Elevated mitochondrial bioenergetics and axonal arborization size are key contributors to the vulnerability of dopamine neurons C Pacelli, N Giguère, MJ Bourque, M Lévesque, RS Slack, LÉ Trudeau Current Biology 25 (18), 2349-2360, 2015 | 493 | 2015 |
On cell loss and selective vulnerability of neuronal populations in Parkinson's disease N Giguère, S Burke Nanni, LE Trudeau Frontiers in neurology 9, 455, 2018 | 399 | 2018 |
Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons H Doucet-Beaupré, C Gilbert, MS Profes, A Chabrat, C Pacelli, N Giguère, ... Proceedings of the National Academy of Sciences 113 (30), E4387-E4396, 2016 | 84 | 2016 |
Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout N Giguère, B Delignat-Lavaud, F Herborg, A Voisin, Y Li, V Jacquemet, ... PLoS genetics 15 (8), e1008352, 2019 | 76 | 2019 |
Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism JA Gleave, LR Arathoon, D Trinh, KE Lizal, N Giguere, JHM Barber, ... Neurobiology of disease 106, 133-146, 2017 | 62 | 2017 |
Comparative analysis of Parkinson's disease–associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons N Giguère, C Pacelli, C Saumure, MJ Bourque, D Matheoud, D Levesque, ... Journal of Biological Chemistry 293 (25), 9580-9593, 2018 | 38 | 2018 |
Segregation of dopamine and glutamate release sites in dopamine neuron axons: regulation by striatal target cells GM Fortin, C Ducrot, N Giguere, WM Kouwenhoven, MJ Bourque, ... The FASEB Journal 33 (1), 400-417, 2019 | 37 | 2019 |
Axonal segregation and role of the vesicular glutamate transporter VGLUT3 in serotonin neurons AN Voisin, O Mnie-Filali, N Giguère, GM Fortin, E Vigneault, ... Frontiers in neuroanatomy 10, 39, 2016 | 27 | 2016 |
Oleic acid in the ventral tegmental area inhibits feeding, food reward, and dopamine tone C Hryhorczuk, Z Sheng, L Décarie-Spain, N Giguère, C Ducrot, ... Neuropsychopharmacology 43 (3), 607-616, 2018 | 26 | 2018 |
Neonatal 6‐OHDA lesion of the SNc induces striatal compensatory sprouting from surviving SNc dopaminergic neurons without VTA contribution W Tanguay, C Ducrot, N Giguère, MJ Bourque, LE Trudeau European Journal of Neuroscience 54 (7), 6618-6632, 2021 | 12 | 2021 |
The calcium sensor synaptotagmin-1 is critical for phasic axonal dopamine release in the striatum and mesencephalon, but is dispensable for basic motor behaviors in mice B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ... bioRxiv, 2021 | 12 | 2021 |
Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor D Thibault, N Giguère, F Loustalot, MJ Bourque, C Ducrot, S El Mestikawy, ... Brain Structure and Function 221, 2093-2107, 2016 | 9 | 2016 |
Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ... Nature Communications 14 (1), 4120, 2023 | 6 | 2023 |
Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons C Ducrot, G de Carvalho, B Delignat-Lavaud, CVL Delmas, P Halder, ... Elife 12, e87902, 2023 | 4 | 2023 |
Neurexins regulate GABA co-release by dopamine neurons C Ducrot, G de Carvalho, B Delignat-Lavaud, CVL Delmas, N Giguère, ... bioRxiv, 2021.10. 17.464666, 2021 | 4 | 2021 |
Axon arborization size is a key factor influencing cellular bioenergetics and vulnerability of dopamine neurons in Parkinson's disease N Giguère, LÉ Trudeau Medecine sciences: M/S 32 (4), 342-344, 2016 | 2 | 2016 |
DAB Immunohistochemistry (IHC) Staining for Stereological Analysis N Giguère | | 2024 |
Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system MN Elemeery, A Tchung, S Boulet, S Mukherjee, N Giguere, JF Daudelin, ... bioRxiv, 2024.02. 26.582098, 2024 | | 2024 |
Protocols for" Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice" B Delignat-Lavaud, J Kano, C Ducrot, I Massé, S Mukherjee, N Giguère, ... | | 2023 |
Primary Culture of Mouse Mesencephalic Neurons V. 2 N Giguère | | 2020 |