cell homeostasis J Fang, T Muto, M Kleppe, LC Bolanos, KM Hueneman, CS Walker, ... Cell reports 22 (5), 1250-1262, 2018 | 70 | 2018 |
Overcoming adaptive therapy resistance in AML by targeting immune response pathways K Melgar, MM Walker, LQM Jones, LC Bolanos, K Hueneman, ... Science translational medicine 11 (508), eaaw8828, 2019 | 63 | 2019 |
Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia TM Chlon, E Stepanchick, CE Hershberger, NJ Daniels, KM Hueneman, ... Cell Stem Cell 28 (11), 1966-1981. e6, 2021 | 60 | 2021 |
Insertional mutagenesis identifies a STAT3/Arid1b/β-catenin pathway driving neurofibroma initiation J Wu, VW Keng, DM Patmore, JJ Kendall, AV Patel, E Jousma, WJ Jessen, ... Cell reports 14 (8), 1979-1990, 2016 | 60 | 2016 |
STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma JS Fletcher, MG Springer, K Choi, E Jousma, TA Rizvi, E Dombi, MO Kim, ... Oncogene 38 (15), 2876-2884, 2019 | 57 | 2019 |
Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation SK Patel, RM Hartley, X Wei, R Furnish, F Escobar-Riquelme, H Bear, ... Neuro-oncology 22 (3), 381-392, 2020 | 54 | 2020 |
Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy KB Haworth, MA Arnold, CR Pierson, K Choi, ND Yeager, N Ratner, ... Oncotarget 8 (47), 82037, 2017 | 54 | 2017 |
Pathobiological pseudohypoxia as a putative mechanism underlying myelodysplastic syndromes Y Hayashi, Y Zhang, A Yokota, X Yan, J Liu, K Choi, B Li, G Sashida, ... Cancer discovery 8 (11), 1438-1457, 2018 | 48 | 2018 |
An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system K Choi, K Komurov, JS Fletcher, E Jousma, JA Cancelas, J Wu, N Ratner Scientific Reports 7 (1), 43315, 2017 | 48 | 2017 |
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer N Oatman, N Dasgupta, P Arora, K Choi, MV Gawali, N Gupta, ... Science Advances 7 (7), eabd7459, 2021 | 47 | 2021 |
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST VW Keng, AL Watson, EP Rahrmann, H Li, BR Tschida, BS Moriarity, ... Sarcoma 2012 (1), 620834, 2012 | 47 | 2012 |