| The ins and outs of MHC class II-mediated antigen processing and presentation PA Roche, K Furuta Nature Reviews Immunology 15 (4), 203-216, 2015 | 1183 | 2015 |
| Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding PA Roche, P Cresswell Nature 345 (6276), 615-618, 1990 | 678 | 1990 |
| Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain PA Roche, MS Marks, PJ Cresswell Nature 354 (6352), 392-394, 1991 | 446 | 1991 |
| Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation HA Anderson, EM Hiltbold, PA Roche Nature immunology 1 (2), 156-162, 2000 | 400 | 2000 |
| Identification of a novel syntaxin-and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues V Ravichandran, A Chawla, PA Roche Journal of Biological Chemistry 271 (23), 13300-13303, 1996 | 398 | 1996 |
| Defective cytotoxic lymphocyte degranulation in syntaxin-11–deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients YT Bryceson, E Rudd, C Zheng, J Edner, D Ma, SM Wood, ... Blood, The Journal of the American Society of Hematology 110 (6), 1906-1915, 2007 | 375 | 2007 |
| TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation P Nair-Gupta, A Baccarini, N Tung, F Seyffer, O Florey, Y Huang, ... Cell 158 (3), 506-521, 2014 | 354 | 2014 |
| T cell‐induced secretion of MHC class II–peptide complexes on B cell exosomes A Muntasell, AC Berger, PA Roche The EMBO journal 26 (19), 4263-4272, 2007 | 332 | 2007 |
| Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. PA Roche, P Cresswell Proceedings of the National Academy of Sciences 88 (8), 3150-3154, 1991 | 313 | 1991 |
| Suppression of antigen presentation by IL-10 SK Mittal, PA Roche Current opinion in immunology 34, 22-27, 2015 | 301 | 2015 |
| Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization. PA Roche, CL Teletski, E Stang, O Bakke, EO Long Proceedings of the National Academy of Sciences 90 (18), 8581-8585, 1993 | 298 | 1993 |
| Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms N Puri, PA Roche Proceedings of the national academy of sciences 105 (7), 2580-2585, 2008 | 266 | 2008 |
| A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments. MS Marks, PA Roche, E van Donselaar, L Woodruff, PJ Peters, ... The Journal of cell biology 131 (2), 351-369, 1995 | 234 | 1995 |
| Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis HF Langer, KJ Chung, VV Orlova, EY Choi, S Kaul, MJ Kruhlak, ... Blood, The Journal of the American Society of Hematology 116 (22), 4395-4403, 2010 | 200 | 2010 |
| HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes JD Weissman, JA Brown, TK Howcroft, J Hwang, A Chawla, PA Roche, ... Proceedings of the National Academy of Sciences 95 (20), 11601-11606, 1998 | 199 | 1998 |
| High-affinity binding of an influenza hemagglutinin-derived peptide to purified HLA-DR. PA Roche, P Cresswell Journal of Immunology (Baltimore, Md.: 1950) 144 (5), 1849-1856, 1990 | 197 | 1990 |
| Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells Z Liu, PA Roche Frontiers in physiology 6, 1, 2015 | 186 | 2015 |
| Trafficking of MHC class II molecules in the late secretory pathway EM Hiltbold, PA Roche Current opinion in immunology 14 (1), 30-35, 2002 | 173 | 2002 |
| MHC class II-peptide complexes and APC lipid rafts accumulate at the immunological synapse EM Hiltbold, NJ Poloso, PA Roche The Journal of Immunology 170 (3), 1329-1338, 2003 | 167 | 2003 |
| Major histocompatibility complex class II-peptide complexes internalize using a clathrin-and dynamin-independent endocytosis pathway E Walseng, O Bakke, PA Roche Journal of Biological Chemistry 283 (21), 14717-14727, 2008 | 166 | 2008 |
