| A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ... Cancer cell 36 (6), 660-673. e11, 2019 | 337 | 2019 |
| The RasGAP gene, RASAL2, is a tumor and metastasis suppressor SK McLaughlin, SN Olsen, B Dake, T De Raedt, E Lim, RT Bronson, ... Cancer cell 24 (3), 365-378, 2013 | 146 | 2013 |
| Loss of RasGAP tumor suppressors underlies the aggressive nature of luminal B breast cancers SN Olsen, A Wronski, Z Castaño, B Dake, C Malone, T De Raedt, M Enos, ... Cancer discovery 7 (2), 202-217, 2017 | 65 | 2017 |
| Functional and Structural Characterization of a (+)-Limonene Synthase from Citrus sinensis BR Morehouse, RP Kumar, JO Matos, SN Olsen, S Entova, DD Oprian Biochemistry 56 (12), 1706-1715, 2017 | 62 | 2017 |
| MLL:: AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape SN Olsen, L Godfrey, JP Healy, YA Choi, Y Kai, C Hatton, F Perner, ... Molecular cell 82 (6), 1140-1155. e11, 2022 | 41 | 2022 |
| IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia BJ Aubrey, JA Cutler, W Bourgeois, KA Donovan, S Gu, C Hatton, ... Nature cancer 3 (5), 595-613, 2022 | 33 | 2022 |
| KDM6A epigenetically regulates subtype plasticity in small cell lung cancer L Duplaquet, Y Li, MA Booker, Y Xie, SN Olsen, RA Patel, D Hong, ... Nature Cell Biology 25 (9), 1346-1358, 2023 | 28 | 2023 |
| Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML W Bourgeois, JA Cutler, BJ Aubrey, DV Wenge, F Perner, C Martucci, ... Blood 143 (15), 1513-1527, 2024 | 12 | 2024 |
| It’s not what you say but how you say it: targeting RNA methylation in AML SN Olsen, SA Armstrong Molecular cell 78 (6), 996-998, 2020 | 11 | 2020 |
| A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes AE Smolko, DW Sullivan, SN Olsen, H Kang, SD Whedon, JB Baell, ... Proceedings of the National Academy of Sciences 121 (26), e2405905121, 2024 | 3 | 2024 |
| Menin Inhibitor Induced Menin Protein Degradation Contributes to Menin Inhibitor Efficacy J Cutler, J Tsai, B Regalado, W Bourgeois, D Wenge, J Kim, R Nowak, ... Blood 142, 2788, 2023 | 1 | 2023 |
| Isolation, Purification, and Characterization of (+)-4R-limonene synthase: The first step in exploring enzyme stereospecificity in terpenoid biosynthesis SN Olsen Brandeis University, 2011 | 1 | 2011 |
| Abstract A025: KAT6A/B and Menin-MLL complexes coordinately regulate estrogen receptor-driven gene expression programs in breast cancer SN Olsen, B Anderson, C Hatton, R Jeselsohn, M Brown, E Toska, ... Molecular Cancer Therapeutics 23 (6_Supplement), A025-A025, 2024 | | 2024 |
| Abstract PR012: KAT6A/B and Menin-MLL complexes coordinately regulate estrogen receptor-driven gene expression programs in breast cancer SN Olsen, B Anderson, C Hatton, R Jeselsohn, M Brown, E Toska, ... Molecular Cancer Therapeutics 23 (6_Supplement), PR012-PR012, 2024 | | 2024 |
| Targeted MLL-AF9 degradation is phenocopied by combined DOT1L and Menin inhibition SN Olsen, L Godfrey, JP Healy, C Hatton, SA Armstrong Cancer Research 82 (12_Supplement), 681-681, 2022 | | 2022 |
| Elucidating the Role of RasGAP Genes as Tumor Suppressors in Breast Cancer SN Olsen Harvard University, 2017 | | 2017 |
| Suggested searches AE Smolko, DW Sullivan, SN Olsen, H Kang, SD Whedon, JB Baell, ... | | |
