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Qinghui Wang
Qinghui Wang
University of Tennessee Health Science Center, Memorial Sloan Kettering Cancer Center
在 mskcc.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues …
Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, SW White, DD Miller, W Li, ...
Journal of Medicinal Chemistry 62 (14), 6734-6750, 2019
732019
Recent advances in heterocyclic tubulin inhibitors targeting the colchicine binding site
X Wu, Q Wang, W Li
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2016
642016
Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
HW Humayun Sharif, L. Robert Hollingsworth, Andrew R. Griswold, Jeffrey C ...
immunity 54, 1–13, 2021
58*2021
Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells
G Zhao, Q Wang, Q Gu, W Qiang, JJ Wei, P Dong, H Watari, W Li, J Yue
Oncotarget 8 (55), 94666, 2017
502017
Structural modification of the 3, 4, 5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities
Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, H Chen, Z Wu, J Yang, ...
Journal of medicinal chemistry 61 (17), 7877-7891, 2018
472018
A new oxyma derivative for nonracemizable amide-forming reactions in water
Q Wang, Y Wang, M Kurosu
Organic letters 14 (13), 3372-3375, 2012
472012
Selective esterifications of primary alcohols in a water-containing solvent
Y Wang, BA Aleiwi, Q Wang, M Kurosu
Organic letters 14 (18), 4910-4913, 2012
422012
Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer
VK Kashyap, Q Wang, S Setua, PKB Nagesh, N Chauhan, S Kumari, ...
Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019
342019
Ovarian primary and metastatic tumors suppressed by survivin knockout or a novel survivin inhibitor
G Zhao, Q Wang, Z Wu, X Tian, H Yan, B Wang, P Dong, H Watari, ...
Molecular cancer therapeutics 18 (12), 2233-2245, 2019
322019
An orally available tubulin inhibitor, VERU-111, suppresses triple-negative breast cancer tumor growth and metastasis and bypasses taxane resistance
S Deng, RI Krutilina, Q Wang, Z Lin, DN Parke, HC Playa, H Chen, ...
Molecular cancer therapeutics 19 (2), 348-363, 2020
312020
The NLRP1 and CARD8 inflammasomes detect reductive stress
Q Wang, JC Hsiao, N Yardeny, HC Huang, CM O’Mara, EL Orth-He, ...
Cell reports 42 (1), 2023
302023
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome
DAB Sahana D. Rao#, Qifeng Chen#, Qinghui Wang#, Elizabeth L. Orth-He ...
Nature Chemical biology, 2022
282022
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome
DAB Daniel P Ball, Alvin E. Wang, Charles D. Warren, Qinghui Wang, Andrew R ...
BioRxiv, 2021
27*2021
Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors
Q Wang, KE Arnst, Y Xue, ZN Lei, D Ma, ZS Chen, DD Miller, W Li
European journal of medicinal chemistry 149, 211-224, 2018
212018
Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
EL Orth-He, HC Huang, SD Rao, Q Wang, Q Chen, CM O’Mara, AJ Chui, ...
Cell reports 42 (1), 2023
202023
Flavonoids isolated from Sinopodophylli Fructus and their bioactivities against human breast cancer cells
W Qing-Hui, GUO Shuai, Y Xue-Yan, YF Zhang, MY Shang, YH Shang, ...
Chinese journal of natural medicines 15 (3), 225-233, 2017
202017
VERU-111 suppresses tumor growth and metastatic phenotypes of cervical cancer cells through the activation of p53 signaling pathway
VK Kashyap, N Dan, N Chauhan, Q Wang, S Setua, PKB Nagesh, S Malik, ...
Cancer letters 470, 64-74, 2020
152020
A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome
JC Hsiao, AR Neugroschl, AJ Chui, CY Taabazuing, AR Griswold, ...
Journal of Biological Chemistry 298 (7), 2022
142022
Total synthesis of biologically active 20S-hydroxyvitamin D3
Q Wang, Z Lin, TK Kim, AT Slominski, DD Miller, W Li
Steroids 104, 153-162, 2015
142015
Triple-Isotope Tracing for Pathway Discernment of NMN-Induced NAD+ Biosynthesis in Whole Mice
AA Sauve, Q Wang, N Zhang, S Kang, A Rathmann, Y Yang
International Journal of Molecular Sciences 24 (13), 11114, 2023
82023
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