Nanomedicine: application areas and development prospects H Boulaiz, PJ Alvarez, A Ramirez, JA Marchal, J Prados, ... International journal of molecular sciences 12 (5), 3303-3321, 2011 | 255 | 2011 |
Activating transcription factor 4 modulates TGFβ-induced aggressiveness in triple-negative breast cancer via SMAD2/3/4 and mTORC2 signaling A González-González, E Muñoz-Muela, JA Marchal, FE Cara, MP Molina, ... Clinical Cancer Research 24 (22), 5697-5709, 2018 | 60 | 2018 |
5-Fluorouracil derivatives: a patent review (2012–2014) E Carrillo, SA Navarro, A Ramírez, MÁ García, C Griñán-Lisón, M Perán, ... Expert opinion on therapeutic patents 25 (10), 1131-1144, 2015 | 55 | 2015 |
New (RS)-benzoxazepin-purines with antitumour activity: the chiral switch from (RS)-2, 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1, 2, 3, 5-tetrahydro-4, 1-benzoxazepin-3-yl]-9H … LC López-Cara, A Conejo-García, JA Marchal, G Macchione, ... European journal of medicinal chemistry 46 (1), 249-258, 2011 | 54 | 2011 |
Synthesis and anticancer activity of (RS)-9-(2, 3-dihydro-1, 4-benzoxaheteroin-2-ylmethyl)-9H-purines A Conejo-García, ME García-Rubiño, JA Marchal, MC Núñez, A Ramirez, ... European journal of medicinal chemistry 46 (9), 3795-3801, 2011 | 51 | 2011 |
Mesenchymal stem cell's secretome promotes selective enrichment of cancer stem-like cells with specific cytogenetic profile G Jiménez, M Hackenberg, P Catalina, H Boulaiz, C Griñán-Lisón, ... Cancer Letters 429, 78-88, 2018 | 39 | 2018 |
HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib A Ramírez, H Boulaiz, C Morata-Tarifa, M Perán, G Jiménez, ... Oncotarget 5 (11), 3590, 2014 | 32 | 2014 |
Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence JA Marchal, E Carrasco, A Ramirez, G Jiménez, C Olmedo, M Peran, ... Drug Design, Development and Therapy, 1301-1313, 2013 | 31 | 2013 |
Albumin-covered lipid nanocapsules exhibit enhanced uptake performance by breast-tumor cells F Galisteo-González, JA Molina-Bolívar, SA Navarro, H Boulaiz, ... Colloids and Surfaces B: Biointerfaces 165, 103-110, 2018 | 29 | 2018 |
Anti-proliferative activity of 2, 6-dichloro-9-or 7-(ethoxycarbonylmethyl)-9H-or 7H-purines against several human solid tumour cell lines F Morales, A Ramirez, A Conejo-Garcia, C Morata, JA Marchal, ... European Journal of Medicinal Chemistry 76, 118-124, 2014 | 29 | 2014 |
Apoptosis as a therapeutic target in cancer and cancer stem cells: novel strategies and futures perspectives MA García, E Carrasco, A Ramírez, G Jiménez, E López-Ruiz, M Perán, ... Apoptosis and medicine, 2012 | 21 | 2012 |
Deciphering the mechanism of action involved in enhanced suicide gene colon cancer cell killer effect mediated by gef and apoptin B Cáceres, A Ramirez, E Carrillo, G Jimenez, C Griñán-Lisón, ... Cancers 11 (2), 264, 2019 | 20 | 2019 |
Enhancement of Tumor Cell Death by Combining gef Gene Mediated Therapy and New 1,4-Benzoxazepin-2,6-Dichloropurine Derivatives in Breast Cancer Cells A Ramírez, A Conejo-García, C Griñán-Lisón, LC López-Cara, G Jiménez, ... Frontiers in Pharmacology 9, 798, 2018 | 11 | 2018 |
Antitumoral activity of 1, 2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells F Morales, A Ramírez, C Morata-Tarifa, SA Navarro, JA Marchal, ... Future Medicinal Chemistry 9 (3), 293-302, 2017 | 10 | 2017 |
gef Gene Expression in MCF-7 Breast Cancer Cells is Associated with a Better Prognosis and Induction of Apoptosis by p53-Mediated Signaling Pathway H Boulaiz, PJ Álvarez, J Prados, J Marchal, C Melguizo, E Carrillo, ... International Journal of Molecular Sciences 12 (11), 7445-7458, 2011 | 10 | 2011 |
Synthesis and Anticancer Activity of the (R,S)‐Benzofused 1,5‐Oxathiepine Moiety Tethered to Purines through Alkylidenoxy Linkers M Kimatrai, A Conejo‐García, A Ramírez, E Andreolli, ... ChemMedChem 6 (10), 1854-1859, 2011 | 9 | 2011 |
1-(Benzenesulfonyl)-1, 5-dihydro-4, 1-benzoxazepine as a new scaffold for the design of antitumor compounds O Cruz-López, A Ramírez, SA Navarro, MA García, JA Marchal, ... Future Medicinal Chemistry 9 (11), 1129-1140, 2017 | 3 | 2017 |
p-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl) anilines as novel antitumour agents F Morales, A Conejo-García, A Ramírez, C Morata, JA Marchal, ... RSC advances 5 (93), 76615-76619, 2015 | 2 | 2015 |
Evaluación Educativa A Ramírez, JPC Campos, MCJM Rodríguez, S Académica Recuperado el 20, 2005 | 2 | 2005 |
Knockdown of TGFβ-activated ATF4 inhibits triple negative breast cancer metastases independently of cellular stress JC Chang, A Ramirez, MP Molina, FE Cara, W Qian, W Chen, ... Cancer Research 78 (13_Supplement), 2035-2035, 2018 | 1 | 2018 |