Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis Q Zhou, S Haupt, JT Kreuzer, A Hammitzsch, F Proft, C Neumann, J Leipe, ... Annals of the rheumatic diseases 74 (6), 1265-1274, 2015 | 213 | 2015 |
RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment E Benito, C Kerimoglu, B Ramachandran, T Pena-Centeno, G Jain, ... Cell Reports 23 (2), 546-554, 2018 | 149 | 2018 |
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss MH Schludi, L Becker, L Garrett, TF Gendron, Q Zhou, F Schreiber, ... Acta neuropathologica 134, 241-254, 2017 | 132 | 2017 |
Antibodies inhibit transmission and aggregation of C9orf72 poly‐GA dipeptide repeat proteins Q Zhou, C Lehmer, M Michaelsen, K Mori, D Alterauge, D Baumjohann, ... EMBO molecular medicine 9 (5), 687-702, 2017 | 96 | 2017 |
miR-142-3p is involved in CD25+ CD4 T cell proliferation by targeting the expression of glycoprotein A repetitions predominant Q Zhou, S Haupt, I Prots, K Thümmler, E Kremmer, PE Lipsky, ... The Journal of Immunology 190 (12), 6579-6588, 2013 | 72 | 2013 |
Cell‐to‐cell transmission of C9orf72 poly‐(Gly‐Ala) triggers key features of ALS/FTD B Khosravi, KD LaClair, H Riemenschneider, Q Zhou, F Frottin, N Mareljic, ... The EMBO journal 39 (8), e102811, 2020 | 71 | 2020 |
Active poly‐GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model Q Zhou, N Mareljic, M Michaelsen, S Parhizkar, S Heindl, B Nuscher, ... EMBO molecular medicine 12 (2), e10919, 2020 | 61 | 2020 |
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS KD LaClair, Q Zhou, M Michaelsen, B Wefers, MS Brill, A Janjic, ... Acta neuropathologica 140, 121-142, 2020 | 60 | 2020 |
Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3 Y Nihei, K Mori, G Werner, T Arzberger, Q Zhou, B Khosravi, J Japtok, ... Acta neuropathologica 139, 99-118, 2020 | 57 | 2020 |
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide‐repeat protein deposition K Mori, Y Nihei, T Arzberger, Q Zhou, IR Mackenzie, A Hermann, ... EMBO reports 17 (9), 1314-1325, 2016 | 42 | 2016 |
Clinico-genetic findings in 509 frontotemporal dementia patients M Wagner, G Lorenz, AE Volk, T Brunet, D Edbauer, R Berutti, C Zhao, ... Molecular psychiatry 26 (10), 5824-5832, 2021 | 36 | 2021 |
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies S Heindl, A Ricci, O Carofiglio, Q Zhou, T Arzberger, N Lenart, ... Journal of Experimental Medicine 218 (8), e20202411, 2021 | 34 | 2021 |
German Consortium for Frontotemporal Lobar Degeneration; Bavarian Brain Banking Alliance, Kamp F, Nuscher B, Orozco D, Edbauer D, Haass C (2016) Reduced hnRNPA3 increases … K Mori, Y Nihei, T Arzberger, Q Zhou, IR Mackenzie, A Hermann, ... EMBO Rep 17, 1314-1325, 0 | 17 | |
Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2) n expression in C9orf72 ALS/FTD M Czuppa, A Dhingra, Q Zhou, C Schludi, L König, E Scharf, D Farny, ... Cell reports 39 (10), 2022 | 14 | 2022 |
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo H Riemenschneider, F Simonetti, U Sheth, E Katona, S Roth, S Hutten, ... Acta Neuropathologica Communications 11 (1), 112, 2023 | 9 | 2023 |
German Consortium for Frontotemporal Lobar Degeneration Y Nihei, K Mori, G Werner, T Arzberger, Q Zhou, B Khosravi, J Japtok, ... Mori, K, 99-118, 2020 | 7 | 2020 |
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. EMBO Mol Med 9: 687–702 Q Zhou, C Lehmer, M Michaelsen, K Mori, D Alterauge, D Baumjohann, ... | 6 | 2017 |
Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target LC Gomes, S Hänzelmann, S Oller, M Parvaz, F Hausmann, R Khatri, ... | 2 | 2023 |
Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target L Caldi Gomes, S Hänzelmann, F Hausmann, R Khatri, S Oller, M Parvaz, ... bioRxiv, 2023.08. 14.553180, 2023 | 1 | 2023 |
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target L Caldi Gomes, S Hänzelmann, F Hausmann, R Khatri, S Oller, M Parvaz, ... Nature Communications 15 (1), 4893, 2024 | | 2024 |