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Nicolas Giguère
Nicolas Giguère
PhD
在 umontreal.ca 的电子邮件经过验证
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引用次数
引用次数
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Elevated mitochondrial bioenergetics and axonal arborization size are key contributors to the vulnerability of dopamine neurons
C Pacelli, N Giguère, MJ Bourque, M Lévesque, RS Slack, LÉ Trudeau
Current Biology 25 (18), 2349-2360, 2015
4932015
On cell loss and selective vulnerability of neuronal populations in Parkinson's disease
N Giguère, S Burke Nanni, LE Trudeau
Frontiers in neurology 9, 455, 2018
3992018
Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons
H Doucet-Beaupré, C Gilbert, MS Profes, A Chabrat, C Pacelli, N Giguère, ...
Proceedings of the National Academy of Sciences 113 (30), E4387-E4396, 2016
842016
Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout
N Giguère, B Delignat-Lavaud, F Herborg, A Voisin, Y Li, V Jacquemet, ...
PLoS genetics 15 (8), e1008352, 2019
762019
Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism
JA Gleave, LR Arathoon, D Trinh, KE Lizal, N Giguere, JHM Barber, ...
Neurobiology of disease 106, 133-146, 2017
622017
Comparative analysis of Parkinson's disease–associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons
N Giguère, C Pacelli, C Saumure, MJ Bourque, D Matheoud, D Levesque, ...
Journal of Biological Chemistry 293 (25), 9580-9593, 2018
382018
Segregation of dopamine and glutamate release sites in dopamine neuron axons: regulation by striatal target cells
GM Fortin, C Ducrot, N Giguere, WM Kouwenhoven, MJ Bourque, ...
The FASEB Journal 33 (1), 400-417, 2019
372019
Axonal segregation and role of the vesicular glutamate transporter VGLUT3 in serotonin neurons
AN Voisin, O Mnie-Filali, N Giguère, GM Fortin, E Vigneault, ...
Frontiers in neuroanatomy 10, 39, 2016
272016
Oleic acid in the ventral tegmental area inhibits feeding, food reward, and dopamine tone
C Hryhorczuk, Z Sheng, L Décarie-Spain, N Giguère, C Ducrot, ...
Neuropsychopharmacology 43 (3), 607-616, 2018
262018
Neonatal 6‐OHDA lesion of the SNc induces striatal compensatory sprouting from surviving SNc dopaminergic neurons without VTA contribution
W Tanguay, C Ducrot, N Giguère, MJ Bourque, LE Trudeau
European Journal of Neuroscience 54 (7), 6618-6632, 2021
122021
The calcium sensor synaptotagmin-1 is critical for phasic axonal dopamine release in the striatum and mesencephalon, but is dispensable for basic motor behaviors in mice
B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ...
bioRxiv, 2021
122021
Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor
D Thibault, N Giguère, F Loustalot, MJ Bourque, C Ducrot, S El Mestikawy, ...
Brain Structure and Function 221, 2093-2107, 2016
92016
Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ...
Nature Communications 14 (1), 4120, 2023
62023
Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons
C Ducrot, G de Carvalho, B Delignat-Lavaud, CVL Delmas, P Halder, ...
Elife 12, e87902, 2023
42023
Neurexins regulate GABA co-release by dopamine neurons
C Ducrot, G de Carvalho, B Delignat-Lavaud, CVL Delmas, N Giguère, ...
bioRxiv, 2021.10. 17.464666, 2021
42021
Axon arborization size is a key factor influencing cellular bioenergetics and vulnerability of dopamine neurons in Parkinson's disease
N Giguère, LÉ Trudeau
Medecine sciences: M/S 32 (4), 342-344, 2016
22016
DAB Immunohistochemistry (IHC) Staining for Stereological Analysis
N Giguère
2024
Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system
MN Elemeery, A Tchung, S Boulet, S Mukherjee, N Giguere, JF Daudelin, ...
bioRxiv, 2024.02. 26.582098, 2024
2024
Protocols for" Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice"
B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ...
2023
Primary Culture of Mouse Mesencephalic Neurons V. 2
N Giguère
2020
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