Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology FE McAlpine, JK Lee, AS Harms, KA Ruhn, M Blurton-Jones, J Hong, ... Neurobiology of disease 34 (1), 163-177, 2009 | 303 | 2009 |
The concise guide to pharmacology 2021/22: Introduction and other protein targets SPH Alexander, E Kelly, A Mathie, JA Peters, EL Veale, JF Armstrong, ... British journal of pharmacology 178, S1-S26, 2021 | 237 | 2021 |
Neuroinflammation in Parkinson’s disease JK Lee, T Tran, MG Tansey Journal of Neuroimmune Pharmacology 4, 419-429, 2009 | 205 | 2009 |
Microglia isolation from adult mouse brain JK Lee, MG Tansey Microglia: Methods and Protocols, 17-23, 2013 | 147 | 2013 |
Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy MG Tansey, TC Frank-Cannon, MK McCoy, JK Lee, TN Martinez, ... Front Biosci 13 (5), 709-717, 2008 | 145 | 2008 |
Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control study GT Kannarkat, C DA, JK Lee, J Chang, J Chung, E Sandy, EM Sperin, ... NPJ Parkinson's disease 1 (1), 1-9, 2015 | 127 | 2015 |
Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic mice RH Earls, KB Menees, J Chung, J Barber, CA Gutekunst, MG Hazim, ... Journal of Neuroinflammation 16 (1), 1-15, 2019 | 124 | 2019 |
Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B TA Tran, AD Nguyen, J Chang, MS Goldberg, JK Lee, MG Tansey PloS one 6 (8), e23660, 2011 | 124 | 2011 |
Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells SV Vaidya, SE Stepp, ME McNerney, JK Lee, M Bennett, KM Lee, ... The Journal of Immunology 174 (2), 800-807, 2005 | 122 | 2005 |
NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy. RH Earls, KB Menees, J Chung, CA Gutekunst, HJ Lee, MG Hazim, ... Proceedings of the National Academy of Sciences of the United States of …, 2020 | 105 | 2020 |
Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response JK Lee, MK McCoy, AS Harms, KA Ruhn, SJ Gold, MG Tansey Journal of Neuroscience 28 (34), 8517-8528, 2008 | 103 | 2008 |
CS1 (CRACC, CD319) induces proliferation and autocrine cytokine expression on human B lymphocytes JK Lee, SO Mathew, SV Vaidya, PR Kumaresan, PA Mathew The Journal of Immunology 179 (7), 4672-4678, 2007 | 93 | 2007 |
Regulator of G-protein Signaling-10 negatively regulates NF-κB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats JK Lee, J Chung, FE McAlpine, MG Tansey The Journal of Neuroscience 31 (33), 11879-11888, 2011 | 77 | 2011 |
Recombinant tissue plasminogen activator promotes, and progesterone attenuates, microglia/macrophage M1 polarization and recruitment of microglia after MCAO stroke in rats S Won, JK Lee, DG Stein Brain, behavior, and immunity 49, 267-279, 2015 | 76 | 2015 |
Regulation of microglia effector functions by tumor necrosis factor signaling AS Harms, JK Lee, TA Nguyen, J Chang, KM Ruhn, I Treviño, MG Tansey Glia 60 (2), 189-202, 2012 | 66 | 2012 |
The role of natural killer cells in Parkinson’s disease RH Earls, JK Lee Experimental Molecular Medicine, 2020 | 57 | 2020 |
C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Q Shao, M Yang, C Liang, L Ma, W Zhang, JK Lee, C Liang, JF Chen Autophage, 2019 | 54 | 2019 |
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine‐based switch motifs JK Lee, KS Boles, PA Mathew European journal of immunology 34 (10), 2791-2799, 2004 | 54 | 2004 |
Sex-and age‐dependent alterations of splenic immune cell profile and NK cell phenotypes and function in C57BL/6J mice KB Menees, RH Earls, J Chung, J Jernigan, NM Filipov, JM Carpenter, ... Immunity & Ageing 18, 1-13, 2021 | 51 | 2021 |
Protein kinase C is involved in 2B4 (CD244)‐mediated cytotoxicity and AP‐1 activation in natural killer cells SS Chuang, JK Lee, PA Mathew Immunology 109 (3), 432-439, 2003 | 43 | 2003 |