Allosteric antagonist modulation of TRPV2 by piperlongumine impairs glioblastoma progression J Conde, RA Pumroy, C Baker, T Rodrigues, A Guerreiro, BB Sousa, ... ACS Central Science 7 (5), 868-881, 2021 | 44 | 2021 |
Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, ... Journal of the American Chemical Society 144 (23), 10396-10406, 2022 | 33 | 2022 |
Structural insights into TRPV2 activation by small molecules RA Pumroy, AD Protopopova, TC Fricke, IU Lange, FM Haug, PT Nguyen, ... Nature communications 13 (1), 2334, 2022 | 31 | 2022 |
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors JD Seixas, BB Sousa, MC Marques, A Guerreiro, R Traquete, T Rodrigues, ... RSC Chemical Biology 1 (4), 251-262, 2020 | 12* | 2020 |
TRPV2 interaction with small molecules and lipids revealed by cryo-EM AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, ... BioRxiv, 2020.08. 10.242008, 2020 | 8 | 2020 |
Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo TCL Kohs, SR Olson, J Pang, KR Jordan, TJ Zheng, A Xie, J Hodovan, ... Cellular and Molecular Bioengineering 15 (3), 231-243, 2022 | 7 | 2022 |
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, ... Angewandte Chemie 135 (28), e202304449, 2023 | 6 | 2023 |
Merging the Isonitrile‐Tetrazine (4+ 1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, ... Angewandte Chemie International Edition 62 (44), e202311186, 2023 | 3 | 2023 |
Selective inhibition of Bruton’s tyrosine kinase by a designed covalent ligand leads to potent therapeutic efficacy in blood cancers relative to clinically used inhibitors BB Sousa, CR de Almeida, AF Barahona, R Lopes, A Martins-Logrado, ... ACS Pharmacology & Translational Science 5 (11), 1156-1168, 2022 | 3 | 2022 |
A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening BB Sousa, MFQ Sousa, MC Marques, JD Seixas, JA Brito, PM Matias, ... Bioprocess and biosystems engineering 44, 209-215, 2021 | 1 | 2021 |
Design and Evaluation of PROTACs Targeting Acyl Protein Thioesterase 1 LAR Carvalho, BB Sousa, D Zaidman, H Kiely‐Collins, GJL Bernardes ChemBioChem 25 (4), e202300736, 2024 | | 2024 |
Targeting cancer-related proteins: rational design of covalent inhibitors and degraders for TEC kinases and serine hydrolases BB Sousa | | 2023 |
TRPV2 Modulation by Small Molecules and Lipids AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, ... Biophysical Journal 120 (3), 112a, 2021 | | 2021 |
CRYSTAL STRUCTURE OF BONE MARROW TYROSINE KINASE FROM CHROMOSOME X WITH COVALENT LIGANDS BBDACB SOUSA | | 2018 |