| The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis LI Xin, DA Lawson, ON Witte Proceedings of the National Academy of Sciences 102 (19), 6942-6947, 2005 | 530 | 2005 |
| Isolation and functional characterization of murine prostate stem cells DA Lawson, LI Xin, RU Lukacs, D Cheng, ON Witte Proceedings of the National Academy of Sciences 104 (1), 181-186, 2007 | 472 | 2007 |
| Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation N Choi, B Zhang, L Zhang, M Ittmann, L Xin Cancer cell 21 (2), 253-265, 2012 | 393 | 2012 |
| Basal epithelial stem cells are efficient targets for prostate cancer initiation DA Lawson, Y Zong, S Memarzadeh, L Xin, J Huang, ON Witte Proceedings of the National Academy of Sciences 107 (6), 2610-2615, 2010 | 334 | 2010 |
| ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells Y Zong, L Xin, AS Goldstein, DA Lawson, MA Teitell, ON Witte Proceedings of the National Academy of Sciences 106 (30), 12465-12470, 2009 | 252 | 2009 |
| Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch JB Tennakoon, Y Shi, JJ Han, E Tsouko, MA White, AR Burns, A Zhang, ... Oncogene 33 (45), 5251-5261, 2014 | 234 | 2014 |
| In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme L Xin, H Ide, Y Kim, P Dubey, ON Witte Proceedings of the National Academy of Sciences 100 (suppl_1), 11896-11903, 2003 | 233 | 2003 |
| Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor S Memarzadeh, L Xin, DJ Mulholland, A Mansukhani, H Wu, MA Teitell, ... Cancer cell 12 (6), 572-585, 2007 | 224 | 2007 |
| Lin− Sca-1+ CD49fhigh Stem/Progenitors Are Tumor-Initiating Cells in the Pten-Null Prostate Cancer ModelPten-Null LSC Progenitors Are Tumor-Initiating Cells DJ Mulholland, L Xin, A Morim, D Lawson, O Witte, H Wu Cancer research 69 (22), 8555-8562, 2009 | 220 | 2009 |
| Self‐Renewal and Multilineage Differentiation In Vitro from Murine Prostate Stem Cells L Xin, RU Lukacs, DA Lawson, D Cheng, ON Witte Stem cells 25 (11), 2760-2769, 2007 | 220 | 2007 |
| NKX3. 1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss Q Lei, J Jiao, L Xin, CJ Chang, S Wang, J Gao, ME Gleave, ON Witte, ... Cancer cell 9 (5), 367-378, 2006 | 212 | 2006 |
| Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin OJ Kwon, L Zhang, MM Ittmann, L Xin Proceedings of the National Academy of Sciences 111 (5), E592-E600, 2014 | 205 | 2014 |
| Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor L Xin, MA Teitell, DA Lawson, A Kwon, IK Mellinghoff, ON Witte Proceedings of the National Academy of Sciences 103 (20), 7789-7794, 2006 | 196 | 2006 |
| Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation. ZX Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI ... Nature Cell Biology 18 (6), 632-44, 2016 | 193 | 2016 |
| Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth E Tsouko, AS Khan, MA White, JJ Han, Y Shi, FA Merchant, MA Sharpe, ... Oncogenesis 3 (5), e103-e103, 2014 | 162 | 2014 |
| Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression H Ide, DB Seligson, S Memarzadeh, L Xin, S Horvath, P Dubey, MB Flick, ... Proceedings of the National Academy of Sciences 99 (22), 14404-14409, 2002 | 135 | 2002 |
| ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency L Zhang, JM Valdez, B Zhang, L Wei, J Chang, L Xin PloS one 6 (3), e18271, 2011 | 119 | 2011 |
| SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. MN Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B ... Oncogene, 2017 | 107 | 2017 |
| Cells of origin for cancer: an updated view from prostate cancer L Xin Oncogene 32 (32), 3655-3663, 2013 | 101 | 2013 |
| Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells OJ Kwon, JM Valdez, L Zhang, B Zhang, X Wei, Q Su, MM Ittmann, ... Nature communications 5 (1), 1-15, 2014 | 97 | 2014 |
