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Anai  M. Perez
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Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates
O Humbert, S Radtke, C Samuelson, RR Carrillo, AM Perez, SS Reddy, ...
Science translational medicine 11 (503), eaaw3768, 2019
1122019
Contact guidance diversity in rotationally aligned collagen matrices
JAM Nuhn, AM Perez, IC Schneider
Acta biomaterialia 66, 248-257, 2018
622018
Purification of human CD34+ CD90+ HSCs reduces target cell population and improves lentiviral transduction for gene therapy
S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ...
Molecular Therapy Methods & Clinical Development 18, 679-691, 2020
372020
Efficient polymer nanoparticle-mediated delivery of gene editing reagents into human hematopoietic stem and progenitor cells
R El-Kharrag, KE Berckmueller, R Madhu, M Cui, G Campoy, HM Mack, ...
Molecular Therapy 30 (6), 2186-2198, 2022
292022
Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering
KR Michels, A Sheih, SA Hernandez, AH Brandes, D Parrilla, B Irwin, ...
Journal for immunotherapy of cancer 11 (3), 2023
282023
Stochastic fate decisions of HSCs after transplantation: early contribution, symmetric expansion, and pool formation
S Radtke, M Enstrom, D Pande, ER Duke, EF Cardozo-Ojeda, R Madhu, ...
Blood, The Journal of the American Society of Hematology 142 (1), 33-43, 2023
82023
Preparation and gene modification of nonhuman primate hematopoietic stem and progenitor cells
S Radtke, AM Perez, R Venkataraman, S Reddy, KG Haworth, O Humbert, ...
JoVE (Journal of Visualized Experiments), e58933, 2019
72019
The rationale of using coffee and melatonin as an alternative treatment for alzheimer’s disease
A Perez, T Li, S Hernandez, R Zhang, C Cao
J Alzheimers Dis Parkinsonism 6 (205), 2161-0460.1000205, 2016
72016
Régimen de «visitas» del progenitor no custodio, su incidencia en la relación abuelosnietos
A Pérez
La protección del menor en las rupturas de pareja, 341-374, 2009
62009
Vivovec™ Surface-Engineered Lentiviral Particles Mediate In Vivo CAR T Generation with Potent and Highly Durable Activity in Non-Human Primates and Tumor-Bearing Humanized Mice
M Parker, J Ulrich-Lewis, W Tang, C Nicolai, K Michels, S Hernandez, ...
Blood 142, 765, 2023
42023
AMD3100 redosing fails to repeatedly mobilize hematopoietic stem cells in the nonhuman primate and humanized mouse
C Samuelson, S Radtke, M Cui, A Perez, HP Kiem, O Humbert
Experimental hematology 93, 52-60. e1, 2021
42021
Isolation of a highly purified HSC-enriched CD34+ CD90+ CD45RA− cell subset for allogeneic transplantation in the nonhuman primate large-animal model
S Radtke, L Colonna, AM Perez, M Hoffman, LS Kean, HP Kiem
Transplantation Direct 6 (8), e579, 2020
42020
Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction
S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ...
bioRxiv, 850479, 2019
42019
Efficient nanoparticle-mediated delivery of gene editing reagents into human hematopoietic stem and progenitor cells
R El Kharrag, K Berckmueller, M Cui, R Madhu, AM Perez, O Humbert, ...
Blood 138, 2933, 2021
22021
Hematopoietic recovery after transplantation is primarily derived from the stochastic contribution of hematopoietic stem cells
S Radtke, M Enstrom, D Pande, M Cui, R Madhu, AM Perez, HP Kiem
bioRxiv, 2021.09. 21.461235, 2021
12021
Transplantation and persistence of CRISPR/Cas9-edited hematopoietic stem and progenitors cells for the reactivation of fetal hemoglobin in nonhuman primates
O Humbert, S Radtke, RR Carrillo, SS Reddy, AM Perez, C Lux, ...
MOLECULAR THERAPY 26 (5), 296-296, 2018
12018
438 In vivo Engineered CAR-T cells for oncology using a surface-engineered lentivirus platform: nonclinical safety and biodistribution
A Brandes, SM Koo, D Parilla, S Hernandez, C Nicolai, A Sheih, A Ting, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
HSCs Engraft in a Stochastic Pattern and Form Clonal Pools after Transplantation
S Radtke, M Enstrom, D Pande, R Madhu, S Owen, G Kanestrom, M Cui, ...
Blood 140 (Supplement 1), 5719-5720, 2022
2022
Preclinical Activity and Safety of UB-VV100, A Novel Lentiviral Vector Product Designed for Selective and Effective In Vivo Engineering of Therapeutic Anti-CD19 CART Cells for …
AH Brandes, S Geisinger, A Sheih, A Ting, K Michels, SA Hernandez, ...
MOLECULAR THERAPY 30 (4), 579-580, 2022
2022
UB-VV100, a Novel Platform for In Vivo Engineering of Therapeutic Anti-CD19 CAR T Cells, Shows Effective T Cell Transduction, B Cell Depletion, and Tumor Control in a Humanized …
KR Michels, AM Sullivan, CJ Nicolai, SH Lopez, L Beitz, J Whalen, ...
MOLECULAR THERAPY 29 (4), 310-310, 2021
2021
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