Activation of RhoA by thrombin in endothelial hyperpermeability: role of Rho kinase and protein tyrosine kinases GPN Amerongen, S Delft, MA Vermeer, JG Collard, VWM van Hinsbergh Circulation research 87 (4), 335-340, 2000 | 511 | 2000 |
Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro GP van Nieuw Amerongen, P Koolwijk, A Versteilen, VWM van Hinsbergh Arteriosclerosis, thrombosis, and vascular biology 23 (2), 211-217, 2003 | 409 | 2003 |
Transient and Prolonged Increase in Endothelial Permeability Induced by Histamine and Thrombin: Role of Protein Kinases, Calcium, and RhoA GPN Amerongen, R Draijer, MA Vermeer, VWM van Hinsbergh Circulation research 83 (11), 1115-1123, 1998 | 342 | 1998 |
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. MJ Smit, R Leurs, AE Alewijnse, J Blauw, GP van Nieuw Amerongen, ... Proceedings of the National Academy of Sciences 93 (13), 6802-6807, 1996 | 280 | 1996 |
Electric cell-substrate impedance sensing for the quantification of endothelial proliferation, barrier function, and motility R Szulcek, HJ Bogaard, GP van Nieuw Amerongen JoVE (Journal of Visualized Experiments), e51300, 2014 | 279 | 2014 |
Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces R Krishnan, DD Klumpers, CY Park, K Rajendran, X Trepat, J Van Bezu, ... American Journal of Physiology-Cell Physiology 300 (1), C146-C154, 2011 | 265 | 2011 |
Driving Rho GTPase activity in endothelial cells regulates barrier integrity CML Beckers, VWM van Hinsbergh, GP van Nieuw Amerongen Thrombosis and haemostasis 103 (01), 40-55, 2010 | 249 | 2010 |
Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients M van der Heijden, GP van Nieuw Amerongen, P Koolwijk, ... Thorax 63 (10), 903-909, 2008 | 247 | 2008 |
Role of RhoA and Rho kinase in lysophosphatidic acid–induced endothelial barrier dysfunction GPN Amerongen, MA Vermeer, VWM van Hinsbergh Arteriosclerosis, thrombosis, and vascular biology 20 (12), e127-e133, 2000 | 221 | 2000 |
Simvastatin improves disturbed endothelial barrier function GPN Amerongen, MA Vermeer, P Nègre-Aminou, J Lankelma, JJ Emeis, ... Circulation 102 (23), 2803-2809, 2000 | 217 | 2000 |
Plasma biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis ML Terpstra, J Aman, GP van Nieuw Amerongen, ABJ Groeneveld Critical care medicine 42 (3), 691-700, 2014 | 211 | 2014 |
Involvement of Rho kinase in endothelial barrier maintenance GP van Nieuw Amerongen, CML Beckers, ID Achekar, S Zeeman, ... Arteriosclerosis, thrombosis, and vascular biology 27 (11), 2332-2339, 2007 | 208 | 2007 |
Cytoskeletal effects of Rho-like small guanine nucleotide–binding proteins in the vascular system GP van Nieuw Amerongen, VWM van Hinsbergh Arteriosclerosis, thrombosis, and vascular biology 21 (3), 300-311, 2001 | 207 | 2001 |
Targets for pharmacological intervention of endothelial hyperpermeability and barrier function GP van Nieuw Amerongen, VWM van Hinsbergh Vascular pharmacology 39 (4-5), 257-272, 2002 | 194 | 2002 |
Crystalloid or colloid fluid loading and pulmonary permeability, edema, and injury in septic and nonseptic critically ill patients with hypovolemia M Van Der Heijden, J Verheij, GP van Nieuw Amerongen, ... Critical care medicine 37 (4), 1275-1281, 2009 | 193 | 2009 |
Intracellular signalling involved in modulating human endothelial barrier function VWM Van Hinsbergh, GP van Nieuw Amerongen Journal of anatomy 200 (5), 523-534, 2002 | 191 | 2002 |
Effective treatment of edema and endothelial barrier dysfunction with imatinib J Aman, J van Bezu, A Damanafshan, S Huveneers, EC Eringa, SM Vogel, ... Circulation 126 (23), 2728-2738, 2012 | 184 | 2012 |
Vasoconstrictor effects of insulin in skeletal muscle arterioles are mediated by ERK1/2 activation in endothelium EC Eringa, CDA Stehouwer, GP van Nieuw Amerongen, L Ouwehand, ... American Journal of Physiology-Heart and Circulatory Physiology 287 (5 …, 2004 | 157 | 2004 |
Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition Z Chen, FR Bakhshi, AN Shajahan, T Sharma, M Mao, A Trane, ... Molecular biology of the cell 23 (7), 1388-1398, 2012 | 152 | 2012 |
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium RA Boon, TA Leyen, RD Fontijn, JO Fledderus, JMC Baggen, OL Volger, ... Blood, The Journal of the American Society of Hematology 115 (12), 2533-2542, 2010 | 141 | 2010 |