Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 544 | 2019 |
Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility A Martin-Lorenzo, J Hauer, C Vicente-Duenas, F Auer, ... Cancer discovery 5 (12), 1328-1343, 2015 | 152 | 2015 |
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c. 547G> A F Auer, F Rüschendorf, M Gombert, P Husemann, S Ginzel, S Izraeli, ... Leukemia 28 (5), 1136-1138, 2014 | 104 | 2014 |
An intact gut microbiome protects genetically predisposed mice against leukemia C Vicente-Dueñas, S Janssen, M Oldenburg, F Auer, I González-Herrero, ... Blood, The Journal of the American Society of Hematology 136 (18), 2003-2017, 2020 | 96 | 2020 |
Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases G Rodríguez-Hernández, J Hauer, A Martín-Lorenzo, D Schäfer, ... Cancer Research 77 (16), 4365-4377, 2017 | 92 | 2017 |
STAT3 gain-of-function mutations associated with autoimmune lymphoproliferative syndrome like disease deregulate lymphocyte apoptosis and can be targeted by BH3 mimetic compounds S Nabhani, C Schipp, H Miskin, C Levin, S Postovsky, T Dujovny, A Koren, ... Clinical Immunology 181, 32-42, 2017 | 62 | 2017 |
Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL A Martín-Lorenzo, F Auer, LN Chan, I García-Ramírez, I Gonzalez-Herrero, ... Cancer research 78 (10), 2669-2679, 2018 | 49 | 2018 |
Regional BCG vaccination policy in former East-and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia J Hauer, U Fischer, F Auer, A Borkhardt Leukemia 34 (8), 2217-2219, 2020 | 32 | 2020 |
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID G Rodríguez-Hernández, FV Opitz, P Delgado, C Walter, ... Nature Communications 10 (1), 5563, 2019 | 32 | 2019 |
Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy C Vicente-Duenas, J Hauer, L Ruiz-Roca, D Ingenhag, ... Seminars in cancer biology 32, 3-9, 2015 | 30 | 2015 |
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The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells D Ingenhag, S Reister, F Auer, S Bhatia, S Wildenhain, D Picard, ... haematologica 104 (1), 35, 2019 | 20 | 2019 |
Temperature- and nitrogen source-dependent regulation of GlnR target genes in Listeria monocytogenes D Kaspar, F Auer, J Schardt, F Schindele, A Ospina, C Held, A Ehrenreich, ... FEMS Microbiology Letters 355 (2), 131-141, 2014 | 15 | 2014 |
JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility M Lin, K Nebral, CGW Gertzen, I Ganmore, OA Haas, S Bhatia, U Fischer, ... Leukemia 33 (9), 2331-2335, 2019 | 11 | 2019 |
Germline POT1 deregulation can predispose to myeloid malignancies in childhood P Michler, A Schedel, M Witschas, UA Friedrich, R Wagener, J Mehtonen, ... International Journal of Molecular Sciences 22 (21), 11572, 2021 | 10 | 2021 |
Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants A Escudero, M Takagi, F Auer, UA Friedrich, S Miyamoto, A Ogawa, ... Leukemia 36 (9), 2338-2342, 2022 | 8 | 2022 |
Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells F Auer, D Ingenhag, S Pinkert, S Kracker, S Hacein-Bey-Abina, ... Oncotarget 8 (44), 75797, 2017 | 8 | 2017 |
The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients R Wagener, C Walter, F Auer, D Alzoubi, J Hauer, U Fischer, J Varghese, ... International Journal of Cancer 152 (7), 1388-1398, 2023 | 7 | 2023 |
A rare PALB2 germline variant causing G2/M cell cycle arrest is associated with isolated myelosarcoma in infancy A Beer, R Beck, A Schedel, M von Bonin, J Meinel, UA Friedrich, ... Molecular genetics & genomic medicine 9 (9), e1746, 2021 | 6 | 2021 |
Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies C Saitta, S Rebellato, LR Bettini, G Giudici, N Panini, E Erba, V Massa, ... Blood Cancer Journal 12 (6), 88, 2022 | 5 | 2022 |